PAT 201 PRACTICE CERTIFICATION
SCRIPT 2026 QUESTIONS WITH
SOLUTIONS GRADED A+
◍ What are body fluids divided into?.
Answer: Fluid compartments
◍ What does effective use of drugs by a health care team depend on?.
Answer: Being able to apply knowledge related to:- Anatomy & Physiology-
Pathophysiology- Chemistry- Microbiology- CJ- Nursing Process
◍ How many Fluid Compartments are there? What are they?.
Answer: 2 Fluid compartments:1. Intracellular (ICF)2. Extracellular (ECF)
◍ ICF Total Body Fluid.
Answer: 2/3 total body fluid INSIDE the cells
◍ ECF Total Body Fluid.
Answer: 1/3 total body fluid inside the OUTSIDE the cells
◍ Canadian Drug Regulations.
Answer: Created to protect public from drug misuse and provide mechanism
for quality assurance for safety & efficacy
◍ What is ECF composed of?.
Answer: Composed of plasma and ICF:- interstitial fluid- intravascular
fluid- cerebrospinal fluid (CSF)- lymphatic, synovial, intestinal, biliary,
hepatic, pancreatic, pleural, peritoneal, pericardial, and intraocular fluids-
sweat- urine
◍ Distribution of Body Fluids?.
Answer: Fluid moves continuously between ICF and ECF compartments
through semi-permeable cell membranes
,◍ Intracellular Fluid Compartment.
Answer: - Cells: 25 L- 40% of body weight
◍ Health Products and Food Branches (HPFB).
Answer: HPFB of Health Canada is responsible for ensuring safety and
quality of drugs, biologics, and natural health products
◍ Extracellular Fluid Compartment.
Answer: - Interstitial Fluid: 12 L- Plasma: 3 L- 20% of body weight
◍ What separates the Cells and the Interstitial fluid (ICF and ECF).
Answer: Plasma Membrane
◍ What separates Interstitial fluid and Plasma (ECF and ECF).
Answer: Capillary Membrane
◍ Total Body Water: Newborn.
Answer: 70-80% of body weight
◍ Total Body Water: Childhood.
Answer: 60-65% of body weight
◍ What is the standard set by?.
Answer: Food and Drug Act and Regulations
◍ Total Body Water: Adults.
Answer: 50-60% of body weight
◍ Total Body Water: Older Adults.
Answer: Percent declines with age
◍ Who has greater percentage of body water: Men or Women?.
Answer: Men have greater percentage of body water compared with women
◍ Who is at a higher risk for dehydration? Why?.
Answer: Newborns - do not concentrate urine as effectively and have a high
rate of metabolism; high rate of evaporation; large body surface area
compared to their body volume; low residual volume in lungs; not mature
yetSigns to watch for: sleepiness, sunken eyes, skin turgor, less wet diapers
, ◍ How many steps are there for approval of drugs marketed in Canada?.
Answer: 8 steps
◍ Water Movement Between ICF and ECF.
Answer: - Osmolality- Osmotic forces- Sodium for ECF- Potassium for ICF-
Aquaporins
◍ Aquaporins.
Answer: A family of water channel proteins that provide permeability to
water
◍ STEP 1.
Answer: Initial drug research is conducted
◍ Factors Affecting Fluid & Electrolyte Distribution.
Answer: - Diffusion- Active Transport- Osmosis- Filtration- Reabsorption
◍ What is Diffusion?.
Answer: PARTICLES move from HIGH --> LOW solute conc.- DIffusion =
HIgh
◍ STEP 2.
Answer: Preclinical studies in cultured cells, living tissue, and species of
animals are performed
◍ What is Osmosis?.
Answer: WATER moves from LOW --> HIGH solute conc.- OsMOsis =
LOW
◍ Water Movement Between Plasma and Interstitial Fluid.
Answer: - Starling Hypothesis- Forces FAVORING Filtration- Forces
OPPOSING Filtration
◍ Starling Hypothesis.
Answer: Net filtration is equal to the forces favoring filtration minus the
forces opposing filtration
◍ STEP 3.
