PHARMACOLOGY
FINAL EXAM
Actual Questions with Answers
Portage Learning
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• This Exam Review Includes Rationales
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,1. Match the route of oral administration to its indication:
Table
Route of Administration Indication
Oral Safest and most convenient
Transdermal Provides continuous absorption
Intravenous Used in emergency situations
Vaginal Given as creams and suppositories
2. The drug buprenorphine is given to decrease withdrawal symptoms in opioid users.
It binds to opioid receptors in the brain but without the strength of other drugs.
Buprenorphine is an:
Correct Answer:
Partial agonist
Rationale:
Buprenorphine activates opioid receptors but produces a weaker response than a full
agonist, which helps reduce withdrawal symptoms while lowering the risk of full opioid-
like effects.
3. Aging can lead to decreased intestinal blood flow, surface area, and motility, which
can slow the onset of action of an oral drug. Which pharmacokinetic process is
affected in this scenario?
, Correct Answer:
Absorption
Rationale:
Absorption refers to the movement of a drug from the site of administration into the
bloodstream. Reduced intestinal blood flow, surface area, and motility can delay oral
drug absorption.
4. When the combined effect of 2 drugs is greater than the sum of their individual
effects it is referred to as:
Correct Answer:
Synergism
Rationale:
Synergism occurs when two drugs taken together produce a greater effect than
expected from adding their individual effects.
5. T/F — If statement is false, explain why: Schedule IV drugs have high abuse
potential and no accepted medical use.
Correct Answer:
False
Explanation:
Schedule IV drugs have a lower abuse potential compared with Schedule I, II, and III
drugs and have accepted medical uses.
6. Michael is a 2-year-old male with a history of liver cirrhosis problem caused by
biliary atresia. While on a family vacation, Michael developed a fever, and his parents
found children's Motrin as the only antipyretic option at the hotel convenience shop.
Is this appropriate for Michael? Explain why.
Correct Answer:
No. Michael's doctor should be consulted because of his liver cirrhosis.