LAT LABORATORY ANIMAL TECHNICIAN
QUESTIONS AND ANSWERS FOR GUARANTEED
EXAM SUCCESS
U.S. Government provides approximately how much in research/development funds
spent by college and university?
2/3
What information is important on grant applications to request funds?
Detailed description of research goals, scientific basis of study, and review of relevant
literature and all procedures to be performed
What is the difference between NIH & NSF?
NIH: primary granting agency: academia, federal agencies, biomedical research
NSF: Basic research in math, medicine, and biology
The USDA stands for what?
United States Department of Agriculture
The USDA is responsible for what?
Enforces and amends AWA
,Auction, sale, exhibit, transport, breeding, or conduct of research with animals
Animals exempt from AWA
Research institutions must register with
Supply annual reports
Inspection records through the FOIA
Unscheduled inspection once per year
What does the FOIA stand for?
Freedom of Information Act - provides the USDA's inspection records
What is the Public Health Service Policy?
Institutions which receive funding from PHS and NIH must follow these guidelines,
requires filing of an Amimal Welfare Assurance document that demonstrates the
institution is following the Guid, PHS policy, AWA, and any other applicable laws
The FDA has many responsibilities including:
Assures that new drugs and medical devices are safe and effective before approved for
use in humans
Monitors drug approval
Includes human, and veterinary drugs, food, and medical devices
Requires that effectiveness be demonstrated through well controlled investigations
What is GLP?
Good Laboratory Practices
,Established in 1978 with implementation of laboratory audits and inspection programs
Details requirements for QA and SOPs
What is the importance of importation and transportations regulations?
For the protection of humans and environment from potential disease carrying
organisms
Which agencies control importation?
CDC, USDA, and US Fish & Wildlife Service
Institutional polices are established for:
facility operations
care and use procedures
veterinary support
physical plant
Standard operating procedures relate to:
wall aspects of animal care and support
personnel management
health surveillance of animals and personnel
equipment
investigators
, What are the functions of IACUCs and who mandates?
mandated by AWA, PHS policy, and the Guide
Review and approve protocols for animal use
Review animal use program and perform animal facilities inspections at least every 6
months
What has to happen before animal research can begin?
principal investigator provides written details of how animals will be used in the research
project
IACUC must review all protocols using animals and must approve all protocols before
any animal research can begin
What does the IACUC determine?
Can deny permission or start a project
can stop a research project
Ensures compliance with regulations
Reviews complete protocols at least every 3 years; reviews updates to protocols yearly
What is the AAALAC, International?
Association for Assessment and Accreditation of Laboratory Animal Care, International
Non-profit organization that provides a mechanism for peer review of animal care and
use programs by scientific community
Detailed application with information on facilities, procedures, programs, and research
animals to use
Annual report must be submitted to AAALAC on status of animal care program
QUESTIONS AND ANSWERS FOR GUARANTEED
EXAM SUCCESS
U.S. Government provides approximately how much in research/development funds
spent by college and university?
2/3
What information is important on grant applications to request funds?
Detailed description of research goals, scientific basis of study, and review of relevant
literature and all procedures to be performed
What is the difference between NIH & NSF?
NIH: primary granting agency: academia, federal agencies, biomedical research
NSF: Basic research in math, medicine, and biology
The USDA stands for what?
United States Department of Agriculture
The USDA is responsible for what?
Enforces and amends AWA
,Auction, sale, exhibit, transport, breeding, or conduct of research with animals
Animals exempt from AWA
Research institutions must register with
Supply annual reports
Inspection records through the FOIA
Unscheduled inspection once per year
What does the FOIA stand for?
Freedom of Information Act - provides the USDA's inspection records
What is the Public Health Service Policy?
Institutions which receive funding from PHS and NIH must follow these guidelines,
requires filing of an Amimal Welfare Assurance document that demonstrates the
institution is following the Guid, PHS policy, AWA, and any other applicable laws
The FDA has many responsibilities including:
Assures that new drugs and medical devices are safe and effective before approved for
use in humans
Monitors drug approval
Includes human, and veterinary drugs, food, and medical devices
Requires that effectiveness be demonstrated through well controlled investigations
What is GLP?
Good Laboratory Practices
,Established in 1978 with implementation of laboratory audits and inspection programs
Details requirements for QA and SOPs
What is the importance of importation and transportations regulations?
For the protection of humans and environment from potential disease carrying
organisms
Which agencies control importation?
CDC, USDA, and US Fish & Wildlife Service
Institutional polices are established for:
facility operations
care and use procedures
veterinary support
physical plant
Standard operating procedures relate to:
wall aspects of animal care and support
personnel management
health surveillance of animals and personnel
equipment
investigators
, What are the functions of IACUCs and who mandates?
mandated by AWA, PHS policy, and the Guide
Review and approve protocols for animal use
Review animal use program and perform animal facilities inspections at least every 6
months
What has to happen before animal research can begin?
principal investigator provides written details of how animals will be used in the research
project
IACUC must review all protocols using animals and must approve all protocols before
any animal research can begin
What does the IACUC determine?
Can deny permission or start a project
can stop a research project
Ensures compliance with regulations
Reviews complete protocols at least every 3 years; reviews updates to protocols yearly
What is the AAALAC, International?
Association for Assessment and Accreditation of Laboratory Animal Care, International
Non-profit organization that provides a mechanism for peer review of animal care and
use programs by scientific community
Detailed application with information on facilities, procedures, programs, and research
animals to use
Annual report must be submitted to AAALAC on status of animal care program
