which of the following is an example of a myeloid cell?
A) thymus-derived cells (T cells)
B) bone marrow- derived cells (B cells)
C) monocytes
D) natural killer cells - ANSWER C
Which factor does not affect immune reconstitution following hematopoietic stem cell trans-
plantation?
A) the recipient's response of the conditioning regimen
B) viral infections
C) chronic GVHD
D) longevity of mature lymphocytes present at the time of transplant - ANSWER B
- its is delayed in pts with chronic GVHD
Hematopoiesis occurs primarily in which area?
A) bone marrow
B) spleen
C) thymus gland
D) lymph nodes - ANSWER A
1
,Which of the following statements is true about innate immunity?
A) it occurs in response to T cell activation
B) it occurs in response to B cell activation
C) it is a natural process that uses phagocytes that release inflammatory mediators in re-
sponse to infections or illness
D) it is a natural process that occurs primarily in the spleen - ANSWER C
-acquired immunity is the response of either B or T cells to antigens
Which is not a common indication for allogeneic transplantation?
A) acute myeloid leukemia
B) myelodysplastic syndrome
C) chronic myeloid leukemia
D) breast cancer - ANSWER D
Graft-versus-tumor effect is promoted by which of the following?
A) withdrawal of immunosuppressive therapy
B) administration of donor lymphocyte infusion
C) A and B
D) increased dose of immunosuppressive therapy - ANSWER C
Which of the following is not a role of caregiver?
A) provide physical and emotional support
2
, b) assist with recovery following hematopoietic stem cell transplantation
C) assist with medication administration
D) recommend over the counter medications for the management of post-transplant symp-
toms - ANSWER D
which option best outlines the process of autologous stem cell transplantation?
A) stem cell mobilization and collection, reinfusion of autologous stem cells, and administra-
tion of high-dose chemotherapy
B) disease reassessment to determine remission status; stem cell mobilization, collection,
and cryopreservation; administration of a conditioning regimen; verification of stem cell via-
bility; and reinfusion of autologous stem cells
C) stem cell mobilization, collection and cryopreservation; administration of conditioning
regimen; and reinfusion of autologous stem cells
D) disease reassessment to determine remission status; stem cell mobilization, collection,
and cryopreservation; administration of conditioning regimen; verification of stem cell viabil-
ity; and reinfusion of allogeneic stem cells - ANSWER B
Which treatment allows for greater use of haploidentical stem cell transplants?
A) donor lymphocyte infusion
B) pretransplant cyclophosphamides
C) graft versus host treatment
D) post transplant cyclophosphamide - ANSWER D
this depletes alloreactive T cells; research has demonstrated haploidentical HSCT now
achieves the same overall survival as transplants from unrelated donors
A patient is receiving an allogeneic stem cell transplant to treat acute myeloid leukemia.
Which is not a donor option for this treatment?
3
A) thymus-derived cells (T cells)
B) bone marrow- derived cells (B cells)
C) monocytes
D) natural killer cells - ANSWER C
Which factor does not affect immune reconstitution following hematopoietic stem cell trans-
plantation?
A) the recipient's response of the conditioning regimen
B) viral infections
C) chronic GVHD
D) longevity of mature lymphocytes present at the time of transplant - ANSWER B
- its is delayed in pts with chronic GVHD
Hematopoiesis occurs primarily in which area?
A) bone marrow
B) spleen
C) thymus gland
D) lymph nodes - ANSWER A
1
,Which of the following statements is true about innate immunity?
A) it occurs in response to T cell activation
B) it occurs in response to B cell activation
C) it is a natural process that uses phagocytes that release inflammatory mediators in re-
sponse to infections or illness
D) it is a natural process that occurs primarily in the spleen - ANSWER C
-acquired immunity is the response of either B or T cells to antigens
Which is not a common indication for allogeneic transplantation?
A) acute myeloid leukemia
B) myelodysplastic syndrome
C) chronic myeloid leukemia
D) breast cancer - ANSWER D
Graft-versus-tumor effect is promoted by which of the following?
A) withdrawal of immunosuppressive therapy
B) administration of donor lymphocyte infusion
C) A and B
D) increased dose of immunosuppressive therapy - ANSWER C
Which of the following is not a role of caregiver?
A) provide physical and emotional support
2
, b) assist with recovery following hematopoietic stem cell transplantation
C) assist with medication administration
D) recommend over the counter medications for the management of post-transplant symp-
toms - ANSWER D
which option best outlines the process of autologous stem cell transplantation?
A) stem cell mobilization and collection, reinfusion of autologous stem cells, and administra-
tion of high-dose chemotherapy
B) disease reassessment to determine remission status; stem cell mobilization, collection,
and cryopreservation; administration of a conditioning regimen; verification of stem cell via-
bility; and reinfusion of autologous stem cells
C) stem cell mobilization, collection and cryopreservation; administration of conditioning
regimen; and reinfusion of autologous stem cells
D) disease reassessment to determine remission status; stem cell mobilization, collection,
and cryopreservation; administration of conditioning regimen; verification of stem cell viabil-
ity; and reinfusion of allogeneic stem cells - ANSWER B
Which treatment allows for greater use of haploidentical stem cell transplants?
A) donor lymphocyte infusion
B) pretransplant cyclophosphamides
C) graft versus host treatment
D) post transplant cyclophosphamide - ANSWER D
this depletes alloreactive T cells; research has demonstrated haploidentical HSCT now
achieves the same overall survival as transplants from unrelated donors
A patient is receiving an allogeneic stem cell transplant to treat acute myeloid leukemia.
Which is not a donor option for this treatment?
3
