NCLEX EXAM vc
Exam Solution
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UWorld NCLEX RN Pharmacology 2026 A+ GRADE ASSUvc vc vc vc vc vc vc
RED COMPLETE SOLUTIONS AND VERIFIED ANSWERS (
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B34C3)
QUESTION 1 vc
Naloxone
ANSWER
(narcan) opioid antagonist -counteracts the effects of opioids/ post-op anesthesia/ over-sedation -
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short halflife (wears off in 1-2h) -
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important to assess respiratory status at 1 h post administration and perform appropriate action(s)
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QUESTION 2 vc
Opioid analgesics: side effects
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ANSWER
sedation hypotension/ orthostatic hypotension N/V (short-term effect) constipation (long-
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term effect) respiratory depression
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QUESTION 3 vc
codeine is an vc vc
ANSWER
opioid
QUESTION 4 vc
______position will decrease nausea vc vc vc
ANSWER
still, supine (anti-emetic may be necessary initially)
vc vc vc vc vc vc
,QUESTION 5 vc
Opioid analgesics: nursing indications
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ANSWER
-monitor sedation level -instruct pt not to get out of bed unassisted -administer PRN stool softeners
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QUESTION 6 vc
It is most important for the nurse to monitor _______ when a pt is taking opioid analgesics;
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notify the HCP if the pt:
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A. _____________ or
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B. _____________
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ANSWER
sedation level vc
A. falls asleep during conversation
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B. has minimal or no response to verbal or physical stimuli
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QUESTION 7 vc
If the pt falls asleep during conversation:
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ANSWER
monitor respiratory status and notify HCP to decrease sedation by 25-
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50% (slightly drowsy is acceptable/normal)
vc vc vc vc
QUESTION 8 vc
If pt has minimal or no response to verbal/physical stimuli:
vc vc vc vc vc vc vc vc vc
ANSWER
stop sedation, consider using naloxone, notify HCP, monitor respiratory status
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QUESTION 9 vc
Pts at high risk for respiratory depression associated w/ opioid analgesics:
vc vc vc vc vc vc vc vc vc vc
ANSWER
-advanced age -surgery w/in 24 h -COPD/ underlying pulmonary disease -smoking -snoring -obesity -
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opiate naive vc
,QUESTION 10 vc
IV hydromorphone should be given _______, over ______-______ minutes
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ANSWER
slowly, 2-3 minutes vc vc
QUESTION 11 vc
Hold morphine if RR is less than
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ANSWER
12
QUESTION 12 vc
Pt prescribed IV PCA, but still has a lot of pain-
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ANSWER
preform thorough pain assessment
vc vc vc
QUESTION 13 vc
Extended release Oxycodone or Oxycontin, a long-
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acting opioid analgesic, is given when immediate release opioids are inadequate for pain
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management; they should be administered __________, even if the pt denies ________
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ANSWER
around-the-
clock pain (effective for 12 h; administered 2x daily) *tolerance and dependence is developed and highe
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r doses are eventually required to achieve therapeutic effect
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QUESTION 14 vc
NSAIDs
ANSWER
-naproxen (Aleve) -ibuprofen (Advil) -idomethacin (Tivorbex) -ketorlac (Toradol) *potent*
vc vc vc vc vc vc vc vc
QUESTION 15 vc
Complications associated with NSAIDs vc vc vc
ANSWER
, -GI toxicity: dyspepsia, peptic ulcers, pain, bleeding (report black tarry stool and take med w/ food) -
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Nephrotoxicity: (associated w/ long term use; can lead to AKI and CKD) -
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HTN and HF: NSAIDs can cause fluid retention which can exacerbate HF, HTN, and ascites, or lead to MI,
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or stroke -
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Bleeding: mainly GI (tell HCP if taking w/ other NSAIDs, aspirin, or anti platelets) *Do not give NSAIDs t
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o pts who have the above conditions* *NSAIDs should be used at the lowest dose for the shortest period
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possible*
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QUESTION 16 vc
NSAIDs decrease the effectiveness of _______ and ______ medications
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ANSWER
diuretic, blood pressure vc vc
QUESTION 17 vc
Misoprostol
ANSWER
tx: prevents gastric ulcers in long-
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term NSAID therapy; induces labor Indications: *can be taken w/ food but NOT ANTACIDs *effective birt
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h control should be in place *causes labor induction (can give to induce labor but NOT w/ oxytocin, pt
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w c-section hx, and pt w/ abnormal cxs)
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QUESTION 18 vc
Salicylate meds vc
ANSWER
acetylsalicylic acid (Aspirin) acetaminophen (Tylenol) bismuth subsalicylate (Pepto Bismol)
vc vc vc vc vc vc vc vc
QUESTION 19 vc
acetylsalicylic acid (Aspirin) overdose vc vc vc
ANSWER
Give activated charcoal
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QUESTION 20 vc
