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,3. The nurseis teaching a patient who will bedischarged home witha prescription for anenteric-
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x% coated tablet. Which statement by the patient
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a. Imay crush the tablet and put it inapplesauce to improve absorption.
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b. I should consume acidic foodsto enhance absorption of this medication.
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c. I should expect a delay in onset of the drugs effects after taking the tablet.
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d. I should take thismedication withhigh-
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x% fat foodsto improveits action. ANS: C
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% Enteric-
coated tablets resist disintegration in the acidic environment of the stomach and disintegrate whe
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n they reach the small intestine. There is usually some delay in onset of actions after taking these
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med ications. Enteric- x% x%




coated tablets should not be crushed or chewed, which would alter thetime and locationof absorpt
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i on. Acidic foods will not enhance the absorption of the medication. The patient should not to ea
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t hi gh-fat food before ingesting an enteric-coated tablet, because high-
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fat foods decrease the absorption rate.
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DIF:COGNITIVE LEVEL: Applying (Application) REF: dm 3 TOP x% x% x% x% x% x% x%




: NURSING PROCESS: Nursing Intervention
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MSC:NCLEX:Physiological Integrity:Pharmacological and Parenteral Therapies vj x% vj vj




4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must be giv
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e nbysubcutaneous injection instead of bymouth. Thenursewillexplain that this isbecause
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a. absorption is diminished bythe first-pass effects in the liver.
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b. absorption is faster when insulin is given subcutaneously. vj x% x% vj x% x% x%




c. digestiveenzymes in the gastrointestinaltract prevent absorption. x% x% x% x% x%




d. theoralformis less predictablewith more adverse effects. A x% x% x% x% vj x%




x% NS: C x%




Insulin, growth hormones, and other protein-
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based drugs are destroyed in the small intestine by digestive enzymes and must be given parenterall
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y. Because insulin is destroyed by digestive enzymes, it would not make it to the liver for metabolis
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m witha first-
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pass effect.Subcutaneous tissue has fewer blood vessels, so absorption is slower in such tissue. Ins
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x% ulin is given subcutaneously because it is desirable to have it absorb slowly.
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DIF:COGNITIVELEVEL:Understanding (Comprehension) REF: dm 3 TOP: x% x% x% x% x% x%




NURSING PROCESS: Nursing Intervention: Patient Teaching x% x% x% x% x%




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, MSC:NCLEX:Physiological Integrity:Pharmacological and Parenteral Therapies
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Page 3 of 507
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