and answers Graded A+
what can happen to individuals with chronic illness when they travel abroad
exacerbation of illnesses, no access to medications
who does pretravel consultation and when is it ideally done?
infectious disease specialists, 6-8 weeks before travel
important resources for travel medicine
WHO and yellow book
drug prophylaxis options for travelers to areas with p. falciparum that is
RESISTANT to chloroquines
atovaquone-proguanil, mefloquine, doxycycline, tefenoquine
drug prophylaxis options for travelers to areas with p. falciparum that is
SENSITIVE to chloroquines
chloroquine phosphate, hydroxychloroquine sulfate
prophylaxis with atovaquone-proguanil: when to initiate treatment and
contraindications
initiate: 1-2 days before
contraindications: pregnant, breastfeeding infant <5kg, <5kg, severe renal disease
prophylaxis with mefloquine hydrochloride: when to initiate treatment and
contraindications
initiate: 3 weeks before, 2 weeks acceptable
contraindications: neuropsych disorder, seizures, cardiac conduction disorders
prophylaxis with doxycycline: when to initiate treatment and contraindications
initiate: 1-2 days before
contraindications: pregnancy, children <8 yrs
prophylaxis with tefenoquine: when to initiate treatment and contraindications
, initiate: loading dose 3 days before trip<
contraindications: pregnant, psych disorder, G6PD deficiency/breastfeeding infant
w/ unknown/confirmed G6PD status
prophylaxis with chloroquine phosphate: when to initiate treatment and
contraindications
initiate: 1-2 weeks before
contraindications: allergy
prophylaxis with hydroxychloroquine sulfate: when to initiate treatment and
contraindications
initiate: 1-2 weeks before
contraindications: allergy
are chloroquines often used for malaria prophylaxis anymore?
no due to risk of resistance
drug prophylaxis option for travelers to areas with p. vivax? when to initiate and
contraindications
primaquine 1-2 days before
contraindications: pregnant, G6PD deficiency/breastfeeding infant with
unknown/confirmed G6PD status
travel specific vaccines needed based on destination and risk factors (besides flu
and covid vaccines)
hep a, bcg, cholera, japanese encephalitis, meningococcal, rabies, tick borne
encephalitis, typhoid, yellow fever
common pathogens that cause travelers diarrhea
enterogenic E. coli, enteroaggregative E. coli, campylobacter jejuni, norovirus
functional definition of mild travelers diarrhea
tolerable, not distressing, does not interfere with travel activities
functional definition of moderate travelers diarrhea
distressing/interferes with travel activities