Test Bank - Biochemistry, An Integrative Approach with Expanded Topics, 1st Edition (Tansey, 2020) Chapter 1-25 | All Chapters

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TEST BANK FOR
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Biochemistry, An Integrative Approach with
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Expanded Topics, 1st Edition (Tansey, 2020) Chapter
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1-25 | All Chapters
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,Table of Contents
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 Chapter 1: The Chemical Foundations of Biochemistry
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 Chapter 2: Nucleic Acids
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 Chapter 3: Proteins I: An Introduction to Protein Structure, Function and Purification
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 Chapter 4: Proteins II: Enzymes
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 Chapter 5: Membranes and an Introduction to Signal Transduction
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 Chapter 6: Carbohydrates I: Mono- and Disaccharides, Glycolysis, Gluconeogenesis, and the Fates of
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Pyruvate
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 Chapter 7: The Common Catabolic Pathway
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 Chapter 8: Carbohydrates II: Glycogen Metabolism, Pentose Phosphate Pathway, and Glycoconjugates
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 Chapter 9: Lipids I: Fatty Acids, Steroids, and Eicosanoids; Beta-Oxidation and Fatty Acid Biosynthesis
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 Chapter 10: Lipids II: Metabolism and Transport of Complex Lipids
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 Chapter 11: Amine Metabolism
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 Chapter 12: Metabolism Integration
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 Chapter 13: Nucleotide & Deoxynucleotide Metabolism
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 Chapter 14: DNA Replication, Damage and Repair
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 Chapter 15: RNA Synthesis And Processing
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 Chapter 16: Protein Synthesis
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 Chapter 17: Control Of Gene Expression
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 Chapter 18: Determination of Macromolecular Structure
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 Chapter 19: Allosterism and Receptor-Ligand Interactions
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 Chapter 20: Designer Proteins and Protein Folding
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 Chapter 21: Biomolecule Purification
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 Chapter 22: Bioinformatics and Omics
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 Chapter 23: Signal Transduction
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 Chapter 24: Protein Trafficking
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 Chapter 25: Photosynthesis & Nitrogen Fixation
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,Test Bank – Chapter 1 k k k k




The Chemical Foundations of Biochemistry
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Multiple Choice Questions (25 Questions) k k k k




1. Which of the following bonds is primarily responsible for the high specific heat capacity
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of water?
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a) Covalent bonds
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b) Ionic bonds
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c) Hydrogen bonds
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d) Van der Waals interactions
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e) Hydrophobic interactions
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Correct Answer: c k k




Explanation: Hydrogen bonds between water molecules require significant energy to
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break, giving water a high specific heat capacity. This allows water to resist temperature
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changes, which is critical for maintaining stable conditions in biological systems.
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2. A solution has a pH of 4.5. What is its hydrogen ion concentration [H¼]?
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a) 4.5 × 10½¶ M
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b) 3.16 × 10½· M
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c) 4.5 × 10½· M
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d) 3.16 × 10½¶ M
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e) 5.0 × 10½¶ M
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, Correct Answer: b k k




Explanation: pH = -log[H¼], so [H¼] = 10^(-pH) = 10^(-4.5) = 3.16 × 10½· M. This calculation
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is fundamental for understanding cellular pH environments.
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3. Which weak acid would be most effective as a buffer at pH 6.8?
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a) Acetic acid (pKa = 4.76)
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b) Carbonic acid (pKa₁ = 6.35)
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c) Phosphoric acid (pKa₁ = 2.14)
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d) Tris-HCl (pKa = 8.10)
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e) Lactic acid (pKa = 3.86)
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Correct Answer: b k k




Explanation: A buffer is most effective within ±1 pH unit of its pKa. Carbonic acid has pKa =
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6.35, which is closest to pH 6.8, making it the best choice for buffering at that pH.
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4. The hydrophobic effect is primarily driven by:
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a) Strong attraction between nonpolar molecules
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b) Covalent bonding between hydrocarbon chains
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c) Entropic increase of water molecules
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d) Ionic interactions between water and solutes
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e) Hydrogen bonding between nonpolar groups
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Correct Answer: c k k




Explanation: Nonpolar molecules disrupt the hydrogen-bonded network of water. Water
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molecules reorder around them, decreasing entropy. Clustering of hydrophobic
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molecules minimizes this ordered water, increasing entropy, which thermodynamically
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drives the hydrophobic effect.
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