Maryville Patho NURS 611 Exam 2. dr. Wunderlich ||
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the most abundant class of innumoglobulins; they constitute
80-85% and account for the most protective activity against
infections
Maternal IgG crosses into placenta and can be found in blood
of the fetus - ANSWER-IgG
found in bodily secretions as dimers anchored together
through a J chain and "secretory piece". The secretory piece
may function to protect the Ig against degradation by enzymes.
These are produced by cells in mucous membranes - ANSWER-
IgA
the largest of the immunoglobulins. The FIRST antibody
produced during the initial/primary response to antigen.
Synthsized early in neonatal life and the synthesis may be
increased as a response to infection in utero; it is a pentemere-
the initial most important responder to infection - ANSWER-IgM
,the least concentrated of the Ig in circulation. Appears to have
very specialized functions as a mediator of many common
allergic responses and in the defense against parasitic
infections - ANSWER-IgE
chronic, multisystem, inflammatory disease that is one of the
most common, complex, and serious autoimmune disorders -
ANSWER-Systemis Lupus Erythmatosus (SLE)
swelling, commonly seen after TBI can lead to dangerous
___________ which can cause collateral dysfunction (Reason
to watch output during DI because ADH is not secreted-thus
polyuria) - ANSWER-increases intracranial pressure
number 1 injury to the brain - ANSWER-hypoxia
acute, sudden onset, common during hospitalization, lasts
hours to weeks, agitation, withdrawn/depression behavior,
disoriented thoughts, hallucinations - ANSWER-delerium
chronic, insidious or gradual onset, slow decline, can lasts
months to years, attention and orientation are often intact early
and impaired late - ANSWER-dementia
condition diagnosed by ruling out other possibilities -
ANSWER-alzheimers
hemiplegia orhemiparesis greater in face and arm than leg,
contralateral loss in same distribution as motor loss,
,expressive disorder with anomia, contralateral homonymous
hemianoplopia (left vision is intact), cheyne-stokes
respirations, occasional mydriasis, little to no sensory loss -
ANSWER-signs and symptoms of stroke (middle cerebral
artery)
GBS is caused by a recent bacterial or viral infection; MS is not
caused by a previous infection - ANSWER-difference between
guillain-barre syndrome and multiple sclerosis
first MS event occasionally happens when? - ANSWER-during
pregnancy
a chronic inflammatory disease involving degeneration of CNS
myelin, scarring or formation of plaque, loss of axons. It is
caused by an autoimmune response to self-antigen in
genetically susceptible individuals - ANSWER-MS
initially 90% of persons present with a relapsing, remitting
course; 10% present with a primary progressive course; 90%
develop a progressive course in 10-20 years after onset of the
disease; however, once walking problems develop, disease
progression occurs quickly regardless of disease type -
ANSWER-MS clinical manifestations
inflammatory changes in the CNS increase, and loss of brain
volume progresses more rapidly. the demyelination disrupts
sodium, calcium, and potassium ion channels and calcium
influx is proinflammatory and neurotoxic. Activated microglia
, and macrophages release nitric oxide and free radicals. -
ANSWER-MS disease progression
allergies - ANSWER-type I hypersensitivity
antibody-dependent; ex: hyperthyroidism = antibody stimulates
thyroid cells to produce thyroxine - ANSWER-type II
hypersensitivity
universal donor blood type; can be given to a, b, or ab -
ANSWER-O
universal recipient blood type, can receive o, a, or b - ANSWER-
AB
caused by immune complexes ; primary difference between
this hypersensitivity and type II hypersensitivity reactions are
that the antibody binds to soluble antigen causing the complex
to deposit in the tissues
ex: raynaud phenomenon - ANSWER-type III hypersensitivity
delayed reaction; ex: graft rejection, contact dermatitis from
poison ivy - ANSWER-type IV hypersensitivity
a chronic, multisystem, inflammatory disease; it is the most
common, complex, and serious of the autoimmune disorders -
ANSWER-SLE
Most Recent Exam 2026/27 || Actual Complete Real
Exam Questions And Correct Detailed Answers
(Verified Answers) Already Graded A+ | Guaranteed
Success!! Newest Exam | Just Released!! | Instant
Download
the most abundant class of innumoglobulins; they constitute
80-85% and account for the most protective activity against
infections
Maternal IgG crosses into placenta and can be found in blood
of the fetus - ANSWER-IgG
found in bodily secretions as dimers anchored together
through a J chain and "secretory piece". The secretory piece
may function to protect the Ig against degradation by enzymes.
