Clinical Immunology Final Exam
Questions with Correct Answers
Sjogren's Syndrome - ANSWERSanti-SSA( Ro) and anti-SSB (La)
Anti-beta-2-glycoprotein-1 in antiphospholipid antibody syndrome - ANSWERSincludes
vasucular thrombosis and recurrent pregnancy loss
TSH mimicking antibody - ANSWERSGraves Disease (hyperthyrodism)
Deamidated gliadin (IgG and IgA) and TTG IgA - ANSWERSCeliac Disease, confirm
negatives by ruling out IgA deficiency
Anti-thyroglobulin and Anti-thyroid peroxidase (microsomal) - ANSWERSHashimoto's
thyroiditis
Anti-SCL70 - ANSWERSprogressive systemic sclerosis (scleroderma)
Anti-Jo1 - ANSWERSpolymyositis
Anti-c-ANCA in Wegener's granulmatosis - ANSWERS(distinguish c-ANCA's
distrubuation throughtout the neutrophil cytoplasm from p-ANCA's perinuclear
distrubition, P-ANCA does not carrry unique specificity for Wegners
Anti-CCP (cyclic citrullinated peptide) - ANSWERSRheumatoid Arthritis
Anti-acetylcholine antibodies - ANSWERSmyasthenia gravis
Why is T-cell function difficult to assess in the lab? - ANSWERST-cell require MHC
restricked antigen presentation,
Why is B-cell function easier to assess in the lab compared to T-cell? - ANSWERSB-
cells function just measueres antibodies
Automated Anazlyzers sold using chemilumiensecnes - ANSWERSthis is more
sensitive than using florescences
Hetergeneous Assays - ANSWERSrequire seperation of bound from unbound
antibodies
Homogenous Assays - ANSWERSdon't require seperation of antibodies
Questions with Correct Answers
Sjogren's Syndrome - ANSWERSanti-SSA( Ro) and anti-SSB (La)
Anti-beta-2-glycoprotein-1 in antiphospholipid antibody syndrome - ANSWERSincludes
vasucular thrombosis and recurrent pregnancy loss
TSH mimicking antibody - ANSWERSGraves Disease (hyperthyrodism)
Deamidated gliadin (IgG and IgA) and TTG IgA - ANSWERSCeliac Disease, confirm
negatives by ruling out IgA deficiency
Anti-thyroglobulin and Anti-thyroid peroxidase (microsomal) - ANSWERSHashimoto's
thyroiditis
Anti-SCL70 - ANSWERSprogressive systemic sclerosis (scleroderma)
Anti-Jo1 - ANSWERSpolymyositis
Anti-c-ANCA in Wegener's granulmatosis - ANSWERS(distinguish c-ANCA's
distrubuation throughtout the neutrophil cytoplasm from p-ANCA's perinuclear
distrubition, P-ANCA does not carrry unique specificity for Wegners
Anti-CCP (cyclic citrullinated peptide) - ANSWERSRheumatoid Arthritis
Anti-acetylcholine antibodies - ANSWERSmyasthenia gravis
Why is T-cell function difficult to assess in the lab? - ANSWERST-cell require MHC
restricked antigen presentation,
Why is B-cell function easier to assess in the lab compared to T-cell? - ANSWERSB-
cells function just measueres antibodies
Automated Anazlyzers sold using chemilumiensecnes - ANSWERSthis is more
sensitive than using florescences
Hetergeneous Assays - ANSWERSrequire seperation of bound from unbound
antibodies
Homogenous Assays - ANSWERSdon't require seperation of antibodies
