PATgh201
1. Pharmacology:ghStudyghofghmedicines;ghhowghdrugsghimproveghorghmaintainghhealth
2. Therapeutics:g h Branchghofghmedicineghconcernedghwithghpreventionghofghdiseaseghandghtreatmentghofghsuttering.
3. Pharmacotherapeutics:ghAdministrationghofghdrugsghforgheitherghdiseaseghpreventionghorghtreatmentghandghreliefghof
suttering.
4. Drug:ghAghchemicalghagentghcapableghofghproducingghbiologicalghresponsesghwithinghtheghbody.
5. Therapeuticghvs.ghadverse:ghDesirableghvs.ghundesirable
6. Medication:g h Drugghthatghisghconsideredghmedicallyghtherapeutic
7. Prescription:g h -ghConsideredghpotentiallyghaddictiveghorghtooghharmfulghforghself-administration
- AghqualifiedghHCPghwithghlegalghauthorityghmustghauthorizeghtheghclientghtoghreceiveghtheghdrug
8. Overghtheghcountergh(OTC):ghDoghnotghrequireghprescription.
- Clientsghmayghtreatghthemselvesghsafelyghifghinstructionsghareghcarefullyghfollowed
9. CanadianghDrugghRegulationsghwereghcreatedghto...:gh-ghProtectghpublicghfromghdrugghmisuse
- Provideghmechanismghforghqualityghassuranceghforghsafetyghandgheflcacy
10. Canadiang h Drugg h Regulationsg h standardg h isg h setg h by:g h FoodghandghDrugghActghandghRegulations
11. WhatghdoesghtheghFoodghandghDrugghActghandghRegulationsghensureghsafetyghandghqu
alityghof:ghDrugs,ghbiologics,ghnaturalghhealthghproducts
12. 8ghStepsghofghDrugghApprovalghinghCanada:gh1.ghInitialghdrugghresearch
2. Pre-clinicalghstudies/investigation
3. CTAgh(clinicalghtrialghapplication)ghisghsubmittedghtoghHealthghCanadaghandghClinicalghTrialsghbeginghingh4ghphases
4. NDSgh(newghdrugghsubmission)ghtoghHealthghCanada
5. Committeeghofghdrugghexpertsgh(medicalghandghdrugghscientists)ghreviewsghNDSghtoghidentifyghbenefitsghandghrisks
6. HealthghCanadaghpassesghonghinformationghaboutghtheghdrugghtoghhealthghprovidersghandghpublicgh(consumers)
7. HealthghCanadaghissuesghNOCghandghDINgh(requiredghforghmanufacturingghandghmarketing)
8. OngoingghmonitoringghofghthegheflcacyghofghtheghdrugghandghanyghsafetyghconcernsghbyghHealthghCanada
13. 4ghClinicalghtrialghphases:ghPhasegh1:ghSafety
- Testghonghgroupghofghhealthyghpeople
Phasegh2:ghEttectiveness
- Testghonghsmallghgroupghofghpeopleghwithghtargetghillness
Phasegh3:ghConfirmation
- Testghonghlargeghgroupghofghpeopleghwithghtargetghillness
, PATgh201
- Double-blindghstudy
Phasegh4:ghMonitoring
14. Biologics:ghAgentsghthatghareghnaturallyghproducedghinghanimalghcellsghbyghmicroorganismsghorghbyghtheghbodyghitself.
