PHARMACOLOGY
MODULE 7 EXAM
Actual Questions with Answers
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,7.1 What type of gastric acid is released by the parietal cells?
Correct Answer:
Hydrochloric acid / HCl
7.2 Select the substance below that is a major stimulator for the release of gastric
juices.
A. Acetylcholine
B. HCl
C. Substance P
D. Serotonin
Correct Answer:
A. Acetylcholine
Rationale:
Acetylcholine stimulates gastric secretion by acting on receptors involved in the release
of gastric juices. HCl is the acid product released, not the main stimulator.
7.3 Describe the role of gastrin in the release of gastric acid.
Correct Answer:
Gastrin binds to receptors on enterochromaffin-like cells and parietal cells, which
stimulates histamine release and promotes hydrochloric acid secretion.
7.4 Name the type of bacteria that is the primary cause of peptic ulcers.
Correct Answer:
Helicobacter pylori / H. pylori
,7.5 A patient has been diagnosed with a peptic ulcer not caused by bacteria. Select the
drug below least likely to have played a part in causing this ulcer.
A. Ibuprofen
B. Aspirin
C. Amoxicillin
D. Naproxen
Correct Answer:
C. Amoxicillin
Rationale:
Ibuprofen, aspirin, and naproxen are NSAIDs that can contribute to ulcer formation by
reducing protective prostaglandins in the stomach. Amoxicillin is an antibiotic and is not
typically associated with causing peptic ulcers.
7.6 True or False. The pain associated with duodenal ulcers is often relieved with food.
Correct Answer:
True
Rationale:
Duodenal ulcer pain is often relieved temporarily by food because food buffers stomach
acid. Pain may return later as the stomach empties and acid exposure increases.
7.7 What does GERD stand for?
Correct Answer:
Gastroesophageal reflux disease
7.8 Select the TRUE statement regarding GERD.
A. Synonymous with occasional heartburn
B. LES loosens
C. Symptoms cannot be impacted by diet changes
D. H2 blockers are the most effective treatment
, Correct Answer:
B. LES loosens
Rationale:
GERD occurs when the lower esophageal sphincter, or LES, relaxes or weakens, allowing
gastric contents to reflux into the esophagus.
7.9 In reference to the treatment of peptic ulcers caused by H. pylori, what three
classes of medications are most often used in the treatment regimens?
Correct Answer:
Antibiotics, bismuth salts, and proton pump inhibitors / PPIs
7.10 Select the antibiotic that is not recommended for the treatment of H. pylori.
A. Amoxicillin
B. Levofloxacin
C. Clarithromycin
D. Tetracycline
Correct Answer:
B. Levofloxacin
Rationale:
Common H. pylori regimens typically include antibiotics such as amoxicillin,
clarithromycin, metronidazole, or tetracycline along with acid suppression. Levofloxacin
is not a routine first-line option in this context.
7.11 True or False: "Quadruple therapy" refers to a treatment regimen for peptic ulcers
including antibiotics, bismuth, and H2 antagonists.
Correct Answer:
False