SCRIPT 2026 QUESTIONS WITH
SOLUTIONS GRADED A+
◍ What are body fluids divided into?.
Answer: Fluid compartments
◍ What does effective use of drugs by a health care team depend on?.
Answer: Being able to apply knowledge related to:- Anatomy & Physiology-
Pathophysiology- Chemistry- Microbiology- CJ- Nursing Process
◍ How many Fluid Compartments are there? What are they?.
Answer: 2 Fluid compartments:1. Intracellular (ICF)2. Extracellular (ECF)
◍ ICF Total Body Fluid.
Answer: 2/3 total body fluid INSIDE the cells
◍ ECF Total Body Fluid.
Answer: 1/3 total body fluid inside the OUTSIDE the cells
◍ Canadian Drug Regulations.
Answer: Created to protect public from drug misuse and provide mechanism
for quality assurance for safety & efficacy
◍ What is ECF composed of?.
Answer: Composed of plasma and ICF:- interstitial fluid- intravascular
fluid- cerebrospinal fluid (CSF)- lymphatic, synovial, intestinal, biliary,
hepatic, pancreatic, pleural, peritoneal, pericardial, and intraocular fluids-
sweat- urine
◍ Distribution of Body Fluids?.
Answer: Fluid moves continuously between ICF and ECF compartments
through semi-permeable cell membranes
,◍ Intracellular Fluid Compartment.
Answer: - Cells: 25 L- 40% of body weight
◍ Health Products and Food Branches (HPFB).
Answer: HPFB of Health Canada is responsible for ensuring safety and
quality of drugs, biologics, and natural health products
◍ Extracellular Fluid Compartment.
Answer: - Interstitial Fluid: 12 L- Plasma: 3 L- 20% of body weight
◍ What separates the Cells and the Interstitial fluid (ICF and ECF).
Answer: Plasma Membrane
◍ What separates Interstitial fluid and Plasma (ECF and ECF).
Answer: Capillary Membrane
◍ Total Body Water: Newborn.
Answer: 70-80% of body weight
◍ Total Body Water: Childhood.
Answer: 60-65% of body weight
◍ What is the standard set by?.
Answer: Food and Drug Act and Regulations
◍ Total Body Water: Adults.
Answer: 50-60% of body weight
◍ Total Body Water: Older Adults.
Answer: Percent declines with age
◍ Who has greater percentage of body water: Men or Women?.
Answer: Men have greater percentage of body water compared with women
◍ Who is at a higher risk for dehydration? Why?.
Answer: Newborns - do not concentrate urine as effectively and have a high
rate of metabolism; high rate of evaporation; large body surface area
compared to their body volume; low residual volume in lungs; not mature
yetSigns to watch for: sleepiness, sunken eyes, skin turgor, less wet diapers
, ◍ How many steps are there for approval of drugs marketed in Canada?.
Answer: 8 steps
◍ Water Movement Between ICF and ECF.
Answer: - Osmolality- Osmotic forces- Sodium for ECF- Potassium for ICF-
Aquaporins
◍ Aquaporins.
Answer: A family of water channel proteins that provide permeability to
water
◍ STEP 1.
Answer: Initial drug research is conducted
◍ Factors Affecting Fluid & Electrolyte Distribution.
Answer: - Diffusion- Active Transport- Osmosis- Filtration- Reabsorption
◍ What is Diffusion?.
Answer: PARTICLES move from HIGH --> LOW solute conc.- DIffusion =
HIgh
◍ STEP 2.
Answer: Preclinical studies in cultured cells, living tissue, and species of
animals are performed
◍ What is Osmosis?.
Answer: WATER moves from LOW --> HIGH solute conc.- OsMOsis =
LOW
◍ Water Movement Between Plasma and Interstitial Fluid.
Answer: - Starling Hypothesis- Forces FAVORING Filtration- Forces
OPPOSING Filtration
◍ Starling Hypothesis.
Answer: Net filtration is equal to the forces favoring filtration minus the
forces opposing filtration
◍ STEP 3.
