Refinement refers to.....
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modifying experiments or procedures to reduce the potential for pain or
distress to the animals
What does IACUC stand for?
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Institutional Animal Care and Use Committee
USDA stands for
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United States Department of Agriculture
examples of reduction
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Limiting group sizes to the minimum needed to obtain statistically
significant data
Performing multiple experiments simultaneously, so that the same control
group can be used for all the experiments
Sharing tissues and animals that do not meet study criteria (for example,
with the wrong genetic profile) with other investigators, so that additional
animals are not needed
Designing experiments, so that animals serve as their own controls
Using newer instrumentation that improves precision and reduces the
number of animals needed per data point
does a non survival sx always call for aseptic technique?
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nope
PHS Policy two parts
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, PHS policy on humane care and use of lab animals
Guide for the care and use of lab animals (the Guide)
Which of the following is false concerning prolonged restraint of animals?
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It can be justified simply as a convenience for the research staff.
Which of the following is true concerning exsanguination?
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It is a technique that can be appropriately used to ensure death in
unconscious animals.
Which of the following is an example of reduction?
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The use of common control groups during simultaneous experiments to
limit the number of control animals needed.
minor sx examples
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modifying experiments or procedures to reduce the potential for pain or
distress to the animals
What does IACUC stand for?
Give this one a try later!
Institutional Animal Care and Use Committee
USDA stands for
,Give this one a try later!
United States Department of Agriculture
examples of reduction
Give this one a try later!
Limiting group sizes to the minimum needed to obtain statistically
significant data
Performing multiple experiments simultaneously, so that the same control
group can be used for all the experiments
Sharing tissues and animals that do not meet study criteria (for example,
with the wrong genetic profile) with other investigators, so that additional
animals are not needed
Designing experiments, so that animals serve as their own controls
Using newer instrumentation that improves precision and reduces the
number of animals needed per data point
does a non survival sx always call for aseptic technique?
Give this one a try later!
nope
PHS Policy two parts
Give this one a try later!
, PHS policy on humane care and use of lab animals
Guide for the care and use of lab animals (the Guide)
Which of the following is false concerning prolonged restraint of animals?
Give this one a try later!
It can be justified simply as a convenience for the research staff.
Which of the following is true concerning exsanguination?
Give this one a try later!
It is a technique that can be appropriately used to ensure death in
unconscious animals.
Which of the following is an example of reduction?
Give this one a try later!
The use of common control groups during simultaneous experiments to
limit the number of control animals needed.
minor sx examples
