Pharm final study guide ACTUAL UPDATED QUESTIONS AND CORRECT
ANSWERS
Absorption Bioavailability, extent of drug absorption
Distribution Transport drug by bloodstream to its site of action
, Metabolism Biotransformation, biochemical alteration of drug into inactive metabolite, more
soluble compound, more potent active metabolite, or less active metabolite
Excretion Elimination of drugs from body: renal, biliary, & bowel excretion
Narrow therapeutic index Drug has small gap between dose of effectiveness & a toxic dose
Agonist Drug that binds to a receptor, triggering biological response mimicking the
body's natural chemicals
Antagonist Drug that binds to receptor and does not activate, but blocks/interferes with
action of natural substance
Adverse effect Harmful or unintended reaction from drug
Contraindication Symptoms/factors that deem a certain drug unsafe, condition that makes drug
harmful
Antidote for an opioid overdose Naloxone
Meds for neuropathic pain Gabapentin (Neurontin)
Nursing consideration for IV administration of Cipro Must be well diluted & given over 1 hr
Vancomycin - signs of toxicity Red Man's Syndrome, Ototoxicity & Nephrotoxicity
-flushing or itching of head, neck, face, upper trunk, hypotension, SOB, dizziness,
headache, chills, fever, CP
How do you assess effectiveness for Abs Monitor therapeutic & sub therapeutic responses; Monitor labs (WBC)
Adverse effects of antibiotics Allergy, Superinfection, Resistance, Toxicity
Signs of anaphylaxis Swelling of airway, face, throat, face, & tongue; Dyspnea: tight throat,
bronchospasm, laryngeal edema; Itching, decreased BP, tachycardia, loss of
consciousness, skin rash
-Give Epinephrine & Benadryl
Respiratory Acidosis pH below or = to 7.35 (acidic); PaCO2 above or = to 45; HCO3- below or = 22
Respiratory Alkalosis pH above or = to 7.45; PaCO2 below or = 36; HCO3 above or = 28
Rx to use as rescue inhaler Albuterol
Which inhaler to use 1st if patient is using more than 1 Inhale B2 agonist first
inhaler
Types of meds used to treat Heart Failure Beta blockers, ARBs, Ace inhibitors, Diuretic
Furosemide Loop diuretic
ANSWERS
Absorption Bioavailability, extent of drug absorption
Distribution Transport drug by bloodstream to its site of action
, Metabolism Biotransformation, biochemical alteration of drug into inactive metabolite, more
soluble compound, more potent active metabolite, or less active metabolite
Excretion Elimination of drugs from body: renal, biliary, & bowel excretion
Narrow therapeutic index Drug has small gap between dose of effectiveness & a toxic dose
Agonist Drug that binds to a receptor, triggering biological response mimicking the
body's natural chemicals
Antagonist Drug that binds to receptor and does not activate, but blocks/interferes with
action of natural substance
Adverse effect Harmful or unintended reaction from drug
Contraindication Symptoms/factors that deem a certain drug unsafe, condition that makes drug
harmful
Antidote for an opioid overdose Naloxone
Meds for neuropathic pain Gabapentin (Neurontin)
Nursing consideration for IV administration of Cipro Must be well diluted & given over 1 hr
Vancomycin - signs of toxicity Red Man's Syndrome, Ototoxicity & Nephrotoxicity
-flushing or itching of head, neck, face, upper trunk, hypotension, SOB, dizziness,
headache, chills, fever, CP
How do you assess effectiveness for Abs Monitor therapeutic & sub therapeutic responses; Monitor labs (WBC)
Adverse effects of antibiotics Allergy, Superinfection, Resistance, Toxicity
Signs of anaphylaxis Swelling of airway, face, throat, face, & tongue; Dyspnea: tight throat,
bronchospasm, laryngeal edema; Itching, decreased BP, tachycardia, loss of
consciousness, skin rash
-Give Epinephrine & Benadryl
Respiratory Acidosis pH below or = to 7.35 (acidic); PaCO2 above or = to 45; HCO3- below or = 22
Respiratory Alkalosis pH above or = to 7.45; PaCO2 below or = 36; HCO3 above or = 28
Rx to use as rescue inhaler Albuterol
Which inhaler to use 1st if patient is using more than 1 Inhale B2 agonist first
inhaler
Types of meds used to treat Heart Failure Beta blockers, ARBs, Ace inhibitors, Diuretic
Furosemide Loop diuretic
