ORAL
PATHOLOGY
, DISEASES OF I
BONE JOINTS .
↓
Pagets Disease .
Abnormal
· caused by remodeling of the bons
· over namestillis Deformans
seen in > 50yus
·
age
· Male to Female 1 : .
1
· Most commonly seen un Manilla
maxilla : madible = 2 3 : 1.
Bone most commonly involed lumbar spine and sacrum.
·
,
the skull
·
Platybasia -
softening of the bases of
·
Osteoporosis Circumscripta-
I
single isolated Radiolucent lesion
in the skull
.
12
Cotton wool appearance "
!
R1q-
Histologically -1 It
. has a mosaic pattern
.
.
2 Jigsaw puzzle
.
3 Reversal lines .
Laboratory - Level of Serum Ca ,
Pis
normal
·
Abnormally high alphactX and B ↑
CTX ratio
·
Elevated alkaline phosphatase ↑
·
Increase Urinary Hydron-proline
Clinical Feature - Pain due to increase
vascularity , bone is
warm to touch
PATHOLOGY
, DISEASES OF I
BONE JOINTS .
↓
Pagets Disease .
Abnormal
· caused by remodeling of the bons
· over namestillis Deformans
seen in > 50yus
·
age
· Male to Female 1 : .
1
· Most commonly seen un Manilla
maxilla : madible = 2 3 : 1.
Bone most commonly involed lumbar spine and sacrum.
·
,
the skull
·
Platybasia -
softening of the bases of
·
Osteoporosis Circumscripta-
I
single isolated Radiolucent lesion
in the skull
.
12
Cotton wool appearance "
!
R1q-
Histologically -1 It
. has a mosaic pattern
.
.
2 Jigsaw puzzle
.
3 Reversal lines .
Laboratory - Level of Serum Ca ,
Pis
normal
·
Abnormally high alphactX and B ↑
CTX ratio
·
Elevated alkaline phosphatase ↑
·
Increase Urinary Hydron-proline
Clinical Feature - Pain due to increase
vascularity , bone is
warm to touch