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NURS231/ NURS 231 Exam 1: (Latest 2026/ 2027 Update) Pathophysiology: Cellular Adaptation, Injury, and Inflammation Review| Practice Questions with Verified Answers and Detailed Rationales| Grade A| 100% Correct (Verified Solutions) – Portage Learning

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INSTANT PDF DOWNLOAD — This comprehensive practice test for NURS 231 Exam 1 at Portage Learning covers Pathophysiology for the 2026/2027 academic year first examination. It features practice questions with verified answers and detailed rationales in multiple-choice, select-all-that-apply, true/false, and short answer formats aligned with the Portage Learning nursing curriculum. CELLULAR BIOLOGY FUNDAMENTALS (EXAM 1 FOCUS) Basic Cellular Structures and Functions Question 1: Cell Membrane Composition The cell membrane is primarily composed of: A) A single layer of phospholipids with embedded proteins B) A phospholipid bilayer with hydrophobic tails facing outward and hydrophilic heads facing inward C) A phospholipid bilayer with hydrophilic heads facing the aqueous environments and hydrophobic tails facing each other D) A protein bilayer with embedded phospholipids Correct Answer: C Rationale: The cell membrane (plasma membrane) consists of a phospholipid bilayer. The hydrophilic (water-loving) phosphate heads face outward toward the aqueous intracellular and extracellular environments. The hydrophobic (water-fearing) fatty acid tails face each other, away from water. This arrangement creates a semipermeable barrier. Embedded proteins serve functions such as transport, cell recognition, and enzymatic activity. The fluid mosaic model describes this dynamic structure. Question 2: Nucleus Function The primary function of the nucleus is to: A) Synthesize proteins B) Generate ATP through cellular respiration C) Store and protect the cell's genetic material (DNA) D) Package and modify proteins for secretion Correct Answer: C Rationale: The nucleus contains the cell's chromosomal DNA, which carries the genetic blueprint for protein synthesis and cellular regulation. It is enclosed by a double membrane (nuclear envelope) with nuclear pores that regulate transport between the nucleus and cytoplasm. The nucleolus within the nucleus is responsible for ribosome synthesis. Protein synthesis (A) occurs at ribosomes. ATP generation (B) occurs in mitochondria. Protein packaging/modification (D) occurs in the Golgi apparatus. Question 3: Mitochondria Which statement about mitochondria is accurate? A) Mitochondria are responsible for lipid synthesis and detoxification B) Mitochondria convert glucose into ATP through aerobic cellular respiration C) Mitochondria contain their own DNA that is inherited from both parents D) Mitochondria are the site of protein synthesis Correct Answer: B Rationale: Mitochondria are the "powerhouses" of the cell, generating ATP through aerobic cellular respiration (Krebs cycle and electron transport chain). The inner membrane forms cristae to increase surface area for ATP production. Mitochondria contain their own circular DNA (mtDNA), which is inherited maternally (from the mother). Cells with high energy demands (muscle, nerve, liver) contain more mitochondria. Statement C is incorrect because mtDNA is inherited from the mother only (maternal inheritance not both parents). Question 4: Ribosomes Ribosomes are responsible for: A) Lipid synthesis and detoxification of drugs B) Packaging of proteins into vesicles for secretion C) Protein synthesis (translation of mRNA) D) Breakdown of cellular waste and pathogens Correct Answer: C Rationale: Ribosomes are composed of rRNA and protein. They translate messenger RNA (mRNA) sequences into polypeptide chains, the process of protein synthesis. Ribosomes can be free in the cytoplasm (synthesizing proteins for intracellular use) or attached to the rough endoplasmic reticulum (synthesizing proteins for secretion or membrane incorporation). Lipid synthesis and detoxification (A) occur in smooth ER. Packaging (B) occurs in Golgi apparatus. Breakdown (D) occurs in lysosomes and proteasomes. Question 5: Endoplasmic Reticulum Rough endoplasmic reticulum (RER) is distinguished from smooth endoplasmic reticulum (SER) by the presence of: A) Golgi vesicles B) Ribosomes attached to its surface C) Cristae for increased surface area D) Enzymes for lipid synthesis Correct Answer: B Rationale: The rough ER is called "rough" because ribosomes are attached to its cytoplasmic surface. These ribosomes synthesize proteins that enter the RER lumen for folding, modification, and transport. The smooth ER lacks ribosomes and is involved in lipid synthesis, detoxification, carbohydrate metabolism, and calcium storage. Cristae are found in mitochondria (C).

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NURS 231 Pathophysiology 2026/2027 Exam 1

Questions | Verified Answers | Detailed Rationales |

Grade A | Portage Learning



1. Who was Florence Nightingale?
Correct Answer: Florence Nightingale was the founder of modern nursing,
also known as the "lady with the lamp." She advocated for patients to have
clean conditions and adequate nutrition, believed in giving patients
compassion, and was a nurse in the Crimean War where she and her team
saved many lives.
Rationale:
1. Florence Nightingale established the first secular nursing school.
2. She is a foundational figure in nursing history.
3. This is a standard nursing history question.


2. Who was Mary Breckinridge?
Correct Answer: Mary Breckinridge served communities that could not be
accessed by road or railway. She rode her horse to get to these underserved
communities. She believed in quality healthcare for everyone and that people
in rural areas deserved the same healthcare as those in the cities.
Rationale:
1. Mary Breckinridge founded the Frontier Nursing Service.

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2. She was a pioneer in rural healthcare and nurse-midwifery.
3. This is a standard nursing history question.


3. Who was Lillian Wald?
Correct Answer: Lillian Wald lobbied for women's rights and workplace
safety.
Rationale:
1. Lillian Wald founded the Henry Street Settlement and public health nursing.
2. This is a standard nursing history question.


4. Who was Mary Eliza Mahoney?
Correct Answer: Mary Eliza Mahoney was the first formally educated African
American nurse and a huge advocate for other African American nurses.
Rationale:
1. Mary Mahoney was a pioneer for diversity in nursing.
2. This is a standard nursing history question.


5. Who was Isabelle Hanson Robb?
Correct Answer: Isabelle Hanson Robb founded the American Nurses
Association (ANA) in 1911, which gave nurses a political voice and advocated
for nurses.
Rationale:
1. The ANA is the premier professional organization for nurses in the US.
2. This is a standard nursing history question.


6. Who was Kristen Swanson?

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Correct Answer: Kristen Swanson created the Theory of Caring and Healing.
Rationale:
1. Swanson's Theory of Caring is a middle-range nursing theory.
2. This is a standard nursing theory question.


7. What was the Theory of Caring and Healing?
Correct Answer: The Theory of Caring and Healing includes: maintaining
beliefs, knowing, being with, doing for, and enabling.
Rationale:
1. Swanson's theory defines five caring processes.
2. This is a standard nursing theory question.


8. What is "maintaining beliefs" according to Swanson's theory?
Correct Answer: Maintaining beliefs means ongoing faith, instilling hope,
appreciating the uniqueness of the individual, believing in the patient's ability
to reach goals, respecting the abilities of patients, offering realistic optimism,
and understanding the event considering physical, emotional, cultural, and
spiritual aspects.
Rationale:
1. This caring process focuses on the patient's faith and hope.
2. This is a standard nursing theory question.


9. What is "knowing" according to Swanson's theory?
Correct Answer: Knowing means acknowledging events in the patient's life
according to the meaning they hold for THEM, avoiding assumptions, showing

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Subido en
2 de mayo de 2026
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2025/2026
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