NURS 5334 Exam 2 (Advanced Pharmacology) Assessment
Practice Questions and Answers
1.
Question: A patient with asthma is prescribed a β2-adrenergic agonist. Which effect is
expected?
A. Bronchoconstriction
B. Bronchodilation
C. Increased mucus secretion
D. Decreased heart rate
Answer: B. Bronchodilation
Rationale: β2 agonists stimulate smooth muscle relaxation in the bronchi, improving
airflow.
2.
Question: Which drug class is first-line for hypertension in African American patients
without CKD?
A. ACE inhibitors
B. Thiazide diuretics
C. Beta-blockers
D. ARBs
Answer: B. Thiazide diuretics
Rationale: Evidence shows thiazides and calcium channel blockers are more effective in
this population.
3.
Question: Which insulin has the fastest onset?
A. Regular insulin
B. NPH
C. Lispro
D. Glargine
Answer: C. Lispro
Rationale: Lispro is rapid-acting, onset within 15 minutes, ideal for mealtime coverage.
4.
Question: A patient on warfarin has INR 5.2 but no bleeding. Next step?
A. Continue same dose
B. Hold warfarin, monitor INR
C. Administer vitamin K immediately
D. Increase warfarin dose
Answer: B. Hold warfarin, monitor INR
Rationale: INR >5 but <9 without bleeding → hold dose, monitor closely.
5.
Question: Which antibiotic is contraindicated in pregnancy?
A. Amoxicillin
, B. Tetracycline
C. Cephalexin
D. Azithromycin
Answer: B. Tetracycline
Rationale: Causes fetal bone/teeth abnormalities.
6.
Question: Which drug is most effective for acute angina relief?
A. Metoprolol
B. Nitroglycerin
C. Verapamil
D. Digoxin
Answer: B. Nitroglycerin
Rationale: Rapid vasodilation decreases myocardial oxygen demand.
7.
Question: Which lab must be monitored with ACE inhibitors?
A. Platelets
B. Potassium
C. Hemoglobin
D. Calcium
Answer: B. Potassium
Rationale: ACE inhibitors can cause hyperkalemia.
8.
Question: Which drug is first-line for Type 2 Diabetes?
A. Insulin
B. Metformin
C. Sulfonylurea
D. Pioglitazone
Answer: B. Metformin
Rationale: Improves insulin sensitivity, weight neutral, safe unless renal impairment.
9.
Question: Which opioid antagonist reverses respiratory depression?
A. Naloxone
B. Morphine
C. Methadone
D. Buprenorphine
Answer: A. Naloxone
Rationale: Competitive antagonist at opioid receptors.
10.
Question: Which drug is contraindicated in asthma?
A. Albuterol
B. Metoprolol
Practice Questions and Answers
1.
Question: A patient with asthma is prescribed a β2-adrenergic agonist. Which effect is
expected?
A. Bronchoconstriction
B. Bronchodilation
C. Increased mucus secretion
D. Decreased heart rate
Answer: B. Bronchodilation
Rationale: β2 agonists stimulate smooth muscle relaxation in the bronchi, improving
airflow.
2.
Question: Which drug class is first-line for hypertension in African American patients
without CKD?
A. ACE inhibitors
B. Thiazide diuretics
C. Beta-blockers
D. ARBs
Answer: B. Thiazide diuretics
Rationale: Evidence shows thiazides and calcium channel blockers are more effective in
this population.
3.
Question: Which insulin has the fastest onset?
A. Regular insulin
B. NPH
C. Lispro
D. Glargine
Answer: C. Lispro
Rationale: Lispro is rapid-acting, onset within 15 minutes, ideal for mealtime coverage.
4.
Question: A patient on warfarin has INR 5.2 but no bleeding. Next step?
A. Continue same dose
B. Hold warfarin, monitor INR
C. Administer vitamin K immediately
D. Increase warfarin dose
Answer: B. Hold warfarin, monitor INR
Rationale: INR >5 but <9 without bleeding → hold dose, monitor closely.
5.
Question: Which antibiotic is contraindicated in pregnancy?
A. Amoxicillin
, B. Tetracycline
C. Cephalexin
D. Azithromycin
Answer: B. Tetracycline
Rationale: Causes fetal bone/teeth abnormalities.
6.
Question: Which drug is most effective for acute angina relief?
A. Metoprolol
B. Nitroglycerin
C. Verapamil
D. Digoxin
Answer: B. Nitroglycerin
Rationale: Rapid vasodilation decreases myocardial oxygen demand.
7.
Question: Which lab must be monitored with ACE inhibitors?
A. Platelets
B. Potassium
C. Hemoglobin
D. Calcium
Answer: B. Potassium
Rationale: ACE inhibitors can cause hyperkalemia.
8.
Question: Which drug is first-line for Type 2 Diabetes?
A. Insulin
B. Metformin
C. Sulfonylurea
D. Pioglitazone
Answer: B. Metformin
Rationale: Improves insulin sensitivity, weight neutral, safe unless renal impairment.
9.
Question: Which opioid antagonist reverses respiratory depression?
A. Naloxone
B. Morphine
C. Methadone
D. Buprenorphine
Answer: A. Naloxone
Rationale: Competitive antagonist at opioid receptors.
10.
Question: Which drug is contraindicated in asthma?
A. Albuterol
B. Metoprolol
