NURS 663 - EXAM 1 2026|2027 QUESTIONS WITH VERIFIED ANSWERS
|LATEST UPDATE
Bupropion dosing - CORRECT ANSWER -The 12 hour give 100 mg daily to start then increase 100 mg daily
every three weeks to a max dose of 200 mg twice a day. The 24 hour start at 150 mg then increase 150
mg each day every week to a maximum of 450 mg per day
Bupropion mechanism of action - CORRECT ANSWER -Like SSRI/SNRI, inhibits dopamine reuptake, an alpha
three beta 4 nicotinic antagonist
Bupropion side effects advantages and other uses 7 - CORRECT ANSWER -No sexual dysfunction,
substance abuse especially nicotine, ADHD, increased energy, decreased appetite, good augmentation, low
induction of mania
Escitalopram adverse effects 2 - CORRECT ANSWER -QTc prolongation/SI
escitalopram dosing - CORRECT ANSWER -Initial dose is 10 mg per day increase at 10 mg a day per week
and the max dose is 30 mg a day
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,Fluoxetine mnemonic - CORRECT ANSWER -FLUoxetine remember that the flu lasts 1 to 2 weeks which is
related to the longer half-life of fluoxetine
Fluoxetine interactions - CORRECT ANSWER --Warfarin (flux can displace it)
-St. John's wort (may cause Serotonin Syndrome) burn up and can overdose
-Dabigatran
P450 interactions are significant
Sertraline mnemonic - CORRECT ANSWER -SQUIRTraline related to its adverse effects of increased
diarrhea and the benefit of a safe while pregnancy and breast-feeding
sertraline indication/benefits - CORRECT ANSWER -MDD, OCD, PMDD middle of the road antidepressant
with no buildup
Paroxetine adverse effects - CORRECT ANSWER -Withdrawal symptoms, more sedating, increase appetite
Paroxetine mnemonic - CORRECT ANSWER -Think pair of oxen related to it works fast and has a short half-
life
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, Paroxetine Interactions - CORRECT ANSWER -Potent CYP 2D6 Inhibitor and substrate equals many
interactions
Paroxetine dosing - CORRECT ANSWER -Immediate release start at 20 mg per day and titrate 10 to 20 mg
per day per week max dose is 50 mg per day, Extended release start at 25 mg per day increase by 12.5
mg per day each week to a max dose of 62.5 mg
Anti-depressants side effects 10 - CORRECT ANSWER -Anhedonia, apathy, n/v, drowsy/dizzy, somnolence,
headache, bruxism, vivid dreams, fatigue, change in sexual behavior.
Antidepressant Mechanism on action - CORRECT ANSWER -Ser-438 residue determines potency (hSERT)
SSRI (unk exact mech).
sertraline dose - CORRECT ANSWER -Init 20mg/day, titrate 25-50mg/day every 1-2wk, max dose 200mg
Fluoxetine indications - CORRECT ANSWER -Depression, d/c syndrome (give 20mg tab), for activation,
noncompliance, and to decrease appetite
Citalopram (Celexa) and Escitalopram (Lexapro) Pneumonic - CORRECT ANSWER -Think car seat for
SEATalopram to remember to obtain an Electrocardiogram forQTC prolongation
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|LATEST UPDATE
Bupropion dosing - CORRECT ANSWER -The 12 hour give 100 mg daily to start then increase 100 mg daily
every three weeks to a max dose of 200 mg twice a day. The 24 hour start at 150 mg then increase 150
mg each day every week to a maximum of 450 mg per day
Bupropion mechanism of action - CORRECT ANSWER -Like SSRI/SNRI, inhibits dopamine reuptake, an alpha
three beta 4 nicotinic antagonist
Bupropion side effects advantages and other uses 7 - CORRECT ANSWER -No sexual dysfunction,
substance abuse especially nicotine, ADHD, increased energy, decreased appetite, good augmentation, low
induction of mania
Escitalopram adverse effects 2 - CORRECT ANSWER -QTc prolongation/SI
escitalopram dosing - CORRECT ANSWER -Initial dose is 10 mg per day increase at 10 mg a day per week
and the max dose is 30 mg a day
1|Page
,Fluoxetine mnemonic - CORRECT ANSWER -FLUoxetine remember that the flu lasts 1 to 2 weeks which is
related to the longer half-life of fluoxetine
Fluoxetine interactions - CORRECT ANSWER --Warfarin (flux can displace it)
-St. John's wort (may cause Serotonin Syndrome) burn up and can overdose
-Dabigatran
P450 interactions are significant
Sertraline mnemonic - CORRECT ANSWER -SQUIRTraline related to its adverse effects of increased
diarrhea and the benefit of a safe while pregnancy and breast-feeding
sertraline indication/benefits - CORRECT ANSWER -MDD, OCD, PMDD middle of the road antidepressant
with no buildup
Paroxetine adverse effects - CORRECT ANSWER -Withdrawal symptoms, more sedating, increase appetite
Paroxetine mnemonic - CORRECT ANSWER -Think pair of oxen related to it works fast and has a short half-
life
2|Page
, Paroxetine Interactions - CORRECT ANSWER -Potent CYP 2D6 Inhibitor and substrate equals many
interactions
Paroxetine dosing - CORRECT ANSWER -Immediate release start at 20 mg per day and titrate 10 to 20 mg
per day per week max dose is 50 mg per day, Extended release start at 25 mg per day increase by 12.5
mg per day each week to a max dose of 62.5 mg
Anti-depressants side effects 10 - CORRECT ANSWER -Anhedonia, apathy, n/v, drowsy/dizzy, somnolence,
headache, bruxism, vivid dreams, fatigue, change in sexual behavior.
Antidepressant Mechanism on action - CORRECT ANSWER -Ser-438 residue determines potency (hSERT)
SSRI (unk exact mech).
sertraline dose - CORRECT ANSWER -Init 20mg/day, titrate 25-50mg/day every 1-2wk, max dose 200mg
Fluoxetine indications - CORRECT ANSWER -Depression, d/c syndrome (give 20mg tab), for activation,
noncompliance, and to decrease appetite
Citalopram (Celexa) and Escitalopram (Lexapro) Pneumonic - CORRECT ANSWER -Think car seat for
SEATalopram to remember to obtain an Electrocardiogram forQTC prolongation
3|Page
