INTRODUCTION CLINICAL
PHARMACOLOGY 9TH EDITION FULL
QUESTION SET 2026 ANSWERS AND
SOLUTIONS GRADED A+
⩥ Antihistamine.
Answer: Relieve the effects of histamine on body organs and structures
⩥ Antihistamines.
Answer: Limit the release of acetylcholine, producing an anticholinergic
(drying effect) In bronchioles and GI system
⩥ Antihistamines.
Answer: Have a sedative effect on the central nervous system
⩥ Histamine H2 antagonist.
Answer: Compete with histamine at H2 receptor sites, only H2 receptors
located in the GI tract
⩥ FDA.
,Answer: OTC cough and cold products not be used on infants and
children less than 2 years old, some should not be used in children
younger than 6
⩥ Second generation antihistamines.
Answer: Rapid onset of relief of sneezing, prutritus (itching), and watery
rhinorrhea...do not cross the blood brain barrier do not cause significant
sedation
⩥ Antihistamines
adverse reactions.
Answer: Constipation, blurred vision, dry mouth, urinary retention, and
dried thickened secretions caused by mucosal drying
⩥ Antihistamines.
Answer: Interacts with MAO inhibitors
Look for drug interactions
⩥ Antihistamines.
Answer: Should be used w/ caution in children w/ family history of
sleep apnea, SIDS, and Reye syndrome
⩥ Antihistamines
Implementation.
, Answer: Give oral doses with milk to lessen GI side effects
Given orally are usually well absorbed
⩥ Antihistamines
Implementation.
Answer: IM diphenhydramine inject deep to prevent tissue irritation
IV done slowly with patient laying down because of risk of low blood
pressure
⩥ Benadryl.
Answer: First generation
⩥ Loratadine Claritin.
Answer: 2nd generation
⩥ Antihistamines.
Answer: Start low go slow with older adults
⩥ Antihistamines.
Answer: Respiratory tract can dry out and mucus can thicken, encourage
fluids to thin secretions and moisten mucus membranes
PHARMACOLOGY 9TH EDITION FULL
QUESTION SET 2026 ANSWERS AND
SOLUTIONS GRADED A+
⩥ Antihistamine.
Answer: Relieve the effects of histamine on body organs and structures
⩥ Antihistamines.
Answer: Limit the release of acetylcholine, producing an anticholinergic
(drying effect) In bronchioles and GI system
⩥ Antihistamines.
Answer: Have a sedative effect on the central nervous system
⩥ Histamine H2 antagonist.
Answer: Compete with histamine at H2 receptor sites, only H2 receptors
located in the GI tract
⩥ FDA.
,Answer: OTC cough and cold products not be used on infants and
children less than 2 years old, some should not be used in children
younger than 6
⩥ Second generation antihistamines.
Answer: Rapid onset of relief of sneezing, prutritus (itching), and watery
rhinorrhea...do not cross the blood brain barrier do not cause significant
sedation
⩥ Antihistamines
adverse reactions.
Answer: Constipation, blurred vision, dry mouth, urinary retention, and
dried thickened secretions caused by mucosal drying
⩥ Antihistamines.
Answer: Interacts with MAO inhibitors
Look for drug interactions
⩥ Antihistamines.
Answer: Should be used w/ caution in children w/ family history of
sleep apnea, SIDS, and Reye syndrome
⩥ Antihistamines
Implementation.
, Answer: Give oral doses with milk to lessen GI side effects
Given orally are usually well absorbed
⩥ Antihistamines
Implementation.
Answer: IM diphenhydramine inject deep to prevent tissue irritation
IV done slowly with patient laying down because of risk of low blood
pressure
⩥ Benadryl.
Answer: First generation
⩥ Loratadine Claritin.
Answer: 2nd generation
⩥ Antihistamines.
Answer: Start low go slow with older adults
⩥ Antihistamines.
Answer: Respiratory tract can dry out and mucus can thicken, encourage
fluids to thin secretions and moisten mucus membranes