These are produced by cells in mucous membranes - ANSWER-
IgA
the largest of the immunoglobulins. The FIRST antibody
produced during the initial/primary response to antigen.
Synthsized early in neonatal life and the synthesis may be
increased as a response to infection in utero; it is a pentemere-
the initial most important responder to infection - ANSWER-IgM
,the least concentrated of the Ig in circulation. Appears to have
very specialized functions as a mediator of many common
allergic responses and in the defense against parasitic
infections - ANSWER-IgE
chronic, multisystem, inflammatory disease that is one of the
most common, complex, and serious autoimmune disorders -
ANSWER-Systemis Lupus Erythmatosus (SLE)
swelling, commonly seen after TBI can lead to dangerous
___________ which can cause collateral dysfunction (Reason
to watch output during DI because ADH is not secreted-thus
polyuria) - ANSWER-increases intracranial pressure
number 1 injury to the brain - ANSWER-hypoxia
acute, sudden onset, common during hospitalization, lasts
hours to weeks, agitation, withdrawn/depression behavior,
disoriented thoughts, hallucinations - ANSWER-delerium
chronic, insidious or gradual onset, slow decline, can lasts
months to years, attention and orientation are often intact early
and impaired late - ANSWER-dementia
condition diagnosed by ruling out other possibilities -
ANSWER-alzheimers
hemiplegia orhemiparesis greater in face and arm than leg,
contralateral loss in same distribution as motor loss,
,expressive disorder with anomia, contralateral homonymous
hemianoplopia (left vision is intact), cheyne-stokes
respirations, occasional mydriasis, little to no sensory loss -
ANSWER-signs and symptoms of stroke (middle cerebral
artery)
GBS is caused by a recent bacterial or viral infection; MS is not
caused by a previous infection - ANSWER-difference between
guillain-barre syndrome and multiple sclerosis
first MS event occasionally happens when? - ANSWER-during
pregnancy
a chronic inflammatory disease involving degeneration of CNS
myelin, scarring or formation of plaque, loss of axons. It is
caused by an autoimmune response to self-antigen in
genetically susceptible individuals - ANSWER-MS
initially 90% of persons present with a relapsing, remitting
course; 10% present with a primary progressive course; 90%
develop a progressive course in 10-20 years after onset of the
disease; however, once walking problems develop, disease
progression occurs quickly regardless of disease type -
ANSWER-MS clinical manifestations
inflammatory changes in the CNS increase, and loss of brain
volume progresses more rapidly. the demyelination disrupts
sodium, calcium, and potassium ion channels and calcium
influx is proinflammatory and neurotoxic. Activated microglia
, and macrophages release nitric oxide and free radicals. -
ANSWER-MS disease progression
allergies - ANSWER-type I hypersensitivity
antibody-dependent; ex: hyperthyroidism = antibody stimulates
thyroid cells to produce thyroxine - ANSWER-type II
hypersensitivity
universal donor blood type; can be given to a, b, or ab -
ANSWER-O
universal recipient blood type, can receive o, a, or b - ANSWER-
AB
caused by immune complexes ; primary difference between
this hypersensitivity and type II hypersensitivity reactions are
that the antibody binds to soluble antigen causing the complex
to deposit in the tissues
ex: raynaud phenomenon - ANSWER-type III hypersensitivity
delayed reaction; ex: graft rejection, contact dermatitis from
poison ivy - ANSWER-type IV hypersensitivity
a chronic, multisystem, inflammatory disease; it is the most
common, complex, and serious of the autoimmune disorders -
ANSWER-SLE
