NR 546 Week 2 Assignment; Neurotransmitter Table
NR 546 Week 3 Assignment; Antipsychotic Medications Table
NR 546 Week 8 Assignment; Neurotransmitter Table
Merged Together
, NR 546 Week 2 Assignment; Neurotransmitter Table
Neurotransmitter Table
*
Neuro Receptor Location/Function/Effects Distribution Drug classes that Specific medications that target this
transmitter Subtype /symptoms of excess or (ie: CNS/PNS, target this neurotransmitter or receptor
deficit if applicable GI, vascular) neurotransmitter or
receptor
Glutamate AMPA α-Amino-3-hydroxy-5- CNS AMPA Receptor Perampanel
methyl-4- Antagonists
isoxazolepropionic acid
(AMPA)-type glutamate
receptors (AMPARs)
mediate the majority of
fast excitatory synaptic
transmission in the brain.
AMPA receptors are
abundant and widely
distributed in the central
nervous system.
Hippocampus, outer layer
of the cortex, basal
ganglia, olfactory regions,
lateral septum, and
amygdala of the CNS are
all enriched with GluA1,
GluA2, and GluA3
subunits.
, MNDA N-methyl-D-aspartate CNS NDMA Glutamate NDMA Glutamate Antagonist-
(NMDA) receptors NMDA receptors Antagonist Memantine
represent one of the are found in Phencyclidine
ligand-gated non-selective both synaptic Ketamine
ionotropic glutamate and Dextromethorphan
receptors (iGluRs), which extrasynaptic Dextromethadone
NR 546 Week 3 Assignment; Antipsychotic Medications Table
NR 546 Week 8 Assignment; Neurotransmitter Table
Merged Together
, NR 546 Week 2 Assignment; Neurotransmitter Table
Neurotransmitter Table
*
Neuro Receptor Location/Function/Effects Distribution Drug classes that Specific medications that target this
transmitter Subtype /symptoms of excess or (ie: CNS/PNS, target this neurotransmitter or receptor
deficit if applicable GI, vascular) neurotransmitter or
receptor
Glutamate AMPA α-Amino-3-hydroxy-5- CNS AMPA Receptor Perampanel
methyl-4- Antagonists
isoxazolepropionic acid
(AMPA)-type glutamate
receptors (AMPARs)
mediate the majority of
fast excitatory synaptic
transmission in the brain.
AMPA receptors are
abundant and widely
distributed in the central
nervous system.
Hippocampus, outer layer
of the cortex, basal
ganglia, olfactory regions,
lateral septum, and
amygdala of the CNS are
all enriched with GluA1,
GluA2, and GluA3
subunits.
, MNDA N-methyl-D-aspartate CNS NDMA Glutamate NDMA Glutamate Antagonist-
(NMDA) receptors NMDA receptors Antagonist Memantine
represent one of the are found in Phencyclidine
ligand-gated non-selective both synaptic Ketamine
ionotropic glutamate and Dextromethorphan
receptors (iGluRs), which extrasynaptic Dextromethadone
