Basic And Clinical Pharmacology 15Th Edition Katzung Trevor Test Bank Inclusive Of Chapters 1-66 Complete With Explained Answers

BASIC AND CLINICAL PHARMACOLOGY 15TH EDITION
KATZUNG TREVOR TEST BANK
INCLUSIVE OF CHAPTERS 1-66 COMPLETE WITH EXPLAINED ANSWERS

, Page 2 of 822 ln ln ln




Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
ln ln ln ln ln ln ln ln l n




Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
ln ln ln ln ln ln ln ln ln ln ln




1.
A nurse working in radiology administers iodine to a patient who is havin
ln ln ln ln ln ln ln ln ln ln ln ln


g a computed tomography (CT) scan. The nurse working on the oncology un
ln ln ln ln ln ln ln ln ln ln ln ln


it administers chemotherapy to patients who have cancer. At the Public Healt
ln ln ln ln ln ln ln ln ln ln ln


h Department, a nurse administers a measles-mumps-
ln ln ln ln ln ln


rubella (MMR) vaccine to a 14-month- ln ln ln ln ln


old child as a routine immunization. Which branch of pharmacology best des
ln ln ln ln ln ln ln ln ln ln ln


cribes the actions of all three nurses?
ln ln ln ln ln l n




A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:

Pharmacology is the study of the biologic effects of chemicals. Nurses are in
ln ln ln ln ln ln ln ln ln ln ln ln


volved with clinical pharmacology or pharmacotherapeutics, which is a bran
ln ln ln ln ln ln ln ln ln


ch of pharmacology that deals with the uses of drugs to treat, prevent, and di
ln ln ln ln ln ln ln ln ln ln ln ln ln ln


agnose disease. The radiology nurse is administering a drug to help diagnose
ln ln ln ln ln ln ln ln ln ln ln


a disease. The oncology nurse is administering a drug to help treat a disease.
ln ln ln ln ln ln ln ln ln ln ln ln ln ln ln


Pharmacoeconomics includes any costs involved in drug therapy. ln ln ln ln ln ln ln


Pharmacodynamics involves how a drug affects the body and pharmacokinetic ln ln ln ln ln ln ln ln ln


s is how the body acts on the body.
ln ln ln ln ln ln ln ln




2.
When involved in phase III drug evaluation studies, wh
ln ln ln ln ln ln ln ln


at responsibilities would the nurse have?
ln ln ln ln ln




A) Working with animals who are given experimental drugs
ln ln ln ln ln ln ln




B) Choosing appropriate patients to be involved in the drug study
ln ln ln ln ln ln ln ln ln




C) Monitoring and observing patients closely for adverse effects
ln ln ln ln ln ln ln




D) Conducting research to determine effectiveness of the drugln ln ln ln ln ln ln

, Page 3 of 822 ln ln ln




Ans: C
Feedback:

Phase III studies involve use of a drug in a vast clinical population in which
ln ln ln ln ln ln ln ln ln ln ln ln ln ln ln


patients are asked to record any symptoms they experience while taking the
ln ln ln ln ln ln ln ln ln ln ln ln


drugs. Nurses may be responsible for helping collect and analyze the inform
ln ln ln ln ln ln ln ln ln ln ln


ation to be shared with the Food and Drug Administration (FDA) but would
ln ln ln ln ln ln ln ln ln ln ln ln ln


not conduct research independently because nurses do not prescribe medicat
ln ln ln ln ln ln ln ln ln


ions. Use of animals in drug testing is done in the preclinical trials. Select p
ln ln ln ln ln ln ln ln ln ln ln ln ln ln


atients who are involved in phase II studies to participate in studies where th
ln ln ln ln ln ln ln ln ln ln ln ln ln


e participants have the disease the drug is intended to treat. These patients ar
ln ln ln ln ln ln ln ln ln ln ln ln ln


e monitored closely for drug action and adverse effects. Phase I studies invo
ln ln ln ln ln ln ln ln ln ln ln ln


lve healthy human volunteers who are usually paid for their participation. N
ln ln ln ln ln ln ln ln ln ln ln


urses may observe for adverse effects and toxicity.
ln ln ln ln ln ln ln




3.
A physician has ordered intramuscular (IM) injections of morphine, a nar
ln ln ln ln ln ln ln ln ln ln


cotic, every 4 hours as needed for pain in a motor vehicle accident victim. Th
ln ln ln ln ln ln ln ln ln ln ln ln ln ln


e nurse is aware this drug has a high abuse potential. Under what category w
ln ln ln ln ln ln ln ln ln ln ln ln ln ln


ould morphine be classified?
ln ln ln




A) Schedule I ln




B) Schedule II ln




C) Schedule III ln




D) Schedule IV ln




Ans: B
Feedback:

