COMSAE Phase 1 Form 105: High-Yield
Practice Exam –Questions with Answers &
Rationales
,Question 1
A 65-year-old man presents with chest pain radiating to his left arm. ECG shows ST-segment
elevation in leads II, III, and aVF. Which coronary artery is most likely occluded?
A) Left anterior descending artery
B) Right coronary artery
C) Left circumflex artery
D) Posterior descending artery
Answer: B) Right coronary artery
Rationale: Inferior wall myocardial infarction is indicated by ST elevation in leads II, III, and aVF.
The right coronary artery most commonly supplies the inferior wall of the heart in right-dominant
circulation.
,Question 2
A patient presents with fatigue, pallor, and a mean corpuscular volume (MCV) of 72 fL. Which
condition is most likely?
A) Vitamin B12 deficiency
B) Iron deficiency anemia
C) Aplastic anemia
D) Folate deficiency
Answer: B) Iron deficiency anemia
Rationale: Microcytic anemia (MCV < 80 fL) is most commonly caused by iron deficiency, often
due to chronic blood loss or inadequate intake. Low ferritin and high TIBC confirm the diagnosis.
Question 3
, Which organism is most commonly associated with peptic ulcer disease?
A) Helicobacter pylori
B) Escherichia coli
C) Staphylococcus aureus
D) Clostridium difficile
Answer: A) Helicobacter pylori
Rationale: H. pylori is a spiral-shaped bacterium that colonizes the gastric mucosa, causing
chronic gastritis and peptic ulcer disease. It increases the risk of gastric cancer.
Question 4
Which vitamin deficiency is associated with Wernicke's encephalopathy?
Practice Exam –Questions with Answers &
Rationales
,Question 1
A 65-year-old man presents with chest pain radiating to his left arm. ECG shows ST-segment
elevation in leads II, III, and aVF. Which coronary artery is most likely occluded?
A) Left anterior descending artery
B) Right coronary artery
C) Left circumflex artery
D) Posterior descending artery
Answer: B) Right coronary artery
Rationale: Inferior wall myocardial infarction is indicated by ST elevation in leads II, III, and aVF.
The right coronary artery most commonly supplies the inferior wall of the heart in right-dominant
circulation.
,Question 2
A patient presents with fatigue, pallor, and a mean corpuscular volume (MCV) of 72 fL. Which
condition is most likely?
A) Vitamin B12 deficiency
B) Iron deficiency anemia
C) Aplastic anemia
D) Folate deficiency
Answer: B) Iron deficiency anemia
Rationale: Microcytic anemia (MCV < 80 fL) is most commonly caused by iron deficiency, often
due to chronic blood loss or inadequate intake. Low ferritin and high TIBC confirm the diagnosis.
Question 3
, Which organism is most commonly associated with peptic ulcer disease?
A) Helicobacter pylori
B) Escherichia coli
C) Staphylococcus aureus
D) Clostridium difficile
Answer: A) Helicobacter pylori
Rationale: H. pylori is a spiral-shaped bacterium that colonizes the gastric mucosa, causing
chronic gastritis and peptic ulcer disease. It increases the risk of gastric cancer.
Question 4
Which vitamin deficiency is associated with Wernicke's encephalopathy?
