Covered | Differential Diagnosis Psychiatric-Mental Health
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Foundations of Differential Diagnosis & Diagnostic Reasoning
(Weeks 1-2) (20 Questions)
Q1: A 34-year-old patient presents with depressed mood. According to hierarchical
diagnostic principles, which condition should be ruled out FIRST before considering
primary psychiatric disorders?
A. Major depressive disorder
B. Bipolar disorder
C. Substance-induced or medical condition causing depressive symptoms [CORRECT]
D. Persistent depressive disorder
Correct Answer: C
Rationale: The hierarchical approach requires ruling out substance-induced and general
medical conditions first, as these are often treatable and may fully explain symptoms.
Primary psychiatric diagnoses (Options A, B, D) are considered only after excluding
these etiologies. This follows DSM-5-TR Section I diagnostic guidelines.
Q2: Which component of the mental status exam assesses the patient's awareness of
their illness and need for treatment?
A. Thought content
B. Insight [CORRECT]
C. Judgment
D. Cognition
Correct Answer: B
,Rationale: Insight refers to the patient's awareness and understanding of their illness,
including recognition of symptoms as pathological and need for treatment. Judgment
(Option C) is the ability to make appropriate decisions. Thought content (Option A)
refers to what the patient is thinking about. Cognition (Option D) involves memory,
attention, and executive function.
Q3: A patient describes "racing thoughts" that move quickly between topics. Which
mental status exam component is being described?
A. Thought process [CORRECT]
B. Thought content
C. Mood
D. Affect
Correct Answer: A
Rationale: Thought process describes how a person thinks—the form and flow of ideas
(racing, flight of ideas, circumstantial, tangential, loose associations). Thought content
(Option B) is what they think about (delusions, obsessions). Mood (Option C) is
subjective emotional state. Affect (Option D) is observable emotional expression.
Q4: Which DSM-5-TR tool is designed to assess cultural factors affecting diagnosis and
treatment?
A. WHODAS 2.0
B. Cultural Formulation Interview (CFI) [CORRECT]
C. Global Assessment of Functioning (GAF)
D. Mini-Mental State Examination (MMSE)
Correct Answer: B
Rationale: The Cultural Formulation Interview (CFI) in DSM-5-TR Section III assesses
cultural identity, cultural explanations of illness, cultural factors related to stress and
coping, and cultural features of clinician-patient relationship. WHODAS 2.0 (Option A)
assesses disability. GAF (Option C) was removed from DSM-5. MMSE (Option D)
screens for cognitive impairment.
Q5: A patient reports "ataque de nervios" with symptoms of trembling, crying, and
dissociation following a stressful event. This is best understood as:
A. Panic disorder
,B. A cultural concept of distress [CORRECT]
C. Conversion disorder
D. Generalized anxiety disorder
Correct Answer: B
Rationale: "Ataque de nervios" is a recognized cultural concept of distress in DSM-5-TR,
common in Latino cultures, characterized by intense emotional upset, somatic
symptoms, and dissociation. While it may overlap with anxiety disorders, understanding
it as a cultural syndrome prevents misdiagnosis. It is not simply panic disorder (Option
A) or GAD (Option D), though comorbidity may exist.
Q6: Which term describes assessment focused on understanding the unique individual
rather than comparing to group norms?
A. Nomothetic assessment
B. Idiographic assessment [CORRECT]
C. Standardized assessment
D. Actuarial assessment
Correct Answer: B
Rationale: Idiographic assessment focuses on the individual's unique characteristics,
experiences, and context. Nomothetic assessment (Option A) compares individuals to
group norms and statistical patterns. Both approaches are valuable in differential
diagnosis—nomothetic for diagnostic criteria, idiographic for understanding the person's
specific presentation.
Q7: A patient has PHQ-9 score of 15. Which severity category does this indicate?
A. Minimal depression (0-4)
B. Mild depression (5-9)
C. Moderately severe depression (15-19) [CORRECT]
D. Severe depression (20-27)
Correct Answer: C
Rationale: PHQ-9 scoring: 0-4 minimal, 5-9 mild, 10-14 moderate, 15-19 moderately
severe, 20-27 severe. Score of 15 falls in moderately severe range, often warranting
active treatment and possible medication. This guides treatment intensity and
monitoring.
, Q8: Which reliability concept refers to consistency of diagnostic criteria across different
clinicians?
A. Test-retest reliability
B. Inter-rater reliability [CORRECT]
C. Internal consistency
D. Split-half reliability
Correct Answer: B
Rationale: Inter-rater reliability measures agreement between different clinicians using
the same diagnostic criteria—essential for valid differential diagnosis. Test-retest
(Option A) is consistency over time. Internal consistency (Option C) and split-half
(Option D) measure whether scale items measure the same construct.
Q9: A patient presents with anxiety symptoms that began immediately after starting
prednisone for asthma. Which diagnostic consideration is primary?
A. Generalized anxiety disorder
B. Panic disorder
C. Medication-induced anxiety disorder [CORRECT]
D. Social anxiety disorder
Correct Answer: C
Rationale: Corticosteroids like prednisone commonly cause anxiety, irritability, and
mood changes. The temporal relationship (symptoms beginning after medication start)
suggests medication-induced anxiety disorder. DSM-5-TR requires symptoms to be
clinically significant and not better explained by another condition. Other anxiety
disorders (Options A, B, D) would not have this clear temporal link to medication
initiation.
Q10: Which open-ended question technique helps clarify vague patient statements?
A. "Is your mood depressed?"
B. "Tell me more about what you mean when you say you feel 'off'" [CORRECT]
C. "Do you have thoughts of suicide?"
D. "Are you sleeping well?"
Correct Answer: B
Rationale: Clarification seeks to understand vague or ambiguous statements by asking
the patient to elaborate. "Tell me more" or "What do you mean by..." are clarifying