Which of the following studies should be completed at regular intervals for a patient receiv-
ing long-term steroids?
A. Positron emission tomography scan
B. Magnetic resonance imaging
C. Dual energy x-ray absorptiometry
D. Computed tomography scan - ANSWER C. Dual energy x-ray absorptiometry
The major histocompatibility complex is responsible for:
A. identification of self versus non-self.
B. the release of histamine during a hemolytic transfusion reaction.
C. the release of hematopoietic stem cells from the bone marrow.
D. progenitor cell Golgi complex regulation. - ANSWER A. identification of self versus non-
self.
What is the overall grade of acute graft-versus-host disease for a patient following transplant
who has a maculopapular rash on the face and trunk, a direct bilirubin of 4 mg/dL, and ap-
proximately 1,200 mL/day of diarrhea?
A. III
B. IV
C. I
D. II - ANSWER A. III
1
,Maculopapular rash 40.5% = grade 2
Bilirubin 4 mg/dL = grade 2
Diarrhea 1,200 mL/day = grade 2
What preventive measures can help reduce the occurrence of acute graft-versus-host dis-
ease?
A. Using ABO-compatible donors
B. Administering hematopoietic growth factor post-transplant
C. Administering alemtuzumab and fludarabine
D. Irradiating the stem cell product prior to infusion - ANSWER C. Administering
alemtuzumab and fludarabine
Which of the following should be considered prior to administering a myeloablative condi-
tioning regimen?
A. Patient's gender
B. Patient's disease
C. Donor's age
D. Donor's ethnicity - ANSWER B. Patient's disease
A patient is currently taking cyclosporine and has a new order for fluconazole. The nurse an-
ticipates which of the following?
A. Administering medications at separate times
B. Suspecting blood medication levels will be inaccurate
C. Increasing the dose of fluconazole
D. Reducing the dose of cyclosporine - ANSWER D. Reducing the dose of cyclosporine
2
, Which secondary malignancy is a patient most at risk for developing following an allogeneic
HSCT?
A. Colorectal cancer
B. Chronic myeloid leukemia
C. Ewing sarcoma
D. Post-transplant lymphroproliferative disease - ANSWER D. Post-transplant lymphropro-
liferative disease
Minutes after a cryopreserved stem cell infusion is initiated, a patient develops a cough and
mild wheezing. The nurse should next:
A. decrease the hydration rate.
B. slow the infusion.
C. administer IM epinephrine.
D. obtain an order for chest x-ray. - ANSWER B. slow the infusion.
Which of the following actions should the nurse take prior to collecting autologous stem
cells for a young child?
A. Obtaining additional peripheral IV access
B. Inserting a urinary catheter on the days of collection
C. Priming the machine with irradiated packed red blood cells
D. Decreasing the dose of filgrastim - ANSWER C. Priming the machine with irradiated
packed red blood cells
Nonmyeloablative allogeneic hematopoietic stem cell transplantation was developed as a
treatment option for patients who:
3
ing long-term steroids?
A. Positron emission tomography scan
B. Magnetic resonance imaging
C. Dual energy x-ray absorptiometry
D. Computed tomography scan - ANSWER C. Dual energy x-ray absorptiometry
The major histocompatibility complex is responsible for:
A. identification of self versus non-self.
B. the release of histamine during a hemolytic transfusion reaction.
C. the release of hematopoietic stem cells from the bone marrow.
D. progenitor cell Golgi complex regulation. - ANSWER A. identification of self versus non-
self.
What is the overall grade of acute graft-versus-host disease for a patient following transplant
who has a maculopapular rash on the face and trunk, a direct bilirubin of 4 mg/dL, and ap-
proximately 1,200 mL/day of diarrhea?
A. III
B. IV
C. I
D. II - ANSWER A. III
1
,Maculopapular rash 40.5% = grade 2
Bilirubin 4 mg/dL = grade 2
Diarrhea 1,200 mL/day = grade 2
What preventive measures can help reduce the occurrence of acute graft-versus-host dis-
ease?
A. Using ABO-compatible donors
B. Administering hematopoietic growth factor post-transplant
C. Administering alemtuzumab and fludarabine
D. Irradiating the stem cell product prior to infusion - ANSWER C. Administering
alemtuzumab and fludarabine
Which of the following should be considered prior to administering a myeloablative condi-
tioning regimen?
A. Patient's gender
B. Patient's disease
C. Donor's age
D. Donor's ethnicity - ANSWER B. Patient's disease
A patient is currently taking cyclosporine and has a new order for fluconazole. The nurse an-
ticipates which of the following?
A. Administering medications at separate times
B. Suspecting blood medication levels will be inaccurate
C. Increasing the dose of fluconazole
D. Reducing the dose of cyclosporine - ANSWER D. Reducing the dose of cyclosporine
2
, Which secondary malignancy is a patient most at risk for developing following an allogeneic
HSCT?
A. Colorectal cancer
B. Chronic myeloid leukemia
C. Ewing sarcoma
D. Post-transplant lymphroproliferative disease - ANSWER D. Post-transplant lymphropro-
liferative disease
Minutes after a cryopreserved stem cell infusion is initiated, a patient develops a cough and
mild wheezing. The nurse should next:
A. decrease the hydration rate.
B. slow the infusion.
C. administer IM epinephrine.
D. obtain an order for chest x-ray. - ANSWER B. slow the infusion.
Which of the following actions should the nurse take prior to collecting autologous stem
cells for a young child?
A. Obtaining additional peripheral IV access
B. Inserting a urinary catheter on the days of collection
C. Priming the machine with irradiated packed red blood cells
D. Decreasing the dose of filgrastim - ANSWER C. Priming the machine with irradiated
packed red blood cells
Nonmyeloablative allogeneic hematopoietic stem cell transplantation was developed as a
treatment option for patients who:
3
