OCN Exam Questions and Answers with
Verified Solutions | Latest Updated 2026
What population is AML higher in? Males and in European Descent
What is a subtype of AML? APL
APL is more prevalent in.... Latino and Hispanics
What are the six groups of 1. Nitrogen Mustards
alkylating 2. Etyhlenamine and methylenaimie
agents? deriatives.
3. Alkyl Sulfonates
4. Nitrosureas
5. Triazenes
6. Platinum Drugs
What are some drugs that are Cytoxan, Ifos
considered nitrogen mustards?
How do alkylating agents work? Act by inhibiting the transcription of DNA
into RNA
and stops protein synthesis.
Alkylating agents work on... They work on all cells but work best on
cells that
are rapidly dividing such as cancer cells.
, Alkylating agents also work on Hematopoetic, reproductive and
what endothelial cells
other rapidly dividing cells... which accounts for SE such as anemia,
pancytopenia, amenorrhea, impaired
spermatogenesis, mucosal damage,
alopecia and
increased risk of malignancy.
What are the major toxicities in the BM and GI Tract
alkylating agents?
What causes sinusoidal Alkylating Agents
obstruction
syndrome?
What type of patients are at a WBC > 100,000
higher
risk for TLS when presenting with
AML?
What is leukostasis? WBC > 100,000
What are 2 oncologic Leukostasis and TLS
emergencies?
What is a common presentation DIC with bleeding diathesis
with
APL?
Verified Solutions | Latest Updated 2026
What population is AML higher in? Males and in European Descent
What is a subtype of AML? APL
APL is more prevalent in.... Latino and Hispanics
What are the six groups of 1. Nitrogen Mustards
alkylating 2. Etyhlenamine and methylenaimie
agents? deriatives.
3. Alkyl Sulfonates
4. Nitrosureas
5. Triazenes
6. Platinum Drugs
What are some drugs that are Cytoxan, Ifos
considered nitrogen mustards?
How do alkylating agents work? Act by inhibiting the transcription of DNA
into RNA
and stops protein synthesis.
Alkylating agents work on... They work on all cells but work best on
cells that
are rapidly dividing such as cancer cells.
, Alkylating agents also work on Hematopoetic, reproductive and
what endothelial cells
other rapidly dividing cells... which accounts for SE such as anemia,
pancytopenia, amenorrhea, impaired
spermatogenesis, mucosal damage,
alopecia and
increased risk of malignancy.
What are the major toxicities in the BM and GI Tract
alkylating agents?
What causes sinusoidal Alkylating Agents
obstruction
syndrome?
What type of patients are at a WBC > 100,000
higher
risk for TLS when presenting with
AML?
What is leukostasis? WBC > 100,000
What are 2 oncologic Leukostasis and TLS
emergencies?
What is a common presentation DIC with bleeding diathesis
with
APL?
