Affinity - ANS-the propensity of a ligand to bind to a receptor
Agonist - ANS-has affinity for a receptor as well as intrinsic activity on the receptor
Antagonist - ANS-has affinity for a receptor however no intrinsic activity on the receptor
Bioavailability (F) - ANS-quantity of drug in systemic circulate/quantity of drug administered
EC50 - ANS-dose that elicits 50% of the maximal reaction
Emax - ANS-maximum impact of a drug
Growth factors and insulin are worried in which type of receptor? - ANS-Coupled to Enzyme
Receptors
high affinity = - ANS-binds simply to a receptor
How can unique components of food (like minerals) have an effect on absorption? -
ANS-minerals can bind to pills and reduce their absorption
If a patient were to overdose on a reversible antagonist, what should you do? - ANS-Add more
agonist
intrinsic interest - ANS-the motion carried out by means of the ligand whilst it's far certain to a
receptor
inverse agonist - ANS-binds to a constitutively lively receptor and inactivates it
Irreversible or Non-Competitive Antagonists - ANS-bind to receptor for lifestyles
Kd - ANS-dissociation consistent (affinity of a drug for a receptor)
low affinity = - ANS-spends less time bound to a given receptor
partial agonist - ANS-has affinity for a receptor however lacks the entire intrinsic hobby of an
agonist
Quantal dose-response curve - ANS-Plots the cumulative frequency of responses at a given
dose
Receptor - ANS-Macromolecule whose organic characteristic modifications when a drug binds
to it
Agonist - ANS-has affinity for a receptor as well as intrinsic activity on the receptor
Antagonist - ANS-has affinity for a receptor however no intrinsic activity on the receptor
Bioavailability (F) - ANS-quantity of drug in systemic circulate/quantity of drug administered
EC50 - ANS-dose that elicits 50% of the maximal reaction
Emax - ANS-maximum impact of a drug
Growth factors and insulin are worried in which type of receptor? - ANS-Coupled to Enzyme
Receptors
high affinity = - ANS-binds simply to a receptor
How can unique components of food (like minerals) have an effect on absorption? -
ANS-minerals can bind to pills and reduce their absorption
If a patient were to overdose on a reversible antagonist, what should you do? - ANS-Add more
agonist
intrinsic interest - ANS-the motion carried out by means of the ligand whilst it's far certain to a
receptor
inverse agonist - ANS-binds to a constitutively lively receptor and inactivates it
Irreversible or Non-Competitive Antagonists - ANS-bind to receptor for lifestyles
Kd - ANS-dissociation consistent (affinity of a drug for a receptor)
low affinity = - ANS-spends less time bound to a given receptor
partial agonist - ANS-has affinity for a receptor however lacks the entire intrinsic hobby of an
agonist
Quantal dose-response curve - ANS-Plots the cumulative frequency of responses at a given
dose
Receptor - ANS-Macromolecule whose organic characteristic modifications when a drug binds
to it
