NUR3196 Final Exam Drugs (in Q
form) Study Guide
what is Isoniazid's therapeutic class? - ANSWER antituberculosis drug
what is Isoniazid's pharm class? - ANSWER mycolic acid inhibitor
Isoniazid is ___________ for actively growing organisms but _______________ for
dormant mycobacteria - ANSWER bactericidal, bacteriostatic
What statements made by the nurse indicate that they know the administration
alerts for isoniazid? - ANSWER "I should take this on an empty stomach"
"I should take INH an hour after or 2 hours before meals"
"If I am injecting IM, I should rotate sites"
SATA for common adverse effects of Isoniazid - ANSWER numbness of hands
and feet
rash
fever
The patient who took Isoniazid is experiencing parestheisa of the feet and
hands, convulsions, optic neuritis, dizziness, coma, memory loss, and various
psychoses. What is the term for what the patient is experiencing? - ANSWER
Neurotoxicity
what is the black box warning for the administration of INH? - ANSWER
hepatoxicity
what symptoms indicate hepatoxicity? - ANSWER jaundice, fatigue, elevated
hepatic enzymes, loss of appetite
what kind of pts should nurses be cautious of when giving INH to? - ANSWER
hypersensitivity to the drug
pts with severe hepatic impairment
what foods should you avoid when taking INH? - ANSWER foods containing
tyramine (cheese and meats, pickled foods, fermented sauces)
what can be infused in an equal dose of INH overdose to prevent seizures and to
correct metabolic acidosis? - ANSWER Pyridoxine (vitamin B6)
, what is Amphotericin B's therapeutic class? - ANSWER systemic antifungal
what is Amphotericin B's pharm class? - ANSWER polyene
What is a polyene? - ANSWER for prophylactic antifungal therapy
binds to ergosterol in fungal cell membranes, causing them to become
permeable or leaky
what can you do to reduce the nephrotoxicity and less infusion-related fever and
chills of Amphotericin B? - ANSWER formulate with lipids
the nurse shows her understanding of the admin alerts for amphotericin B by
these statements - ANSWER "I will infuse slowly b/c cardiovascular collapse may
result if the medication is infused too rapidly"
"I will premedicate acetaminophen, antihistamines, and corticosteroids to
decrease the risk of hypersensitivy reactions"
"I will withhold the drug is the BUN exceeds 40 mg/dL and if the serum creatinine
exceeds 3 mg/dL"
What adverse effects can develop at the beginning of Amph B therapy but
subside as treatment continues? - ANSWER fever and chills, vomiting, headache
what adverse effect is common during IV therapy for Amph B? - ANSWER
phlebitis
what are some serious adverse effects for Amph B and how can they be
monitored? - ANSWER nephrotoxicity-hypokalemia, cardiac arrest, hypotension,
and dysrhythmias
ototoxicity-hearing loss, vertigo, unsteady gait, tinnitus
what are Amph B's contraindications? - ANSWER pts with CKD, hypersensitivity
what drugs reduce kidney function? - ANSWER aminoglycosides, vancomycin,
or carboplatin
what drugs potentiate hypokalemia? - ANSWER corticosteroids, skeletal muscle
relaxants, and thiazole
what can overdose for Amph B result in and how should it be treated? - ANSWER
cardiorespiratory arrest
symptomatically
what is Fluconazole (Diflucan)'s therapeutic class? - ANSWER antifungal
what is Fluconazole (Diflucan)'s pharm class? - ANSWER azole, inhibitor of
fungal cell membrane synthesis
form) Study Guide
what is Isoniazid's therapeutic class? - ANSWER antituberculosis drug
what is Isoniazid's pharm class? - ANSWER mycolic acid inhibitor
Isoniazid is ___________ for actively growing organisms but _______________ for
dormant mycobacteria - ANSWER bactericidal, bacteriostatic
What statements made by the nurse indicate that they know the administration
alerts for isoniazid? - ANSWER "I should take this on an empty stomach"
"I should take INH an hour after or 2 hours before meals"
"If I am injecting IM, I should rotate sites"
SATA for common adverse effects of Isoniazid - ANSWER numbness of hands
and feet
rash
fever
The patient who took Isoniazid is experiencing parestheisa of the feet and
hands, convulsions, optic neuritis, dizziness, coma, memory loss, and various
psychoses. What is the term for what the patient is experiencing? - ANSWER
Neurotoxicity
what is the black box warning for the administration of INH? - ANSWER
hepatoxicity
what symptoms indicate hepatoxicity? - ANSWER jaundice, fatigue, elevated
hepatic enzymes, loss of appetite
what kind of pts should nurses be cautious of when giving INH to? - ANSWER
hypersensitivity to the drug
pts with severe hepatic impairment
what foods should you avoid when taking INH? - ANSWER foods containing
tyramine (cheese and meats, pickled foods, fermented sauces)
what can be infused in an equal dose of INH overdose to prevent seizures and to
correct metabolic acidosis? - ANSWER Pyridoxine (vitamin B6)
, what is Amphotericin B's therapeutic class? - ANSWER systemic antifungal
what is Amphotericin B's pharm class? - ANSWER polyene
What is a polyene? - ANSWER for prophylactic antifungal therapy
binds to ergosterol in fungal cell membranes, causing them to become
permeable or leaky
what can you do to reduce the nephrotoxicity and less infusion-related fever and
chills of Amphotericin B? - ANSWER formulate with lipids
the nurse shows her understanding of the admin alerts for amphotericin B by
these statements - ANSWER "I will infuse slowly b/c cardiovascular collapse may
result if the medication is infused too rapidly"
"I will premedicate acetaminophen, antihistamines, and corticosteroids to
decrease the risk of hypersensitivy reactions"
"I will withhold the drug is the BUN exceeds 40 mg/dL and if the serum creatinine
exceeds 3 mg/dL"
What adverse effects can develop at the beginning of Amph B therapy but
subside as treatment continues? - ANSWER fever and chills, vomiting, headache
what adverse effect is common during IV therapy for Amph B? - ANSWER
phlebitis
what are some serious adverse effects for Amph B and how can they be
monitored? - ANSWER nephrotoxicity-hypokalemia, cardiac arrest, hypotension,
and dysrhythmias
ototoxicity-hearing loss, vertigo, unsteady gait, tinnitus
what are Amph B's contraindications? - ANSWER pts with CKD, hypersensitivity
what drugs reduce kidney function? - ANSWER aminoglycosides, vancomycin,
or carboplatin
what drugs potentiate hypokalemia? - ANSWER corticosteroids, skeletal muscle
relaxants, and thiazole
what can overdose for Amph B result in and how should it be treated? - ANSWER
cardiorespiratory arrest
symptomatically
what is Fluconazole (Diflucan)'s therapeutic class? - ANSWER antifungal
what is Fluconazole (Diflucan)'s pharm class? - ANSWER azole, inhibitor of
fungal cell membrane synthesis