- E.g.ghHormones,ghinsulin,ghgeneghtherapy,ghallergens
15. Naturalg h healthg h products:g h E.g.ghVitamins,ghsupplements,ghherbs,ghnaturalghplantghextracts
16. Classificationghofghtherapeuticghagents:ghTraditionalghdrugs,ghbiologics,ghnaturalghhealthghproducts
17. Therapeuticghclassification:ghDescribesghwhatghisghbeingghtreatedghbyghtheghdrug
- Whatghitghdoesghclinically;ghitsghtherapeuticghusefulness
18. Pharmacologicg h classification:g h Describesghhowghaghdrugghworksghatghtheghmolecular,ghtissue,ghbodyghsystemghle
vel
- Drug'sghmechanismghofghactiongh(howghaghdrugghproducesghitsghettectghinghtheghbody)
19. Prototypeghdrug:ghFirstghformghofghaghdrug
- Usedghasghaghpointghofghcomparisonghforghrelatedghversionsghofghthatghdrug
- Usedghtoghpredictghactionsghandghadverseghettectsghofghotherghdrugsghinghtheghsameghclass
20. Nomenclatureghofghdrugsgh(Chemical,ghgeneric,ghtrade):ghChemicalghnameghdescribesghchemi
calghstructureghofghaghdrug
Genericgh(nonproprietary)gh nameghdescribesgh activegh ingredientgh ofgh aghdrug
Tradegh(proprietary/brand)ghnameghisghusedghbyghcompanyghthatghproducesghaghdrug
21. Bioavailability:ghAmountghofghdrugghthatghisghabsorbedghintoghsystemicghcirculationghandghthereforeghphysiolog
icallyghavailableghtoghreachghitsghtargetghcellsghandghproduceghitsghettect
22. Drugg h Schedules:g h ScheduleghI
- Byghprescriptionghonly
ScheduleghII
- Providedghbyghpharmacist,ghkeptghinghareaghwithghnoghpublicghaccess
ScheduleghIII
- Openlyghavailableghinghaghpharmacy/pharmacyghareagh(OTC)
, PATgh201
Unscheduled
- Soldg h anywhereg h withoutg h professionalg h supervision
, PATgh201
23. Addictionghvs.ghDependence:ghAddiction:ghOverwhelmingghfeelingghthatghdrivesghaghpersonghtoghuseghaghd
rugghrepeatedly
Dependence:gh Powerfulgh physiologicalgh orgh psychologicalgh needgh forgh agh drug
24. Physicalghvs.ghpsychologicalghdependence:ghPhysical:ghAlteredghphysicalghconditionghcausedghbygh
theghnervousghsystemghadaptingghtoghrepeatedghdrugghuse
Psychological:ghFewghwithdrawalghsymptoms,ghbutghindividualghfeelsghintenseghandghcompellingghdesireghtoghcontinueghusingghtheghdru
g
25. CharacteristicsghofghanghIdealghDrug:gh-ghEttectivelyghprevents,ghtreats,ghorghcuresghcondition
- Easyghtoghadminister,ghusuallyghbyghmouth
- Producesghrapid,ghpredictableghresponseghatghlowghdoses
- Noghinteractionsghwithghfoodghorghotherghdrugs
- Takenghinfrequently,ghforghshortghlengthghofghtime
- Rapidgheliminationghafterghitghproducesghitsghbeneficialghettect
- Noghadverseghettects
- Inexpensiveghandghaccessible
26. Indications:g h Conditionsghforghwhichghaghdrugghisghapproved
27. Medicationghreconciliation:gh Processghofghkeepingghtrackghofghtheghclient'sghmedicationsghasghtheghclient'sghcare
proceedsghfromghoneghhealthghcareghproviderghtoghanother
28. Growthgh vsg h Development:g h Growth:ghProgressiveghincreaseghinghbodyghsizeghasghindividualghagesghintoghadultho
od
Development:ghFunctionalghevolutionghofghbody,ghpsychomotor,ghandghcognitiveghabilities
29. Psychology:g h Scienceghthatghdealsghwithghmentalghprocessesghandghtheirghimpactghonghbehaviour
30. Sociology:g h Studiesghhumanghbehaviourghwithinghtheghcontextghofghgroupsghandghsocieties
31. Spirituality:ghIncorporatesghcapacityghtoghlove,ghtoghconveyghcompassionghandghempathy,ghtoghgiveghandghforgive,ghtoghenjoy
life,ghandghtoghfindghpeaceghofghmindghandghfulfillmentghinghliving
32. Psychosocial:g h Interactiong h betweeng h one'sg h psychologicalg h developmentg h andg h one'sg h socialg h environment
33. Ethnicg h group:g h Communityghofghpeopleghwhoghhaveghaghcommonghhistoryghandghsimilarghgeneticghheritage
- Shareghdistinctiveghsocialghandghculturalghtraditionsghmaintainedghfromghgenerationghtoghgeneration
- Mayghincludeghsharedghperceptionghofghhealthghandghillness
1. Pharmacology:ghStudyghofghmedicines;ghhowghdrugsghimproveghorghmaintainghhealth
2. Therapeutics:g h Branchghofghmedicineghconcernedghwithghpreventionghofghdiseaseghandghtreatmentghofghsuttering.
3. Pharmacotherapeutics:ghAdministrationghofghdrugsghforgheitherghdiseaseghpreventionghorghtreatmentghandghreliefghof
suttering.
