Chapter 2 Test Bank Questions
Study online at https://quizlet.com/_j93qlu
1. 1. A patient's nutritional intake and laboratory results 1. Distribution of drugs to
reflect hypoalbuminemia. This is critical to prescribing target tissue may be af-
because: fected.
1. Distribution of drugs to target tissue may be affect-
ed.
2. The solubility of the drug will not match the site of
absorption.
3. There will be less free drug available to generate an
effect.
4. Drugs bound to albumin are readily excreted by the
kidneys.
2. 2. Drugs that have a significant first-pass effect: 3. Are rapidly metabolized
1. Must be given by the enteral (oral) route only by the liver and may have
2. Bypass the hepatic circulation little if any desired action
3. Are rapidly metabolized by the liver and may have
little if any desired action
4. Are converted by the liver to more active and fat-sol-
uble forms
3. 3. The route of excretion of a volatile drug will likely be 2. Lungs
the:
1. Kidneys
2. Lungs
3. Bile and feces
4. Skin
4. 4. Medroxyprogesterone (Depo Provera) is prescribed 3. Increase the length of
intramuscularly (IM) to create a storage reservoir of time a drug is available
the drug. Storage reservoirs: and active
1. Assure that the drug will reach its intended target
tissue
1/9
, Chapter 2 Test Bank Questions
Study online at https://quizlet.com/_j93qlu
2. Are the reason for giving loading doses
3. Increase the length of time a drug is available and
active
4. Are most common in collagen tissues
5. 5. The NP chooses to give cephalexin every 8 hours 2. Biological half-life
based on knowledge of the drug's:
1. Propensity to go to the target receptor
2. Biological half-life
3. Pharmacodynamics
4. Safety and side effects
6. 6. Azithromycin dosing requires that the first day's 1. Rapidly achieves drug
dosage be twice those of the other 4 days of the pre- levels in the therapeutic
scription. This is considered a loading dose. A loading range
dose:
1. Rapidly achieves drug levels in the therapeutic
range
2. Requires four- to five-half-lives to attain
3. Is influenced by renal function
4. Is directly related to the drug circulating to the target
tissues
7. The point in time on the drug concentration curve that 3. Onset of action
indicates the first sign of a therapeutic effect is the:
1. Minimum adverse effect level
2. Peak of action
3. Onset of action
4. Therapeutic range
8. 8. Phenytoin requires that a trough level be drawn. 4. To determine if a drug is
Peak and trough levels are done: in the therapeutic range
1. When the drug has a wide therapeutic range
2/9
Study online at https://quizlet.com/_j93qlu
1. 1. A patient's nutritional intake and laboratory results 1. Distribution of drugs to
reflect hypoalbuminemia. This is critical to prescribing target tissue may be af-
because: fected.
1. Distribution of drugs to target tissue may be affect-
ed.
2. The solubility of the drug will not match the site of
absorption.
3. There will be less free drug available to generate an
effect.
4. Drugs bound to albumin are readily excreted by the
kidneys.
2. 2. Drugs that have a significant first-pass effect: 3. Are rapidly metabolized
1. Must be given by the enteral (oral) route only by the liver and may have
2. Bypass the hepatic circulation little if any desired action
3. Are rapidly metabolized by the liver and may have
little if any desired action
4. Are converted by the liver to more active and fat-sol-
uble forms
3. 3. The route of excretion of a volatile drug will likely be 2. Lungs
the:
1. Kidneys
2. Lungs
3. Bile and feces
4. Skin
4. 4. Medroxyprogesterone (Depo Provera) is prescribed 3. Increase the length of
intramuscularly (IM) to create a storage reservoir of time a drug is available
the drug. Storage reservoirs: and active
1. Assure that the drug will reach its intended target
tissue
1/9
, Chapter 2 Test Bank Questions
Study online at https://quizlet.com/_j93qlu
2. Are the reason for giving loading doses
3. Increase the length of time a drug is available and
active
4. Are most common in collagen tissues
5. 5. The NP chooses to give cephalexin every 8 hours 2. Biological half-life
based on knowledge of the drug's:
1. Propensity to go to the target receptor
2. Biological half-life
3. Pharmacodynamics
4. Safety and side effects
6. 6. Azithromycin dosing requires that the first day's 1. Rapidly achieves drug
dosage be twice those of the other 4 days of the pre- levels in the therapeutic
scription. This is considered a loading dose. A loading range
dose:
1. Rapidly achieves drug levels in the therapeutic
range
2. Requires four- to five-half-lives to attain
3. Is influenced by renal function
4. Is directly related to the drug circulating to the target
tissues
7. The point in time on the drug concentration curve that 3. Onset of action
indicates the first sign of a therapeutic effect is the:
1. Minimum adverse effect level
2. Peak of action
3. Onset of action
4. Therapeutic range
8. 8. Phenytoin requires that a trough level be drawn. 4. To determine if a drug is
Peak and trough levels are done: in the therapeutic range
1. When the drug has a wide therapeutic range
2/9
