NURS 660 PSYCHOPHARMACOLOGY EXAM 2 | COMPLETE
QUESTIONS WITH EXPERT SOLUTIONS| 2026 LATEST UPDATED| A+
Which medication has the SE of losing hair - (answer)Lithium
The pt is bipolar, and had a partial response to depakote and now is going to be augmented with
an atypical antipsychotic, the effects of atypical antipsychotics in non-psychotic mania may be
due to what - (answer)indirect effect on glutamate release via 5H2A antagonism
A pt has had some success with his current antidepression medication, has tried many different
antidepressants, so you decide to augment with L-methyl-folate. What is the hypothesis behind L
methyl Folate boosting the therapeutic efficacy of antidepressants...what is the MOA? -
(answer)boosts monamine neurotransmitter function in bipolar disorder
You have a pt that has been very depressed and has insomnia problems with concentrations,
weight loss and SI. You start them on an AD and his symptoms have abated, however which of
the following symptoms is the most likely to be residual following the successful tx of other
symptoms? - (answer)insomnia
Which class of antidepressant have a lower incidence of sexual SE? What medication is used in
the tx of BP/mania and is used in prophylaxis as well as antidepressant augmentation? Which
medication is this? - (answer)Wellbutrin
,What medication is a very potent CYP450 inhibitor and can dangerously elevate lamotrigine? -
(answer)Valproate
Which class of antidepressant has the worst discontinuation syndrome? - (answer)Cymbalta
You have a female pt complaining of lactating and is not pregnant w/ no children. She has been
taking risperidone. Which medication would you avoid if you were to switch her to another
med?" - (answer)Paliperidone
A pt is on Prozac and it has stopped working. Patient has been on many other antidepressants and
wants to try an MAOI now. How long do you need to stop Prozac before starting MAOI? -
(answer)5-6 weeks
What neurotransmitter are affected by TCAs? - (answer)Serotonin, dopamine, norepinorphrenie,
5HT
What TCA medication should absolutely not be used in combination with any other MAOI? -
(answer)chlomipramine
,Please know what is the most potent property of trazodone by what neurotransmitter? -
(answer)SEDATION; 5H2A
Patient prescribed Clomipramine suddenly stops taking medication. What side effects could be
shown? - (answer)Cardiovascular, coma, seizure, death
What neurotransmitters are effected by tricyclic antidepressants - (answer)increase levels of
norepinephrine and serotonin, and block the action of acetylcholine
You have a patient that has rapid cycling bipolar disorder. Which combination that should be
given together? - (answer)lithium and lurasideon, lamotrigine and quetiapine
You have a patient that has rapid cycling bipolar disorder. Which combination that should not be
given together? - (answer)carbamazepine lurasidone, valproate and quetiapine
What medication is safe to take with MAOI - (answer)Lithium
What are the two factors that are most useful for determining if a presenting depressive episode
is unipolar or bipolar? - (answer)family history, input from someone close
, The only atypical approved for bipolar depression - (answer)quetiapine
A 28 yr old woman presents with depression. She has been treated with manic episode before
however is not taking medication. Whhat meds work the best to tx bipolar depression? -
(answer)Lamictal
Does clozapine increase TCA A levels? - (answer)true
Cigarette smoking decrease TCA levels - (answer)false
How many half-lives do you have to wait before you can initiate MAOI inhibitor medication -
(answer)5 half lives
Which antidepressant and drug class has a higher incident of gaining weight out of all the
Antidepressants - (answer)paxil: SSRI
Which medication can cause hypothyroidism? - (answer)Lithium
QUESTIONS WITH EXPERT SOLUTIONS| 2026 LATEST UPDATED| A+
Which medication has the SE of losing hair - (answer)Lithium
The pt is bipolar, and had a partial response to depakote and now is going to be augmented with
an atypical antipsychotic, the effects of atypical antipsychotics in non-psychotic mania may be
due to what - (answer)indirect effect on glutamate release via 5H2A antagonism
A pt has had some success with his current antidepression medication, has tried many different
antidepressants, so you decide to augment with L-methyl-folate. What is the hypothesis behind L
methyl Folate boosting the therapeutic efficacy of antidepressants...what is the MOA? -
(answer)boosts monamine neurotransmitter function in bipolar disorder
You have a pt that has been very depressed and has insomnia problems with concentrations,
weight loss and SI. You start them on an AD and his symptoms have abated, however which of
the following symptoms is the most likely to be residual following the successful tx of other
symptoms? - (answer)insomnia
Which class of antidepressant have a lower incidence of sexual SE? What medication is used in
the tx of BP/mania and is used in prophylaxis as well as antidepressant augmentation? Which
medication is this? - (answer)Wellbutrin
,What medication is a very potent CYP450 inhibitor and can dangerously elevate lamotrigine? -
(answer)Valproate
Which class of antidepressant has the worst discontinuation syndrome? - (answer)Cymbalta
You have a female pt complaining of lactating and is not pregnant w/ no children. She has been
taking risperidone. Which medication would you avoid if you were to switch her to another
med?" - (answer)Paliperidone
A pt is on Prozac and it has stopped working. Patient has been on many other antidepressants and
wants to try an MAOI now. How long do you need to stop Prozac before starting MAOI? -
(answer)5-6 weeks
What neurotransmitter are affected by TCAs? - (answer)Serotonin, dopamine, norepinorphrenie,
5HT
What TCA medication should absolutely not be used in combination with any other MAOI? -
(answer)chlomipramine
,Please know what is the most potent property of trazodone by what neurotransmitter? -
(answer)SEDATION; 5H2A
Patient prescribed Clomipramine suddenly stops taking medication. What side effects could be
shown? - (answer)Cardiovascular, coma, seizure, death
What neurotransmitters are effected by tricyclic antidepressants - (answer)increase levels of
norepinephrine and serotonin, and block the action of acetylcholine
You have a patient that has rapid cycling bipolar disorder. Which combination that should be
given together? - (answer)lithium and lurasideon, lamotrigine and quetiapine
You have a patient that has rapid cycling bipolar disorder. Which combination that should not be
given together? - (answer)carbamazepine lurasidone, valproate and quetiapine
What medication is safe to take with MAOI - (answer)Lithium
What are the two factors that are most useful for determining if a presenting depressive episode
is unipolar or bipolar? - (answer)family history, input from someone close
, The only atypical approved for bipolar depression - (answer)quetiapine
A 28 yr old woman presents with depression. She has been treated with manic episode before
however is not taking medication. Whhat meds work the best to tx bipolar depression? -
(answer)Lamictal
Does clozapine increase TCA A levels? - (answer)true
Cigarette smoking decrease TCA levels - (answer)false
How many half-lives do you have to wait before you can initiate MAOI inhibitor medication -
(answer)5 half lives
Which antidepressant and drug class has a higher incident of gaining weight out of all the
Antidepressants - (answer)paxil: SSRI
Which medication can cause hypothyroidism? - (answer)Lithium
