116. What is linkage disequilibrium in reference to HLA haplotypes?
a. occurrence of HLA genes in the same haplotype more often than would be
expected based on the gene frequencies
b. displacement of HLA genes of different chromosomes
c. occurrence of HLA genes in the same haplotype less often than would be
expected based on the gene frequencies
d. recombination of HLA genes during meiosis
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a. occurrence of HLA genes in the same haplotype more often than would
be expected based on the gene frequencies
351. A temperature rise of 1 or more occurring in associated with a transfusion, with no
abnormal results in the transfusion reaction investigation, usually indicates which of
the following reactions
a. febrile
,b. circulatory overload
c. hemolytic
d. anaphylactic
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a. febrile
123. Which of the following immunoglobulins is most efficient at activating
complement via the classical pathway?
a. IgG2
b. IgG4
c. IgM
d. IgA
Give this one a try later!
c. IgM
367. An intraoperative strategy for patient blood management is
a. anemia assessment and treatment
b. autologous blood donation
c. acute normovolemic hemodilution
d. limiting phlebotomy related blood loss
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c. acute normovolemic hemodilution
,314. Platelet transfusions are of most value in treating:
a. hemolytic transfusion reaction
b. posttransfusion purpura
c. functional platelet abnormalities
d. immune thrombocytopenic purpura
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c. functional platelet abnormalities
276. Crossmatch results at the antiglobulin phase were negative. When 1 drop of check
cells was added, no agglutination was seen. The most likely explanation is that the:
a. red cells were overwashed
b. centrifuge speed was set too high
c. residual patient serum inactivated the AHG reagent
d. laboratorian did not add enough check cells
Give this one a try later!
c. residual patient serum inactivated the AHG reagent
211. A patient is a subgroup of A (Asub), Rh positive with anti-A1 in their serum. How
many units would you have to screen to find 1 unit that is compatible with the patient's
anti-A1?
a. 5
b. 10
c. 15
d. 20
Give this one a try later!
, a. 5
51. Leukocyte-Reduced Red Blood Cells are ordered for a newly diagnosed bone
marrow candidate. What is the best way to prepare this product?
a. crossmatch only CMV-seronegative units
b. irradiate the unit with 1,500 rads
c. wash the unit with saline prior to infusion
d. transfuse through a Log^3 leukocyte-removing filter
Give this one a try later!
d. transfuse through a Log^3 leukocyte-removing filter
Newly diagnosed bone marrow candidates are at great risk for severe
sequelae of CMV infections. Infection can best be reduced by using
leukocyte-reduction filters. CMV-seronegative units are rarely used since
leukocyte reducing via filtration is so effective. Washing does not remove
as many leukocytes as filtering.
121. What is the most common clinical incident that results in alloantibody production?
a. viral infection
b. solid tumor
c. red cell transfusion
d. autoimmune disease
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c. red cell transfusion
a. occurrence of HLA genes in the same haplotype more often than would be
expected based on the gene frequencies
b. displacement of HLA genes of different chromosomes
c. occurrence of HLA genes in the same haplotype less often than would be
expected based on the gene frequencies
d. recombination of HLA genes during meiosis
Give this one a try later!
a. occurrence of HLA genes in the same haplotype more often than would
be expected based on the gene frequencies
351. A temperature rise of 1 or more occurring in associated with a transfusion, with no
abnormal results in the transfusion reaction investigation, usually indicates which of
the following reactions
a. febrile
,b. circulatory overload
c. hemolytic
d. anaphylactic
Give this one a try later!
a. febrile
123. Which of the following immunoglobulins is most efficient at activating
complement via the classical pathway?
a. IgG2
b. IgG4
c. IgM
d. IgA
Give this one a try later!
c. IgM
367. An intraoperative strategy for patient blood management is
a. anemia assessment and treatment
b. autologous blood donation
c. acute normovolemic hemodilution
d. limiting phlebotomy related blood loss
Give this one a try later!
c. acute normovolemic hemodilution
,314. Platelet transfusions are of most value in treating:
a. hemolytic transfusion reaction
b. posttransfusion purpura
c. functional platelet abnormalities
d. immune thrombocytopenic purpura
Give this one a try later!
c. functional platelet abnormalities
276. Crossmatch results at the antiglobulin phase were negative. When 1 drop of check
cells was added, no agglutination was seen. The most likely explanation is that the:
a. red cells were overwashed
b. centrifuge speed was set too high
c. residual patient serum inactivated the AHG reagent
d. laboratorian did not add enough check cells
Give this one a try later!
c. residual patient serum inactivated the AHG reagent
211. A patient is a subgroup of A (Asub), Rh positive with anti-A1 in their serum. How
many units would you have to screen to find 1 unit that is compatible with the patient's
anti-A1?
a. 5
b. 10
c. 15
d. 20
Give this one a try later!
, a. 5
51. Leukocyte-Reduced Red Blood Cells are ordered for a newly diagnosed bone
marrow candidate. What is the best way to prepare this product?
a. crossmatch only CMV-seronegative units
b. irradiate the unit with 1,500 rads
c. wash the unit with saline prior to infusion
d. transfuse through a Log^3 leukocyte-removing filter
Give this one a try later!
d. transfuse through a Log^3 leukocyte-removing filter
Newly diagnosed bone marrow candidates are at great risk for severe
sequelae of CMV infections. Infection can best be reduced by using
leukocyte-reduction filters. CMV-seronegative units are rarely used since
leukocyte reducing via filtration is so effective. Washing does not remove
as many leukocytes as filtering.
121. What is the most common clinical incident that results in alloantibody production?
a. viral infection
b. solid tumor
c. red cell transfusion
d. autoimmune disease
Give this one a try later!
c. red cell transfusion