CMN 548 TEST 4 ACTUAL TEST PAPER
COMPLETE ANSWER GUIDE 100 PERCENT
VERIFIED REVIEW MATERIAL
⩥ Agonist (full agonist).
Answer: A drug that binds to a specific receptor producing an effect
identical to that usually produced by the neurotransmitter affecting that
receptor
⩥ Pharmacodynamics.
Answer: The time course and intensity of a drug's effect/what the drug
does to the body
⩥ Pharmacokinetics.
Answer: What the body does to a drug
⩥ Tolerance.
Answer: Develops over time a need to use increased doses of a
medication/drug to maintain a clinical effect. Or, a decreased sensitivity
to adverse effects of a drug
⩥ Stevens-Johnson Syndrome.
,Answer: A systemic, immune-mediated reaction that can be fatal or
result in permanent scarring or blindness
⩥ Antagonist.
Answer: A compound that blinds to a receptor that blocks or reduces the
action of another substance at the receptor site
⩥ Hyponatremia.
Answer: Common symptoms of this medication side effect include
confusion, agitation, and lethargy. (tx with oxcarbazepine & SSRIs)
⩥ Therapeutic index.
Answer: ratio of the median toxic dose to the median effective dose
⩥ Somnolence.
Answer: Daytime sleepiness
⩥ Black Box Warning.
Answer: This warning reflects that a medication may cause a serious or
even life-threatening side effect
⩥ Partial or Mixed Agonist.
,Answer: A compound that elicits a partial pharmacological response at
the receptor site involved
⩥ Remission.
Answer: The degree of improvement to below the syndromal threshold
of a disorder
⩥ Paradoxical.
Answer: A response to a drug that represents the clinical effect opposite
of what is expected
⩥ Inverse agonist.
Answer: An agent that binds to the same receptor site as an agonist but
produces the opposite pharmacological effect
⩥ 4 major transmitters.
Answer: Dopamine, Serotonin, GABA, Norepinephrine
⩥ Dopamine transmitter affects?.
Answer: affects mood, Psychosis, ADHD, Addiction
⩥ Serotonin transmitter affects?.
, Answer: Depression, aggression, OCD, Panic, GAD, Social Anxiety,
PTSD, Violence, Sexual dysfunction, substance addiction
⩥ Norepinephrine affects?.
Answer: Affects mood, anxiety, psychosis, ADHD (part), drug
withdrawal
⩥ GABA affects?.
Answer: Fear, anxiety, worry
⩥ Irreversible MAOIs Types.
Answer: MAOa and MAOb
⩥ Irreversible MAOIs medications.
Answer: Phenelzine (Nardil)
isocarboxazid (Marplan)
tranylcypromine (Parnate)
⩥ A single dose of MAOIs may persist in its inhibition of MAO for how
long?.
Answer: because they irreversibly inactivate MAOs, the therapeutic
effect of a single dose of irreversible MAOIs may persist for as long as 2
weeks
COMPLETE ANSWER GUIDE 100 PERCENT
VERIFIED REVIEW MATERIAL
⩥ Agonist (full agonist).
Answer: A drug that binds to a specific receptor producing an effect
identical to that usually produced by the neurotransmitter affecting that
receptor
⩥ Pharmacodynamics.
Answer: The time course and intensity of a drug's effect/what the drug
does to the body
⩥ Pharmacokinetics.
Answer: What the body does to a drug
⩥ Tolerance.
Answer: Develops over time a need to use increased doses of a
medication/drug to maintain a clinical effect. Or, a decreased sensitivity
to adverse effects of a drug
⩥ Stevens-Johnson Syndrome.
,Answer: A systemic, immune-mediated reaction that can be fatal or
result in permanent scarring or blindness
⩥ Antagonist.
Answer: A compound that blinds to a receptor that blocks or reduces the
action of another substance at the receptor site
⩥ Hyponatremia.
Answer: Common symptoms of this medication side effect include
confusion, agitation, and lethargy. (tx with oxcarbazepine & SSRIs)
⩥ Therapeutic index.
Answer: ratio of the median toxic dose to the median effective dose
⩥ Somnolence.
Answer: Daytime sleepiness
⩥ Black Box Warning.
Answer: This warning reflects that a medication may cause a serious or
even life-threatening side effect
⩥ Partial or Mixed Agonist.
,Answer: A compound that elicits a partial pharmacological response at
the receptor site involved
⩥ Remission.
Answer: The degree of improvement to below the syndromal threshold
of a disorder
⩥ Paradoxical.
Answer: A response to a drug that represents the clinical effect opposite
of what is expected
⩥ Inverse agonist.
Answer: An agent that binds to the same receptor site as an agonist but
produces the opposite pharmacological effect
⩥ 4 major transmitters.
Answer: Dopamine, Serotonin, GABA, Norepinephrine
⩥ Dopamine transmitter affects?.
Answer: affects mood, Psychosis, ADHD, Addiction
⩥ Serotonin transmitter affects?.
, Answer: Depression, aggression, OCD, Panic, GAD, Social Anxiety,
PTSD, Violence, Sexual dysfunction, substance addiction
⩥ Norepinephrine affects?.
Answer: Affects mood, anxiety, psychosis, ADHD (part), drug
withdrawal
⩥ GABA affects?.
Answer: Fear, anxiety, worry
⩥ Irreversible MAOIs Types.
Answer: MAOa and MAOb
⩥ Irreversible MAOIs medications.
Answer: Phenelzine (Nardil)
isocarboxazid (Marplan)
tranylcypromine (Parnate)
⩥ A single dose of MAOIs may persist in its inhibition of MAO for how
long?.
Answer: because they irreversibly inactivate MAOs, the therapeutic
effect of a single dose of irreversible MAOIs may persist for as long as 2
weeks