4. Drug:ghAghchemicalghagentghcapableghofghproducingghbiologicalghresponsesghwithinghtheghbody.
5. Therapeuticghvs.ghadverse:ghDesirableghvs.ghundesirable
6. Medication:g h Drugghthatghisghconsideredghmedicallyghtherapeutic
7. Prescription:g h -ghConsideredghpotentiallyghaddictiveghorghtooghharmfulghforghself-administration
- AghqualifiedghHCPghwithghlegalghauthorityghmustghauthorizeghtheghclientghtoghreceiveghtheghdrug
8. Overghtheghcountergh(OTC):ghDoghnotghrequireghprescription.
- Clientsghmayghtreatghthemselvesghsafelyghifghinstructionsghareghcarefullyghfollowed
9. CanadianghDrugghRegulationsghwereghcreatedghto...:gh-ghProtectghpublicghfromghdrugghmisuse
- Provideghmechanismghforghqualityghassuranceghforghsafetyghandgheflcacy
10. Canadiang h Drugg h Regulationsg h standardg h isg h setg h by:g h FoodghandghDrugghActghandghRegulations
11. WhatghdoesghtheghFoodghandghDrugghActghandghRegulationsghensureghsafetyghandghqu
alityghof:ghDrugs,ghbiologics,ghnaturalghhealthghproducts
12. 8ghStepsghofghDrugghApprovalghinghCanada:gh1.ghInitialghdrugghresearch
2. Pre-clinicalghstudies/investigation
3. CTAgh(clinicalghtrialghapplication)ghisghsubmittedghtoghHealthghCanadaghandghClinicalghTrialsghbeginghingh4ghphases
4. NDSgh(newghdrugghsubmission)ghtoghHealthghCanada
5. Committeeghofghdrugghexpertsgh(medicalghandghdrugghscientists)ghreviewsghNDSghtoghidentifyghbenefitsghandghrisks
6. HealthghCanadaghpassesghonghinformationghaboutghtheghdrugghtoghhealthghprovidersghandghpublicgh(consumers)
7. HealthghCanadaghissuesghNOCghandghDINgh(requiredghforghmanufacturingghandghmarketing)
8. OngoingghmonitoringghofghthegheflcacyghofghtheghdrugghandghanyghsafetyghconcernsghbyghHealthghCanada
13. 4ghClinicalghtrialghphases:ghPhasegh1:ghSafety
- Testghonghgroupghofghhealthyghpeople
Phasegh2:ghEttectiveness
- Testghonghsmallghgroupghofghpeopleghwithghtargetghillness
Phasegh3:ghConfirmation
- Testghonghlargeghgroupghofghpeopleghwithghtargetghillness
, PATgh201
- Double-blindghstudy
Phasegh4:ghMonitoring
14. Biologics:ghAgentsghthatghareghnaturallyghproducedghinghanimalghcellsghbyghmicroorganismsghorghbyghtheghbodyghitself.
