Page 1 of 110
EVOLVE HESI PHARM EXAM | {LATEST 2026/
2027 UPDATE} COMPLETE ACTUAL AND
AUTHENTIC EXAM | BRAND NEW!
During therapy with isoniazid, it is most important for the nurse
to monitor which laboratory value closely?
A. Liver enzyme levels
B. Blood urea nitrogen (BUN) level
C. Serum electrolyte levels
D. Complete blood count (CBC)
A. Liver enzyme levels
The client receiving isoniazid is at risk for the development of
hepatitis; therefore, liver function test results should be
monitored carefully during drug therapy. Options B, C, and D , are
not specific indicators of liver function, so they are not monitored
closely during isoniazid therapy.
,Page 2 of 110
Alteration of which laboratory finding represents the
achievement of a therapeutic goal for heparin administration?
A. Prothrombin time (PT)
B. Fibrin split products
C. Platelet count
D. Partial thromboplastin time (PTT)
D. Partial thromboplastin time (PTT)
Heparin therapy is guided by changes in the partial
thromboplastin time (PTT). Options A, B, and C are not used to
track the therapeutic effect of heparin administration.
A client with mild parkinsonism is started on oral amantadine.
Which statement accurately describes the action of this
medication?
A. Viral organisms that provide the underlyling pathophysiology
for parkinsonism are eliminated.
B. Acetylcholine in the myoneural junction is enhanced.
C. Dopamine in the central nervous system is increased.
,Page 3 of 110
D. Norepinephrine release is reduced within the peripheral
system as the final step in dopamine uptake.
C. Dopamine in the central nervous system is increased.
Amantadine is a dopamine - releasing agent; therefore, this
medication increases the amount of dopamine present in the
central nervous system. Although this medication is also an
antiviral agent, the antiviral effect is not significant in the
treatment of pa rkinsonism. Options B and D are not affected by
amantadine.
A client is taking famotidine. Which client statement should the
nurse further assess because it may indicate that the client is
experiencing a side effect of this drug?
A. "I have heartburn whenever I lie down."
B. "I am never hungry. I've lost weight in the past 2 weeks."
C. "I have a funny metallic taste in my mouth."
D. "I seem to be having difficulty thinking clearly."
D. "I seem to be having difficulty thinking clearly."
, Page 4 of 110
A common side effect of of famotidine is confusion. Options A, B,
and C are not side effects of this medication.
A client with HIV who was recently diagnosed with tuberculosis
(TB) asks the nurse, "Why do I need to take all of these
medications for TB?" What information should the nurse provide?
A. Antiretroviral medications decrease the efficacy of the TB
drugs.
B. Multiple drugs prevent the development of resistant
organisms.
C. Duration of the medication regimen is shortened.
D. Potential adverse drug reactions are minimized.
B. Multiple drugs prevent the development of resistant
organisms.
A multidrug regimen is prescribed for a client with HIV and TB to
prevent the development of resistance of the tubercle bacilli.
Although antitubercular medications can inhibit some
antiretrovirals, a multidrug regimen is needed to inhibit the
proliferatio n of the virulent tubercle bacilli. The duration of
antitubercular therapy is typically 6 to 9 months and is not
EVOLVE HESI PHARM EXAM | {LATEST 2026/
2027 UPDATE} COMPLETE ACTUAL AND
AUTHENTIC EXAM | BRAND NEW!
During therapy with isoniazid, it is most important for the nurse
to monitor which laboratory value closely?
A. Liver enzyme levels
B. Blood urea nitrogen (BUN) level
C. Serum electrolyte levels
D. Complete blood count (CBC)
A. Liver enzyme levels
The client receiving isoniazid is at risk for the development of
hepatitis; therefore, liver function test results should be
monitored carefully during drug therapy. Options B, C, and D , are
not specific indicators of liver function, so they are not monitored
closely during isoniazid therapy.
,Page 2 of 110
Alteration of which laboratory finding represents the
achievement of a therapeutic goal for heparin administration?
A. Prothrombin time (PT)
B. Fibrin split products
C. Platelet count
D. Partial thromboplastin time (PTT)
D. Partial thromboplastin time (PTT)
Heparin therapy is guided by changes in the partial
thromboplastin time (PTT). Options A, B, and C are not used to
track the therapeutic effect of heparin administration.
A client with mild parkinsonism is started on oral amantadine.
Which statement accurately describes the action of this
medication?
A. Viral organisms that provide the underlyling pathophysiology
for parkinsonism are eliminated.
B. Acetylcholine in the myoneural junction is enhanced.
C. Dopamine in the central nervous system is increased.
,Page 3 of 110
D. Norepinephrine release is reduced within the peripheral
system as the final step in dopamine uptake.
C. Dopamine in the central nervous system is increased.
Amantadine is a dopamine - releasing agent; therefore, this
medication increases the amount of dopamine present in the
central nervous system. Although this medication is also an
antiviral agent, the antiviral effect is not significant in the
treatment of pa rkinsonism. Options B and D are not affected by
amantadine.
A client is taking famotidine. Which client statement should the
nurse further assess because it may indicate that the client is
experiencing a side effect of this drug?
A. "I have heartburn whenever I lie down."
B. "I am never hungry. I've lost weight in the past 2 weeks."
C. "I have a funny metallic taste in my mouth."
D. "I seem to be having difficulty thinking clearly."
D. "I seem to be having difficulty thinking clearly."
, Page 4 of 110
A common side effect of of famotidine is confusion. Options A, B,
and C are not side effects of this medication.
A client with HIV who was recently diagnosed with tuberculosis
(TB) asks the nurse, "Why do I need to take all of these
medications for TB?" What information should the nurse provide?
A. Antiretroviral medications decrease the efficacy of the TB
drugs.
B. Multiple drugs prevent the development of resistant
organisms.
C. Duration of the medication regimen is shortened.
D. Potential adverse drug reactions are minimized.
B. Multiple drugs prevent the development of resistant
organisms.
A multidrug regimen is prescribed for a client with HIV and TB to
prevent the development of resistance of the tubercle bacilli.
Although antitubercular medications can inhibit some
antiretrovirals, a multidrug regimen is needed to inhibit the
proliferatio n of the virulent tubercle bacilli. The duration of
antitubercular therapy is typically 6 to 9 months and is not
