NR607 /NR 607 FINAL Exam 2026-2027 BANK QUESTIONS
WITH DETAILED VERIFIED ANSWERS EXAM QUESTIONS
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1. A 72-year-old male presents with gradual-onset memory loss,
difficulty finding words, and apathy. Neuroimaging reveals bilateral
temporal lobe atrophy. Which of the following is the most likely
diagnosis?
A. Alzheimer's disease
B. Frontotemporal dementia
C. Vascular dementia
D. Dementia with Lewy bodies
Answer: B. Frontotemporal dementia. The combination of early
behavioral changes (apathy), language difficulty, and bilateral temporal
lobe atrophy is classic for frontotemporal dementia. Alzheimer's
typically shows hippocampal and parietal atrophy. Vascular dementia
has a stepwise course. Lewy body dementia features visual
hallucinations and parkinsonism.
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2. Which neurotransmitter is primarily depleted in the nigrostriatal
pathway in Parkinson's disease?
A. Acetylcholine
B. Serotonin
C. Dopamine
D. Norepinephrine
Answer: C. Dopamine. Parkinson's disease is characterized by the loss of
dopaminergic neurons in the substantia nigra pars compacta, leading to
dopamine depletion in the nigrostriatal pathway. This underlies the
motor symptoms of bradykinesia, rigidity, and tremor.
3. A 45-year-old female with systemic lupus erythematosus presents
with acute confusion, headache, and seizure. Which of the following is
the most appropriate initial diagnostic test?
A. CT head without contrast
B. Lumbar puncture
C. MRI brain with contrast
D. EEG
Answer: C. MRI brain with contrast. In CNS lupus, MRI is the most
sensitive imaging modality to detect white matter lesions, atrophy, or
infarcts. CT may be normal early. Lumbar puncture and EEG are
adjunctive but not the initial test of choice.
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4. Which of the following medications is contraindicated in acute angle-
closure glaucoma?
A. Pilocarpine
B. Timolol
C. Atropine
D. Latanoprost
Answer: C. Atropine. Atropine is a muscarinic antagonist that causes
mydriasis and can precipitate acute angle-closure glaucoma in
susceptible patients. Pilocarpine, timolol, and latanoprost are used to
lower intraocular pressure.
5. A patient with chronic kidney disease develops sudden-onset, severe,
tearing chest pain radiating to the back. Blood pressure is 180/110
mmHg in the right arm and 140/90 mmHg in the left arm. What is the
most likely diagnosis?
A. Myocardial infarction
B. Pulmonary embolism
C. Aortic dissection
D. Pericarditis
Answer: C. Aortic dissection. The classic presentation of aortic dissection
includes severe tearing chest pain, radiation to the back, and
differential blood pressures between arms. This is a medical emergency
requiring immediate imaging and surgical consultation.
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6. Which of the following is the most common organism causing
community-acquired pneumonia in adults?
A. Mycoplasma pneumoniae
B. Streptococcus pneumoniae
C. Haemophilus influenzae
D. Legionella pneumophila
Answer: B. Streptococcus pneumoniae. S. pneumoniae remains the most
common cause of community-acquired pneumonia in adults. Atypical
organisms like Mycoplasma are more common in younger patients and
outbreaks.
7. A 60-year-old smoker presents with hemoptysis, weight loss, and
hoarseness. Chest CT shows a hilar mass with mediastinal
lymphadenopathy. Which of the following is the most likely diagnosis?
A. Small cell lung cancer
B. Squamous cell carcinoma
C. Adenocarcinoma
D. Mesothelioma
Answer: B. Squamous cell carcinoma. Squamous cell carcinoma is
strongly associated with smoking and often presents as a central hilar
mass with cavitation, hemoptysis, and hoarseness due to recurrent