- E.g.ghHormones,ghinsulin,ghgeneghtherapy,ghallergens
15. Naturalg h healthg h products:g h E.g.ghVitamins,ghsupplements,ghherbs,ghnaturalghplantghextracts
16. Classificationghofghtherapeuticghagents:ghTraditionalghdrugs,ghbiologics,ghnaturalghhealthghproducts
17. Therapeuticghclassification:ghDescribesghwhatghisghbeingghtreatedghbyghtheghdrug
- Whatghitghdoesghclinically;ghitsghtherapeuticghusefulness
18. Pharmacologicg h classification:g h Describesghhowghaghdrugghworksghatghtheghmolecular,ghtissue,ghbodyghsystemghle
vel
- Drug'sghmechanismghofghactiongh(howghaghdrugghproducesghitsghettectghinghtheghbody)
19. Prototypeghdrug:ghFirstghformghofghaghdrug
- Usedghasghaghpointghofghcomparisonghforghrelatedghversionsghofghthatghdrug
- Usedghtoghpredictghactionsghandghadverseghettectsghofghotherghdrugsghinghtheghsameghclass
20. Nomenclatureghofghdrugsgh(Chemical,ghgeneric,ghtrade):ghChemicalghnameghdescribesghchemi
calghstructureghofghaghdrug
Genericgh(nonproprietary)gh nameghdescribesgh activegh ingredientgh ofgh aghdrug
Tradegh(proprietary/brand)ghnameghisghusedghbyghcompanyghthatghproducesghaghdrug
21. Bioavailability:ghAmountghofghdrugghthatghisghabsorbedghintoghsystemicghcirculationghandghthereforeghphysiolog
icallyghavailableghtoghreachghitsghtargetghcellsghandghproduceghitsghettect
22. Drugg h Schedules:g h ScheduleghI
- Byghprescriptionghonly
ScheduleghII
- Providedghbyghpharmacist,ghkeptghinghareaghwithghnoghpublicghaccess
ScheduleghIII
- Openlyghavailableghinghaghpharmacy/pharmacyghareagh(OTC)
, PATgh201
Unscheduled
- Soldg h anywhereg h withoutg h professionalg h supervision
, PATgh201
23. Addictionghvs.ghDependence:ghAddiction:ghOverwhelmingghfeelingghthatghdrivesghaghpersonghtoghuseghaghd
rugghrepeatedly
Dependence:gh Powerfulgh physiologicalgh orgh psychologicalgh needgh forgh agh drug
24. Physicalghvs.ghpsychologicalghdependence:ghPhysical:ghAlteredghphysicalghconditionghcausedghbygh
theghnervousghsystemghadaptingghtoghrepeatedghdrugghuse
Psychological:ghFewghwithdrawalghsymptoms,ghbutghindividualghfeelsghintenseghandghcompellingghdesireghtoghcontinueghusingghtheghdru
g
25. CharacteristicsghofghanghIdealghDrug:gh-ghEttectivelyghprevents,ghtreats,ghorghcuresghcondition
- Easyghtoghadminister,ghusuallyghbyghmouth
- Producesghrapid,ghpredictableghresponseghatghlowghdoses
- Noghinteractionsghwithghfoodghorghotherghdrugs
- Takenghinfrequently,ghforghshortghlengthghofghtime
- Rapidgheliminationghafterghitghproducesghitsghbeneficialghettect
- Noghadverseghettects
- Inexpensiveghandghaccessible
26. Indications:g h Conditionsghforghwhichghaghdrugghisghapproved
27. Medicationghreconciliation:gh Processghofghkeepingghtrackghofghtheghclient'sghmedicationsghasghtheghclient'sghcare
proceedsghfromghoneghhealthghcareghproviderghtoghanother
28. Growthgh vsg h Development:g h Growth:ghProgressiveghincreaseghinghbodyghsizeghasghindividualghagesghintoghadultho
od
Development:ghFunctionalghevolutionghofghbody,ghpsychomotor,ghandghcognitiveghabilities
29. Psychology:g h Scienceghthatghdealsghwithghmentalghprocessesghandghtheirghimpactghonghbehaviour
30. Sociology:g h Studiesghhumanghbehaviourghwithinghtheghcontextghofghgroupsghandghsocieties
31. Spirituality:ghIncorporatesghcapacityghtoghlove,ghtoghconveyghcompassionghandghempathy,ghtoghgiveghandghforgive,ghtoghenjoy
life,ghandghtoghfindghpeaceghofghmindghandghfulfillmentghinghliving
32. Psychosocial:g h Interactiong h betweeng h one'sg h psychologicalg h developmentg h andg h one'sg h socialg h environment
33. Ethnicg h group:g h Communityghofghpeopleghwhoghhaveghaghcommonghhistoryghandghsimilarghgeneticghheritage
- Shareghdistinctiveghsocialghandghculturalghtraditionsghmaintainedghfromghgenerationghtoghgeneration
- Mayghincludeghsharedghperceptionghofghhealthghandghillness
