Week 3 UTA ADV Pharm 5334 Skin drugs QUIZ 2 Exam
#1 Questions with correct answers
What are the three layers of the skin? - ✔✔Hypodermis, Dermis, Epidermis
What is the primary function of the epidermis? - ✔✔It serves as the outermost
layer containing lipids and keratin.
What are the main functions of the skin? - ✔✔Protection, temperature
regulation, defense against infections and toxins, and conversion of vitamin D
from sunlight.
What tools are commonly used in skin examinations? - ✔✔Handheld lights and
dermatoscopes, with Woods lamp (UV light) for illuminating fungal infections.
What is the significance of SPF in sunscreen? - ✔✔SPF indicates the length of time
one can be exposed to sunlight before burning, calculated as MED on protected
skin divided by MED on unprotected skin.
What is the difference between sunscreen and sunblock? - ✔✔Sunscreen
prevents burning rays, while sunblock prevents all radiation rays.
What are the types of UV radiation and their effects? - ✔✔UVA and UVB; UVA is
considered the lesser of two evils.
What is the minimum erythema dose (MED)? - ✔✔The minimum amount of UV
exposure that results in erythema.
,What are glucocorticoids used for in dermatology? - ✔✔They are used to reduce
inflammation and are potent based on their vasoconstrictive properties.
What are the adverse effects of glucocorticoids? - ✔✔Skin atrophy, purpura,
acneiform eruptions, local infections, and growth retardation in children.
What defines acne vulgaris? - ✔✔Overproduction of sebum, overgrowth of
bacteria, and inflammation.
What are the classifications of acne? - ✔✔Mild (comedones), Moderate (pustules,
papules, small nodules), Severe (large nodules, cysts, pustular areas).
What are retinoids and their function? - ✔✔Vitamin D derivatives that influence
cell proliferation, immune function, inflammation, and sebum production.
What is the prototype drug in the retinoid family? - ✔✔Tretinoin.
What is benzoyl peroxide used for? - ✔✔First-line treatment for mild to moderate
acne without inflammation; it acts as an antiseptic.
What is salicylic acid's function? - ✔✔A beta hydroxy acid that exfoliates, clears
comedones, and has mild anti-inflammatory properties.
What is azelaic acid used for? - ✔✔It is antibacterial against P. acnes and
normalizes keratin production, used for mild to moderate inflammatory acne.
, What are the types of antibiotics used for acne? - ✔✔Topical (e.g., clindamycin,
erythromycin) and oral (e.g., doxycycline, minocycline).
What is the role of combination therapy in acne treatment? - ✔✔It varies by
severity: Mild (topical retinoid), Moderate (topical retinoid + oral antibiotic),
Severe (oral antibiotic + topical retinoid + BPO).
What special considerations are there for isotretinoin (Accutane)? - ✔✔It is the
only agent that prevents scarring, requires special certification, and has significant
adverse effects.
What are the adverse effects of isotretinoin? - ✔✔Photosensitivity, skin irritation,
and potential for severe birth defects.
What should patients using isotretinoin be advised regarding sun exposure? -
✔✔They must use SPF 40+ sunscreen due to increased photosensitivity.
What is the importance of drug holidays in glucocorticoid therapy? - ✔✔To
prevent tachyphylaxis, ensuring continued effectiveness of the treatment.
What are the signs of photoaging? - ✔✔Dark spots, wrinkles, yellowish tint to
skin, fragile blood vessels, leathery skin, and increased risk of skin cancers.
What is the significance of vehicle choice in dermatological treatments? -
✔✔Different vehicles (lotion, cream, ointment, gel, solution, foam) affect
therapeutic efficacy.
#1 Questions with correct answers
What are the three layers of the skin? - ✔✔Hypodermis, Dermis, Epidermis
What is the primary function of the epidermis? - ✔✔It serves as the outermost
layer containing lipids and keratin.
What are the main functions of the skin? - ✔✔Protection, temperature
regulation, defense against infections and toxins, and conversion of vitamin D
from sunlight.
What tools are commonly used in skin examinations? - ✔✔Handheld lights and
dermatoscopes, with Woods lamp (UV light) for illuminating fungal infections.
What is the significance of SPF in sunscreen? - ✔✔SPF indicates the length of time
one can be exposed to sunlight before burning, calculated as MED on protected
skin divided by MED on unprotected skin.
What is the difference between sunscreen and sunblock? - ✔✔Sunscreen
prevents burning rays, while sunblock prevents all radiation rays.
What are the types of UV radiation and their effects? - ✔✔UVA and UVB; UVA is
considered the lesser of two evils.
What is the minimum erythema dose (MED)? - ✔✔The minimum amount of UV
exposure that results in erythema.
,What are glucocorticoids used for in dermatology? - ✔✔They are used to reduce
inflammation and are potent based on their vasoconstrictive properties.
What are the adverse effects of glucocorticoids? - ✔✔Skin atrophy, purpura,
acneiform eruptions, local infections, and growth retardation in children.
What defines acne vulgaris? - ✔✔Overproduction of sebum, overgrowth of
bacteria, and inflammation.
What are the classifications of acne? - ✔✔Mild (comedones), Moderate (pustules,
papules, small nodules), Severe (large nodules, cysts, pustular areas).
What are retinoids and their function? - ✔✔Vitamin D derivatives that influence
cell proliferation, immune function, inflammation, and sebum production.
What is the prototype drug in the retinoid family? - ✔✔Tretinoin.
What is benzoyl peroxide used for? - ✔✔First-line treatment for mild to moderate
acne without inflammation; it acts as an antiseptic.
What is salicylic acid's function? - ✔✔A beta hydroxy acid that exfoliates, clears
comedones, and has mild anti-inflammatory properties.
What is azelaic acid used for? - ✔✔It is antibacterial against P. acnes and
normalizes keratin production, used for mild to moderate inflammatory acne.
, What are the types of antibiotics used for acne? - ✔✔Topical (e.g., clindamycin,
erythromycin) and oral (e.g., doxycycline, minocycline).
What is the role of combination therapy in acne treatment? - ✔✔It varies by
severity: Mild (topical retinoid), Moderate (topical retinoid + oral antibiotic),
Severe (oral antibiotic + topical retinoid + BPO).
What special considerations are there for isotretinoin (Accutane)? - ✔✔It is the
only agent that prevents scarring, requires special certification, and has significant
adverse effects.
What are the adverse effects of isotretinoin? - ✔✔Photosensitivity, skin irritation,
and potential for severe birth defects.
What should patients using isotretinoin be advised regarding sun exposure? -
✔✔They must use SPF 40+ sunscreen due to increased photosensitivity.
What is the importance of drug holidays in glucocorticoid therapy? - ✔✔To
prevent tachyphylaxis, ensuring continued effectiveness of the treatment.
What are the signs of photoaging? - ✔✔Dark spots, wrinkles, yellowish tint to
skin, fragile blood vessels, leathery skin, and increased risk of skin cancers.
What is the significance of vehicle choice in dermatological treatments? -
✔✔Different vehicles (lotion, cream, ointment, gel, solution, foam) affect
therapeutic efficacy.
