BME 302 FINAL CERTIFICATION
SCRIPT 2026 QUESTIONS WITH
SOLUTIONS GRADED A+
◍ Mach Number.
Answer: -if Ma <<1, incompressible -if Ma >>1, density controls Ma= flow
speed/speed of sound
◍ what does biomaterial success depend on.
Answer: host tissue and biological response to implantation- adverse rxns
can cause scar tissue or allergic response
◍ Peclet Number.
Answer: -convection/diffusion -Pe PUSHES (big Pe, the flow carries)
◍ fibroblasts.
Answer: - connective tissue cells- deposit collagen- stromal cells and among
other ECM proteins
◍ No-Slip Condition.
Answer: -velocity is 0 at the wall -Dirichlet condition
◍ Box Heat Diffusion.
Answer: Need to explain more here
◍ Number of Conditions.
Answer: 2D-> 4 sides, 1 initial condition and 4 boundary conditions3D-> 6
sides, 6 boundary conditions
◍ inflammation.
Answer: - redness, swelling, heat, pain- sets in motion a series of events to
heal the implant site through tissue replacement by regenerating cell,
forming scar tissue, or both
, ◍ foreign body reaction.
Answer: - implanting a biomaterial causes injury and provokes wound
healing response- presence of biomaterial as a foreign body is recognized by
immune cells and leads to reaction
◍ Incompatible boundary conditions.
Answer: -corners have different values
◍ Forward Euler Local Error.
Answer: O(h^2)
◍ Forward Euler Global Error.
Answer: O(h)
◍ Backward Euler Global Error.
Answer: O(h)
◍ four steps in foreign body reaction.
Answer: - protein adsorption (minutes)- acute inflammation (hours/days)-
chronic inflammation (weeks)- fibrosis (months)responding cells do not see
the material, but the proteins absorbed on it
◍ Vroman effect.
Answer: - process of competitive protein adsorption on biomaterial surface
by blood serum proteins- single protein solutions depend on protein and
surface properties, but could be slow/fast reversible/irreversible- multiple
soluble proteins: rapidly adsorbing protein with low surface affinity can be
displaced by slow adsorbing protein with high affinity, low MW proteins
can be displaced by high MW proteins, OPPOSITE NEVER OCCURS
◍ Heun's Method Local Error.
Answer: O(h^3)
◍ levels of protein structure and interactions.
Answer: - primary structure- secondary structure- tertiary structure-
quaternary structure
◍ Crank-Nicolson.
SCRIPT 2026 QUESTIONS WITH
SOLUTIONS GRADED A+
◍ Mach Number.
Answer: -if Ma <<1, incompressible -if Ma >>1, density controls Ma= flow
speed/speed of sound
◍ what does biomaterial success depend on.
Answer: host tissue and biological response to implantation- adverse rxns
can cause scar tissue or allergic response
◍ Peclet Number.
Answer: -convection/diffusion -Pe PUSHES (big Pe, the flow carries)
◍ fibroblasts.
Answer: - connective tissue cells- deposit collagen- stromal cells and among
other ECM proteins
◍ No-Slip Condition.
Answer: -velocity is 0 at the wall -Dirichlet condition
◍ Box Heat Diffusion.
Answer: Need to explain more here
◍ Number of Conditions.
Answer: 2D-> 4 sides, 1 initial condition and 4 boundary conditions3D-> 6
sides, 6 boundary conditions
◍ inflammation.
Answer: - redness, swelling, heat, pain- sets in motion a series of events to
heal the implant site through tissue replacement by regenerating cell,
forming scar tissue, or both
, ◍ foreign body reaction.
Answer: - implanting a biomaterial causes injury and provokes wound
healing response- presence of biomaterial as a foreign body is recognized by
immune cells and leads to reaction
◍ Incompatible boundary conditions.
Answer: -corners have different values
◍ Forward Euler Local Error.
Answer: O(h^2)
◍ Forward Euler Global Error.
Answer: O(h)
◍ Backward Euler Global Error.
Answer: O(h)
◍ four steps in foreign body reaction.
Answer: - protein adsorption (minutes)- acute inflammation (hours/days)-
chronic inflammation (weeks)- fibrosis (months)responding cells do not see
the material, but the proteins absorbed on it
◍ Vroman effect.
Answer: - process of competitive protein adsorption on biomaterial surface
by blood serum proteins- single protein solutions depend on protein and
surface properties, but could be slow/fast reversible/irreversible- multiple
soluble proteins: rapidly adsorbing protein with low surface affinity can be
displaced by slow adsorbing protein with high affinity, low MW proteins
can be displaced by high MW proteins, OPPOSITE NEVER OCCURS
◍ Heun's Method Local Error.
Answer: O(h^3)
◍ levels of protein structure and interactions.
Answer: - primary structure- secondary structure- tertiary structure-
quaternary structure
◍ Crank-Nicolson.