Aspirin and other salicylate meds should not be given to children with viral infections su
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ch as ______ or _______, otherwise _______syndrome can occur
vc vc vc vc vc vc vc vc
Exam Solution
vc
UWorld NCLEX RN Pharmacology 2026 A+ GRADE ASSUvc vc vc vc vc vc vc
RED COMPLETE SOLUTIONS AND VERIFIED ANSWERS (
vc vc vc vc vc vc
B34C3)
QUESTION 1 vc
Naloxone
ANSWER
(narcan) opioid antagonist -counteracts the effects of opioids/ post-op anesthesia/ over-sedation -
vc vc vc vc vc vc vc vc vc vc vc
short halflife (wears off in 1-2h) -
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important to assess respiratory status at 1 h post administration and perform appropriate action(s)
vc vc vc vc vc vc vc vc vc vc vc vc vc
QUESTION 2 vc
Opioid analgesics: side effects
vc vc vc
ANSWER
sedation hypotension/ orthostatic hypotension N/V (short-term effect) constipation (long-
vc vc vc vc vc vc vc vc
term effect) respiratory depression
vc vc vc
QUESTION 3 vc
codeine is an vc vc
ANSWER
opioid
QUESTION 4 vc
______position will decrease nausea vc vc vc
ANSWER
still, supine (anti-emetic may be necessary initially)
vc vc vc vc vc vc
,QUESTION 5 vc
Opioid analgesics: nursing indications
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ANSWER
-monitor sedation level -instruct pt not to get out of bed unassisted -administer PRN stool softeners
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
QUESTION 6 vc
It is most important for the nurse to monitor _______ when a pt is taking opioid analgesics;
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notify the HCP if the pt:
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A. _____________ or
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B. _____________
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ANSWER
sedation level vc
A. falls asleep during conversation
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B. has minimal or no response to verbal or physical stimuli
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QUESTION 7 vc
If the pt falls asleep during conversation:
vc vc vc vc vc vc
ANSWER
monitor respiratory status and notify HCP to decrease sedation by 25-
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50% (slightly drowsy is acceptable/normal)
vc vc vc vc
QUESTION 8 vc
If pt has minimal or no response to verbal/physical stimuli:
vc vc vc vc vc vc vc vc vc
ANSWER
stop sedation, consider using naloxone, notify HCP, monitor respiratory status
vc vc vc vc vc vc vc vc vc
QUESTION 9 vc
Pts at high risk for respiratory depression associated w/ opioid analgesics:
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ANSWER
-advanced age -surgery w/in 24 h -COPD/ underlying pulmonary disease -smoking -snoring -obesity -
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opiate naive vc
,QUESTION 10 vc
IV hydromorphone should be given _______, over ______-______ minutes
vc vc vc vc vc vc vc vc
ANSWER
slowly, 2-3 minutes vc vc
QUESTION 11 vc
Hold morphine if RR is less than
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ANSWER
12
QUESTION 12 vc
Pt prescribed IV PCA, but still has a lot of pain-
vc vc vc vc vc vc vc vc vc vc
ANSWER
preform thorough pain assessment
vc vc vc
QUESTION 13 vc
Extended release Oxycodone or Oxycontin, a long-
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acting opioid analgesic, is given when immediate release opioids are inadequate for pain
vc vc vc vc vc vc vc vc vc vc vc vc v
management; they should be administered __________, even if the pt denies ________
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ANSWER
around-the-
clock pain (effective for 12 h; administered 2x daily) *tolerance and dependence is developed and highe
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
r doses are eventually required to achieve therapeutic effect
vc vc vc vc vc vc vc vc
QUESTION 14 vc
NSAIDs
ANSWER
-naproxen (Aleve) -ibuprofen (Advil) -idomethacin (Tivorbex) -ketorlac (Toradol) *potent*
vc vc vc vc vc vc vc vc
QUESTION 15 vc
Complications associated with NSAIDs vc vc vc
ANSWER
, -GI toxicity: dyspepsia, peptic ulcers, pain, bleeding (report black tarry stool and take med w/ food) -
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
Nephrotoxicity: (associated w/ long term use; can lead to AKI and CKD) -
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HTN and HF: NSAIDs can cause fluid retention which can exacerbate HF, HTN, and ascites, or lead to MI,
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or stroke -
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Bleeding: mainly GI (tell HCP if taking w/ other NSAIDs, aspirin, or anti platelets) *Do not give NSAIDs t
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o pts who have the above conditions* *NSAIDs should be used at the lowest dose for the shortest period
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possible*
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QUESTION 16 vc
NSAIDs decrease the effectiveness of _______ and ______ medications
vc vc vc vc vc vc vc vc
ANSWER
diuretic, blood pressure vc vc
QUESTION 17 vc
Misoprostol
ANSWER
tx: prevents gastric ulcers in long-
vc vc vc vc vc
term NSAID therapy; induces labor Indications: *can be taken w/ food but NOT ANTACIDs *effective birt
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
h control should be in place *causes labor induction (can give to induce labor but NOT w/ oxytocin, pt
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w c-section hx, and pt w/ abnormal cxs)
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QUESTION 18 vc
Salicylate meds vc
ANSWER
acetylsalicylic acid (Aspirin) acetaminophen (Tylenol) bismuth subsalicylate (Pepto Bismol)
vc vc vc vc vc vc vc vc
QUESTION 19 vc
acetylsalicylic acid (Aspirin) overdose vc vc vc
ANSWER
Give activated charcoal
vc vc
QUESTION 20 vc
Aspirin and other salicylate meds should not be given to children with viral infections su
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
ch as ______ or _______, otherwise _______syndrome can occur
vc vc vc vc vc vc vc vc