CHAMBERLAIN UNIVERSITY
COMPREHENSIVE EXAM ASSESSMENT
(CEA) 600 EXPERT QUESTIONS AND
VERIFIED ANSWERS WITH RATIONALES
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1. A 73-year-old male reports sleeping from 9:30 PM to 4:45 AM, wishing he could sleep later as he did in youth,
but denies daytime sleepiness. What is the best response?
A) Add Insomnia Disorder diagnosis and begin non-pharmacological sleep measures
B) Add Insomnia Disorder and prescribe Trazodone 25mg at bedtime
C) Educate that total sleep time is adequate and this is an age-dependent shift
D) All of these should be done
Answer: C This sleep pattern is consistent with advanced sleep phase syndrome, a common age-related
change that does not meet Insomnia Disorder criteria as there is no distress or daytime impairment;
education is most appropriate.
2. Which finding most strongly supports a diagnosis of stable angina in a 64-year-old with hypertension and
exertional chest pain?
A) ST elevation on ECG
B) Chest pain lasting longer than 30 minutes
C) Pain precipitated by exertion and relieved by nitroglycerin
D) Elevated troponin levels
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,Answer: C Stable angina is characterized by predictable chest pain triggered by exertion or stress and
relieved by rest or nitroglycerin; ST elevation and elevated troponins suggest myocardial infarction.
3. A patient with schizophrenia has taken antipsychotic medication faithfully but shows worsening positive
symptoms. What is the least likely clinical consideration?
A) Novel gene variant altering drug metabolism
B) Active alcohol or substance use
C) Development of tolerance to therapeutic effect
D) Exacerbation due to psychosocial stress
Answer: C Tolerance to antipsychotic therapeutic effects is rare; more common considerations include
substance use, non-adherence, genetic variability in metabolism, and psychosocial stressors exacerbating
illness.
4. Which is considered a protective factor for suicide in a patient with schizophrenia?
A) Frequent hospitalizations
B) Presence of medication side effects
C) Previous suicide attempt
D) Sense of purpose
Answer: D A sense of purpose serves as a protective factor against suicide; previous attempts and
hospitalization are risk factors, and medication side effects may increase distress.
5. A patient with COPD demonstrates pursed-lip breathing and prolonged expiration. These findings primarily
indicate:
A) Increased airway resistance
B) Reduced lung compliance
C) Impaired gas diffusion
D) Decreased tidal volume
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,Answer: A Pursed-lip breathing helps prevent airway collapse and reduces air trapping caused by increased
airway resistance in COPD.
6. Epigastric pain that improves with meals is most consistent with:
A) Gastric ulcer
B) Duodenal ulcer
C) Acute pancreatitis
D) Cholelithiasis
Answer: B Duodenal ulcer pain typically improves with food intake, whereas gastric ulcer pain worsens after
eating.
7. Which hormone is primarily responsible for lowering blood glucose?
A) Glucagon
B) Cortisol
C) Insulin
D) Epinephrine
Answer: C Insulin promotes glucose uptake into cells and decreases blood glucose levels through multiple
mechanisms including glycogen synthesis and inhibition of gluconeogenesis.
8. Unilateral facial droop with inability to close one eye is most consistent with:
A) Stroke
B) Trigeminal neuralgia
C) Bell's palsy
D) Myasthenia gravis
Answer: C Bell's palsy involves acute unilateral facial nerve paralysis affecting the entire side of the face;
stroke typically spares the forehead due to bilateral innervation.
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, 9. Which neurocognitive disorder has insidious onset, recurrent hallucinations, pronounced variation in attention,
and dramatic sensitivity to antipsychotics?
A) Huntington's disease
B) Lewy body disease
C) Alzheimer's disease
D) Frontotemporal lobar degeneration
Answer: B Core features of Lewy body disease include fluctuating cognition, well-formed recurrent visual
hallucinations, and parkinsonism; severe antipsychotic sensitivity is a characteristic feature.
10. A 37-year-old collects comic books excessively, cannot part with them, and continues purchasing despite space
constraints. What is the best diagnosis?
A) Nonpathological behavior
B) Hoarding disorder, excessive acquisition type
C) Obsessive compulsive disorder
D) Delusional disorder
Answer: B Hoarding disorder involves persistent difficulty discarding possessions regardless of value, with
excessive acquisition and significant clutter causing functional impairment.
11. A child who "annoys others," demonstrates defiance, blames others, and argues with adults most likely has:
A) Major depressive disorder
B) Conduct disorder
C) Oppositional defiant disorder
D) Intermittent explosive disorder
Answer: C Oppositional defiant disorder is characterized by a pattern of angry/irritable mood,
argumentative/defiant behavior, and vindictiveness lasting at least six months.
12. Which symptom is most consistent with hypothyroidism?
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