NUR 521 EXAM 4 BLUEPRINT PRACTICE QUESTIONS AND ANSWERS WITH RATIONALES 100% GUARANTEED PASS! (A+ GRADED) Section 1: Basic Questions About Antifungals Question 1 Which of the following is an opportunistic systemic fungal infection? • A) Sporotrichosis • B) Aspergillosis • C) Blastomycosis • D) Histoplasmosis Answer: B Rationale: Opportunistic systemic fungal infections occur in immunocompromised patients and include Aspergillosis, Candidiasis, Cryptococcosis, and Mucormycosis. Non-opportunistic infections, such as sporotrichosis, blastomycosis, and histoplasmosis, affect healthy individuals. Question 2 What is the drug of choice (DOC) for most systemic fungal infections? • A) Fluconazole • B) Amphotericin B • C) Itraconazole • D) Ketoconazole Answer: B Rationale: Amphotericin B is the DOC for most systemic fungal infections due to its broad-spectrum antifungal activity, despite its high toxicity. Question 3 Which antifungal is effective against both systemic and superficial fungal infections but has a black box warning for patients with heart failure? • A) Amphotericin B • B) Itraconazole • C) Fluconazole • D) Terbinafine Answer: B Rationale: Itraconazole is effective for both systemic and superficial fungal infections but has a BBW due to its negative inotropic effects, contraindicating its use in patients with heart failure. Question 4 Which antifungal is primarily used to treat superficial fungal infections, such as candidiasis? Continues...
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