BIOCHEMISTRY EXAM 1 (MULTIPLE CHOICE + FORMULAS) QUESTIONS AND CORRECT VERIFIED ANSWERS

BIOCHEMISTRY EXAM 1 (MULTIPLE
CHOICE + FORMULAS) QUESTIONS AND
CORRECT VERIFIED ANSWERS
ApproximatelyA2whatA2percentageA2ofA2theA2humanA2genomeA2encodesA2forA2protein?A2-
A2Ans--3%


WhatA2pairsA2ofA2atomsA2inA2basesA2areA2involvedA2inA2hydrogenA2bonds?A2
A)A2N-HA2andA2O-H
B)A2N-HA2andA2S-H
C)A2O-HA2andA2P-O
D)A2AllA2ofA2theA2above
E)A2NoneA2ofA2theA2aboveA2-A2Ans--A)A2N-HA2andA2O-H

TheA2structureA2ofA2DNAA2describedA2byA2WatsonA2andA2CrickA2included
A)A2aA2doubleA2helix
B)A2theA2sugarA2phosphateA2backboneA2alignedA2inA2theA2centerA2ofA2theA2helix
C)A2theA2baseA2pairsA2thatA2areA2stackedA2onA2theA2insideA2ofA2theA2doubleA2helix
D)A2AA2andA2B
E)A2AA2andA2CA2-A2Ans--E)A2AA2andA2C

WhatA2twoA2propertiesA2ofA2waterA2areA2importantA2forA2biologicalA2interactions?A2-A2Ans--
TheA2polarityA2ofA2water
TheA2cohesiveA2propertiesA2ofA2water

HowA2manyA2hydrogenA2bondsA2areA2formedA2betweenA2AA2andA2T?A2-A2Ans--2

WhatA2givesA2proteinsA2aA2dominantA2roleA2inA2biochemistry?A2-A2Ans--
TheirA2abilityA2toA2spontaneouslyA2foldA2intoA2complexA2three-dimensionalA2structures

WhichA2ofA2theA2followingA2isA2consideredA2aA2noncovalentA2bond?
A)A2ElectrostaticA2interactions
B)A2HydrogenA2bonds
C)A2VanA2derA2WaalsA2interactions
D)A2AllA2ofA2theA2above
E)A2NoneA2ofA2theA2aboveA2-A2Ans--D)A2AllA2ofA2theA2above

TheA2FirstA2LawA2ofA2ThermodynamicsA2statesA2what?A2-A2Ans--
TheA2totalA2energyA2ofA2aA2systemA2andA2itsA2surroundingsA2isA2constant

TheA2SecondA2LawA2ofA2ThermodynamicsA2statesA2what?A2-A2Ans--
TheA2totalA2entropyA2ofA2aA2systemA2andA2itsA2surroundingsA2alwaysA2increasesA2forA2aA2s
pontaneousA2process

, ListA2atomsA2commonlyA2foundA2inA2biologicalA2moleculesA2thatA2areA2oftenA2hydrogen-
bondA2acceptors.A2-A2Ans--Oxygen
Nitrogen

WhatA2isA2theA2[A-]/
[HA]A2ratioA2whenA2theA2weakA2acidA2isA2inA2aA2solutionA2oneA2pHA2unitA2belowA2itsA2pKa?
A2-A2Ans--1:10


IfA2aA2particularA2reactionA2hasA2aA2negativeA2delta-
GA2(GibbsA2FreeA2Energy),A2isA2itA2likelyA2toA2occur?A2-A2Ans--Yes,A2itA2isA2spontaneous

WhatA2isA2theA2[H+]A2concentrationA2inA2aA2urineA2sampleA2thatA2hasA2aA2pHA2ofA28?A2-
A2Ans--10^-8A2M


WhatA2happensA2toA2nonpolarA2moleculesA2inA2water?A2-A2Ans--
TheyA2aggregateA2together

WhatA2typeA2ofA2chiralA2aminoA2acidsA2isA2foundA2inA2proteins?A2-A2Ans--L

WhatA2isA2anotherA2nameA2forA2dipolarA2molecules?A2-A2Ans--Zwitterions

WhenA2aA2peptideA2bondA2isA2formed,A2whatA2moleculeA2isA2alsoA2made?A2-A2Ans--Water

WriteA2theA2name,A2threeA2letterA2code,A2andA2singleA2letterA2codeA2forA2theA2aminoA2acidA
2forA2theA2following:
A)A2theA2aminoA2acidA2withA2aA2pKaA2nearA2neutralA2pH
B)A2disulfideA2bondsA2areA2formedA2byA2pairsA2ofA2whichA2aminoA2acid
C)A2thisA2aminoA2acidA2residueA2disruptsA2theA2alpha-
helixA2becauseA2itsA2sideA2chainA2containsA2aA2uniqueA2ringA2structureA2thatA2restrictsA2bo
ndA2rotationA2-A2Ans--A)A2Histidine,A2His,A2H
B)A2Cysteine,A2Cys,A2C
C)A2Proline,A2Pro,A2P

WhatA2determinesA2aA2protein'sA2function?A2-A2Ans--Structure

WhatA2isA2theA2nameA2ofA2theA2plotA2thatA2allowsA2oneA2toA2investigateA2theA2likelyA2orient
ationA2ofA2certainA2aminoA2acidA2pairs?A2-A2Ans--Ramachandran

WhatA2typeA2ofA2structureA2includesA2alpha-helices,A2beta-sheets,A2andA2turns?A2-A2Ans--
SecondaryA2structure

WhatA2typeA2ofA2proteinA2structureA2developsA2whenA2twoA2proteinsA2combineA2toA2formA2
oneA2largerA2protein?A2-A2Ans--QuaternaryA2structure

WhatA2isA2responsibleA2forA2theA2tertiaryA2structureA2ofA2proteins?A2-A2Ans--
InteractionsA2betweenA2aminoA2acidA2sideA2chains