Pharm II HESI Practice Questions 2026 | Questions
& Answers PDF
1. A patient has been on high-dose corticosteroids for several months and is
now experiencing side effects. If the physician decides to discontinue the
medication, what would be the most appropriate course of action?
Switch to a different medication without tapering.
Taper the dosage gradually over a period of time.
Stop the medication immediately to prevent further side effects.
Continue the medication until the side effects resolve.
2. Which of the following agents reduce mortality in HF?
Carvedilol (Coreg)
Lisinopril (Prinivil)
Aldactone (Spironolactone)
all of the above
3. Which medication may be prescribed for a patient who was admitted to the
hospital with a blood pressure of 220/138 mm Hg and diagnosed with a
hypertensive emergency?
Sodium nitroprusside (Nipride)
Atenolol (Tenormin)
Spironolactone (Aldactone)
Furosemide (Lasix)
4. Which of the following is true of tetracycline?
It should not be used in pregnant women or young children
, It can cause photosensitivity
Patients should avoid dairy products within 2 hours of taking it
None of the above
All of the above
5. Why should cefazolin be avoided in patients with a known allergy to
penicillin?
Cefazolin is an antiviral medication.
Cefazolin is only used for skin infections.
Cefazolin is a cephalosporin, which can have cross-reactivity with
penicillin.
Cefazolin is unrelated to penicillin and is safe for all patients.
6. Describe the significance of prescribing azithromycin for both chlamydia and
gonococcal infections in a single dose.
Azithromycin requires multiple doses for effectiveness.
Azithromycin is effective against both infections, allowing for
convenient treatment.
Azithromycin is used primarily for respiratory infections.
Azithromycin is only effective for chlamydia, not gonococcal
infections.
7. What is the recommended timing for taking pantoprazole?
Immediately before troublesome meals only
At least 1 hour before a meal
Immediately after meals
, Before or after meals as needed
8. Describe how Sildenafil (Viagra) can lead to hypotension in patients.
Sildenafil (Viagra) has no effect on blood pressure.
Sildenafil (Viagra) can cause vasodilation, leading to a decrease in
blood pressure.
Sildenafil (Viagra) increases heart rate, causing hypotension.
Sildenafil (Viagra) causes fluid retention, leading to hypotension.
9. One of your patients is started on verapamil (Calan). Before administering the
dose you check
Heart rate
Temperature
Weight
Urine output
10. What should be monitored alongside treatment with furosemide?
electrolytes and acid base balance
potassium levels
blood pressure
electrolytes and renal function
11. This is an expected adverse effect of penicillins and cephalosporins:
Renal disease
Nausea and diarrhea
, Candida infection
12. A nurse is caring for a client prescribed ferrous sulfate for the treatment of
anemia. Which of the following instructions should be included in client
teaching about this medication?
Take the medication on an empty stomach to maximize absorption
Notify your provider if your stool becomes dark green
Decrease dietary fiber intake while taking this medication
Take prescribed antacids at the same time as this medication
13. What is the primary instruction regarding the administration of risedronate?
Take at bedtime
Take with food
Take on an empty stomach
Take with a full glass of water
14. What are two potential reproductive effects of anabolic steroid use in
males?
Enhanced muscle growth and endurance
Improved fertility and sperm motility
Increased testosterone levels and libido
Testicular atrophy and low sperm count
15. Which of the following contraindications or warnings is appropriate for
tetracyclines?
"Avoid use in children or pregnant or nursing women"
& Answers PDF
1. A patient has been on high-dose corticosteroids for several months and is
now experiencing side effects. If the physician decides to discontinue the
medication, what would be the most appropriate course of action?
Switch to a different medication without tapering.
Taper the dosage gradually over a period of time.
Stop the medication immediately to prevent further side effects.
Continue the medication until the side effects resolve.
2. Which of the following agents reduce mortality in HF?
Carvedilol (Coreg)
Lisinopril (Prinivil)
Aldactone (Spironolactone)
all of the above
3. Which medication may be prescribed for a patient who was admitted to the
hospital with a blood pressure of 220/138 mm Hg and diagnosed with a
hypertensive emergency?
Sodium nitroprusside (Nipride)
Atenolol (Tenormin)
Spironolactone (Aldactone)
Furosemide (Lasix)
4. Which of the following is true of tetracycline?
It should not be used in pregnant women or young children
, It can cause photosensitivity
Patients should avoid dairy products within 2 hours of taking it
None of the above
All of the above
5. Why should cefazolin be avoided in patients with a known allergy to
penicillin?
Cefazolin is an antiviral medication.
Cefazolin is only used for skin infections.
Cefazolin is a cephalosporin, which can have cross-reactivity with
penicillin.
Cefazolin is unrelated to penicillin and is safe for all patients.
6. Describe the significance of prescribing azithromycin for both chlamydia and
gonococcal infections in a single dose.
Azithromycin requires multiple doses for effectiveness.
Azithromycin is effective against both infections, allowing for
convenient treatment.
Azithromycin is used primarily for respiratory infections.
Azithromycin is only effective for chlamydia, not gonococcal
infections.
7. What is the recommended timing for taking pantoprazole?
Immediately before troublesome meals only
At least 1 hour before a meal
Immediately after meals
, Before or after meals as needed
8. Describe how Sildenafil (Viagra) can lead to hypotension in patients.
Sildenafil (Viagra) has no effect on blood pressure.
Sildenafil (Viagra) can cause vasodilation, leading to a decrease in
blood pressure.
Sildenafil (Viagra) increases heart rate, causing hypotension.
Sildenafil (Viagra) causes fluid retention, leading to hypotension.
9. One of your patients is started on verapamil (Calan). Before administering the
dose you check
Heart rate
Temperature
Weight
Urine output
10. What should be monitored alongside treatment with furosemide?
electrolytes and acid base balance
potassium levels
blood pressure
electrolytes and renal function
11. This is an expected adverse effect of penicillins and cephalosporins:
Renal disease
Nausea and diarrhea
, Candida infection
12. A nurse is caring for a client prescribed ferrous sulfate for the treatment of
anemia. Which of the following instructions should be included in client
teaching about this medication?
Take the medication on an empty stomach to maximize absorption
Notify your provider if your stool becomes dark green
Decrease dietary fiber intake while taking this medication
Take prescribed antacids at the same time as this medication
13. What is the primary instruction regarding the administration of risedronate?
Take at bedtime
Take with food
Take on an empty stomach
Take with a full glass of water
14. What are two potential reproductive effects of anabolic steroid use in
males?
Enhanced muscle growth and endurance
Improved fertility and sperm motility
Increased testosterone levels and libido
Testicular atrophy and low sperm count
15. Which of the following contraindications or warnings is appropriate for
tetracyclines?
"Avoid use in children or pregnant or nursing women"