Narcotics with a high abuse potential are classified as Schedule II drugs be
ln ln ln ln ln ln ln ln ln ln ln ln


cause of severe dependence liability. Schedule I drugs have high abuse pot
ln ln ln ln ln ln ln ln ln ln ln


ential and no accepted medical use. Schedule III drugs have a lesser abuse
ln ln ln ln ln ln ln ln ln ln ln ln ln


potential than II and an accepted medical use. Schedule IV drugs have low a
ln ln ln ln ln ln ln ln ln ln ln ln ln


buse potential and limited dependence liability.
ln ln ln ln ln




4.
What concept is considered when generic drugs are substituted for bran
ln ln ln ln ln ln ln ln ln ln


d name drugs?
ln ln




A) Bioavailability

, Page 4 of 822 ln ln ln




B) Critical concentration ln




C) Distribution
D) Half-life
Ans: A
Feedback:

Bioavailability is the portion of a dose of a drug that reaches the systemic c ln ln ln ln ln ln ln ln ln ln ln ln ln ln


irculation and is available to act on body cells. Binders used in a generic dr
ln ln ln ln ln ln ln ln ln ln ln ln ln ln


ug may not be the same as those used in the brand name drug. Therefore, t
ln ln ln ln ln ln ln ln ln ln ln ln ln ln ln


he way the body breaks down and uses the drug may differ, which may eli
ln ln ln ln ln ln ln ln ln ln ln ln ln ln


minate a generic drug substitution. Critical concentration is the amount of a d
ln ln ln ln ln ln ln ln ln ln ln ln


rug that is needed to cause a therapeutic effect and should not differ betwee
ln ln ln ln ln ln ln ln ln ln ln ln ln


n generic and brand name medications. Distribution is the phase of pharma
ln ln ln ln ln ln ln ln ln ln ln


cokinetics, which involves the movement of a drug to the bodys tissues and
ln ln ln ln ln ln ln ln ln ln ln ln l


is the same in generic and brand name drugs. A drugs half-
n ln ln ln ln ln ln ln ln ln ln ln


life is the time it takes for the amount of drug to decrease to half the peak l
ln ln ln ln ln ln ln ln ln ln ln ln ln ln ln ln ln


evel, which should not change when substituting a generic medication.
ln ln ln ln ln ln ln ln l n




5.
A nurse is assessing the patients home medication use. After listening to th
ln ln ln ln ln ln ln ln ln ln ln ln


e patient list current medications, the nurse asks what priority question?
ln ln ln ln ln ln ln ln ln ln




A) Do you take any generic medications?
ln ln ln ln ln




B) Are any of these medications orphan drugs?
ln ln ln ln ln ln




C) Are these medications safe to take during pregnancy?
ln ln ln ln ln ln ln




D) Do you take any over-the-counter medications?
ln ln ln ln ln




Ans: D
Feedback:

It is important for the nurse to specifically question use of over-the-
ln ln ln ln ln ln ln ln ln ln ln


counter medications because patients may not consider them important. The
ln ln ln ln ln ln ln ln ln l


npatient is unlikely to know the meaning of orphan drugs unless they too are
ln ln ln ln ln ln ln ln ln ln ln ln ln l


nhealth care providers. Safety during pregnancy, use of a generic medication
ln ln ln ln ln ln ln ln ln ln


, or classification of orphan drugs are things the patient would be unable to
ln ln ln ln ln ln ln ln ln ln ln ln ln ln


answer but could be found in reference books if the nurse wishes to research t
ln ln ln ln ln ln ln ln ln ln ln ln ln ln


hem.