NURS 5334 - ANTIMICROBIAL RECALL
CORRECT 100%
Why do many medications lack pediatric dosing information in their drug labeling -
ANSWERThere is lack of evidence-based literature on the safe and effective use of
medications in children
Why are neonates at greater risk for toxicity with highly protein-bound drugs -
ANSWERProtein binding is decreased in neonates increasing the amount of free drug
available
At what age are adult levels of renal function achieved - ANSWER12 months
What is the most accurate device for measuring a 2.5mL dose for a child - ANSWERAn
oral syringe
How do you help prevent medication errors - ANSWERWrite out the term daily
In pediatric patients gastric acidity does not reach adult values for - ANSWER2 years
Nalidixic acid may cause _______ in children - ANSWERcartilage erosion
Altered absorption of drugs in the elderly may result in _______ drug response -
ANSWERDelayed
You have an elderly patient taking warfarin. You add another protein binding drug.
Which of the following statements is correct? - ANSWERYou will need to decrease dose
of warfarin
In elderly, proper index of renal function is _____ - ANSWERGlomerular filtration rate
(GFR)
List that identifies drugs with high likelihood of cause adverse effects in elderly -
ANSWERBeers list
Primary mechanism of antibacterial action of the penicillin's involve inhibition of -
ANSWERCell wall synthesis by binding and inactivating penicillin binding proteins
(PBPs)
Which statement about vancomycin is accurate - ANSWERIncreases bacterial cell wall
permeability and inhibits RNA synthesis
The mechanism of action of the tetracyclines involves - ANSWERInhibiting protein
synthesis
, Mechanism of action of aminoglycosides - ANSWERCauses misreading of the code on
the mRNA template to inhibit protein synthesis
Which statement is accurate regarding the antibacterial action of gentamicin -
ANSWERGentamicin continues to exert antibacterial effects even after plasma level
decrease below detectable levels
If a patient was treated with the macrolide erythromycin, he/she should -
ANSWERTemporarily stop simvastatin while taking erythromycin
24 year old woman returned from vacation abroad suffering from traveler's diarrhea, and
her problem has not responded to antidiarrheal drugs. A pathogenic gram-negative
bacillus is suspected. Which drug is most likely to be effective in the treatment of this
patient - ANSWERCiprofloxacin
Which is accurate about fluoroquinolones - ANSWERFluoroquinolones have different
therapeutic applications depending on the generation
Which adverse effect is MOST LIKELY to occur with sulfonamides - ANSWERSkin
reactions
Which is true about ciprofloxacin - ANSWERDuring treatment, tendonitis and even
tendon rupture may occur
Primary reason for the use of drug combinations in treatment of TB is to -
ANSWERDelay or prevent emergence of resistance
Which is true about fluconazole - ANSWERPrimary route of excretion is renal
55 year old man has been on anticoagulant treatment for many years and is newly
diagnosed with TB. Which of the following antimycobacterial agents would MOST
LIKELY induce cytochrome P450 enzymes in the patient's liver thereby modifying the
effects of his anticoagulant treatment - ANSWERRifampin
Which drug is an antiviral that can be used to decrease shedding with genital herpes -
ANSWERValacyclovir
First generation cephalosporins are best against which organism - ANSWERGram
positive cocci
Cefepime is eliminated via - ANSWERTubular secretion and or glomerular filtration
Which cephalosporins cause bleeding tendencies - ANSWERcefotetan and ceftriaxone
Which cephalosporins induce alcohol intolerance - ANSWERCefotetan and Cefazolin
CORRECT 100%
Why do many medications lack pediatric dosing information in their drug labeling -
ANSWERThere is lack of evidence-based literature on the safe and effective use of
medications in children
Why are neonates at greater risk for toxicity with highly protein-bound drugs -
ANSWERProtein binding is decreased in neonates increasing the amount of free drug
available
At what age are adult levels of renal function achieved - ANSWER12 months
What is the most accurate device for measuring a 2.5mL dose for a child - ANSWERAn
oral syringe
How do you help prevent medication errors - ANSWERWrite out the term daily
In pediatric patients gastric acidity does not reach adult values for - ANSWER2 years
Nalidixic acid may cause _______ in children - ANSWERcartilage erosion
Altered absorption of drugs in the elderly may result in _______ drug response -
ANSWERDelayed
You have an elderly patient taking warfarin. You add another protein binding drug.
Which of the following statements is correct? - ANSWERYou will need to decrease dose
of warfarin
In elderly, proper index of renal function is _____ - ANSWERGlomerular filtration rate
(GFR)
List that identifies drugs with high likelihood of cause adverse effects in elderly -
ANSWERBeers list
Primary mechanism of antibacterial action of the penicillin's involve inhibition of -
ANSWERCell wall synthesis by binding and inactivating penicillin binding proteins
(PBPs)
Which statement about vancomycin is accurate - ANSWERIncreases bacterial cell wall
permeability and inhibits RNA synthesis
The mechanism of action of the tetracyclines involves - ANSWERInhibiting protein
synthesis
, Mechanism of action of aminoglycosides - ANSWERCauses misreading of the code on
the mRNA template to inhibit protein synthesis
Which statement is accurate regarding the antibacterial action of gentamicin -
ANSWERGentamicin continues to exert antibacterial effects even after plasma level
decrease below detectable levels
If a patient was treated with the macrolide erythromycin, he/she should -
ANSWERTemporarily stop simvastatin while taking erythromycin
24 year old woman returned from vacation abroad suffering from traveler's diarrhea, and
her problem has not responded to antidiarrheal drugs. A pathogenic gram-negative
bacillus is suspected. Which drug is most likely to be effective in the treatment of this
patient - ANSWERCiprofloxacin
Which is accurate about fluoroquinolones - ANSWERFluoroquinolones have different
therapeutic applications depending on the generation
Which adverse effect is MOST LIKELY to occur with sulfonamides - ANSWERSkin
reactions
Which is true about ciprofloxacin - ANSWERDuring treatment, tendonitis and even
tendon rupture may occur
Primary reason for the use of drug combinations in treatment of TB is to -
ANSWERDelay or prevent emergence of resistance
Which is true about fluconazole - ANSWERPrimary route of excretion is renal
55 year old man has been on anticoagulant treatment for many years and is newly
diagnosed with TB. Which of the following antimycobacterial agents would MOST
LIKELY induce cytochrome P450 enzymes in the patient's liver thereby modifying the
effects of his anticoagulant treatment - ANSWERRifampin
Which drug is an antiviral that can be used to decrease shedding with genital herpes -
ANSWERValacyclovir
First generation cephalosporins are best against which organism - ANSWERGram
positive cocci
Cefepime is eliminated via - ANSWERTubular secretion and or glomerular filtration
Which cephalosporins cause bleeding tendencies - ANSWERcefotetan and ceftriaxone
Which cephalosporins induce alcohol intolerance - ANSWERCefotetan and Cefazolin
