NR293 EXAM 2 2026 ACTUAL SCRIPT FULL
SOLUTION STUDY MATERIAL
◉ Silver Sulfadiazine (Silvadene) Answer: Topical antiinfective
Treat/prevent infection at site of second or third degree burns
Adverse effects: pain, burning, itching
◉ Benzoyl Peroxide Answer: Causes death of the anaerobic P. acnes
bacteria by slowly releasing oxygen
Antibacterial, antiseptic, drying, and keratolytic actions
May cause skin peeling, redness, or warmth
Improvement in 4-6 weeks
◉ Clindamycin (Cleocin T) Answer: Antibiotic used topically to treat
acne
,Adverse effects - minor skin reactions, burning, itching, dryness,
oiliness, and peeling
◉ Isotrentinoin (Amnesteem, Claravis, Sotret) Answer: Treatment of
severe resistant cystic acne
- Inhibits sebaceous gland activity and has antikeratinizing and
antiinflammatory effects
Company producing Accutane withdrew it from market
◉ Isotretinoin Answer: Treats acne
Stringent guidelines for prescribing and use
iPLEDGE program for safety
Monitor for signs of depression or suicidal thoughts
◉ Tretinoin (Retinoic acid, Vitamin A acid) (Renova, Retin-A)
Answer: Treats acne
Reduce dermatologic changes with sun damage
,Stimulates turnover of epithelial cells = skin peeling
◉ What drugs affect the eye? Answer: Mydriatics (Apraclonidine) -
dilate pupil
Miotics (acetylcholine, pilocarpine) - constrict pupil
Cycloplegics (atropine, cyclopentolate) - paralyze ciliary body
◉ Glaucoma Answer: Inhibition of the normal flow and drainage of
aqueous humor
- Results in increased intraocular pressure (IOP)
Pressure against retina destroys neurons, leading to impaired vision
and blindness
◉ What are the types of glaucomas? Answer: Angle-closure
glaucoma
Open-angle glaucoma
, Can be primary, secondary, or congenital depending on underlying
cause
◉ Cholinergic Drugs Answer: Mimic the parasympathetic nervous
system neurotransmitter acetylcholine
Cause pupillary constriction (miosis) which leads to reduced IOP
◉ What are the direct-acting cholinergic drugs? Answer:
Acetylcholine (Miochol-E)
Carbachol (Carboptic)
Pilocarpine (Pilocar)
◉ What is the indirect-acting cholinergic drug? Answer:
Echothiophate (Phospholine Iodide)
◉ Sympathomimetics Answer: Mimic the sympathetic
neurotransmitters epinephrine and norepinephrine
Stimulate the dilator muscle to contract = increased pupil size
(mydriasis)
SOLUTION STUDY MATERIAL
◉ Silver Sulfadiazine (Silvadene) Answer: Topical antiinfective
Treat/prevent infection at site of second or third degree burns
Adverse effects: pain, burning, itching
◉ Benzoyl Peroxide Answer: Causes death of the anaerobic P. acnes
bacteria by slowly releasing oxygen
Antibacterial, antiseptic, drying, and keratolytic actions
May cause skin peeling, redness, or warmth
Improvement in 4-6 weeks
◉ Clindamycin (Cleocin T) Answer: Antibiotic used topically to treat
acne
,Adverse effects - minor skin reactions, burning, itching, dryness,
oiliness, and peeling
◉ Isotrentinoin (Amnesteem, Claravis, Sotret) Answer: Treatment of
severe resistant cystic acne
- Inhibits sebaceous gland activity and has antikeratinizing and
antiinflammatory effects
Company producing Accutane withdrew it from market
◉ Isotretinoin Answer: Treats acne
Stringent guidelines for prescribing and use
iPLEDGE program for safety
Monitor for signs of depression or suicidal thoughts
◉ Tretinoin (Retinoic acid, Vitamin A acid) (Renova, Retin-A)
Answer: Treats acne
Reduce dermatologic changes with sun damage
,Stimulates turnover of epithelial cells = skin peeling
◉ What drugs affect the eye? Answer: Mydriatics (Apraclonidine) -
dilate pupil
Miotics (acetylcholine, pilocarpine) - constrict pupil
Cycloplegics (atropine, cyclopentolate) - paralyze ciliary body
◉ Glaucoma Answer: Inhibition of the normal flow and drainage of
aqueous humor
- Results in increased intraocular pressure (IOP)
Pressure against retina destroys neurons, leading to impaired vision
and blindness
◉ What are the types of glaucomas? Answer: Angle-closure
glaucoma
Open-angle glaucoma
, Can be primary, secondary, or congenital depending on underlying
cause
◉ Cholinergic Drugs Answer: Mimic the parasympathetic nervous
system neurotransmitter acetylcholine
Cause pupillary constriction (miosis) which leads to reduced IOP
◉ What are the direct-acting cholinergic drugs? Answer:
Acetylcholine (Miochol-E)
Carbachol (Carboptic)
Pilocarpine (Pilocar)
◉ What is the indirect-acting cholinergic drug? Answer:
Echothiophate (Phospholine Iodide)
◉ Sympathomimetics Answer: Mimic the sympathetic
neurotransmitters epinephrine and norepinephrine
Stimulate the dilator muscle to contract = increased pupil size
(mydriasis)
