HESI PHARMACOLOGY COMPREHENSIVE EXIT RN EXAM 2025-2026
HESI Pharmacology Comprehensive Exit RN
Exam 2025-2026 | Actual RN Exam With
Verified 170 Questions And Correct Answers
| Already Graded A+
HESI PHARMACOLOGY EXIT RN EXAM 2025–
2026
ACTUAL EXAM 170 QUESTIONS AND CORRECT ANSWERS | ALREADY GRADED
A+ | BRAND NEW!!
Overview
The HESI Pharmacology Exit RN Exam 2025–2026 Study Guide provides a
comprehensive and evidence-based review of essential medication knowledge
required for nursing practice. This exam preparation resource focuses on
pharmacologic principles, safe medication administration, and clinical
decision-making skills necessary for modern nursing care.
Covering critical topics such as drug classifications, therapeutic uses,
mechanisms of action, adverse reactions, dosage calculations, and nursing
interventions, this guide strengthens both theoretical knowledge and practical
application. Structured in a true HESI-style exam format, it supports nursing
students in developing the confidence and competence required to succeed on
the HESI Pharmacology Exit Exam and the Next Generation NCLEX (NGN).
Key Features
✓ 170 Verified HESI Pharmacology Exam Questions with Correct Answers
✓ Aligned with 2025–2026 HESI and NCLEX-RN Testing Standards
✓ A+ Graded and Expert-Reviewed for 100% Accuracy
✓ Realistic Exam Format for Authentic Practice
✓ Comprehensive Coverage of Pharmacology and Medication Safety
Page 1 of 22
,HESI PHARMACOLOGY COMPREHENSIVE EXIT RN EXAM 2025-2026
1.
A male client with stomach cancer returns to the unit following a total
gastrectomy. He has a nasogastric tube to suction and is receiving Lactated
Ringer's solution at 75 mL/hour IV. One hour after admission, the nurse notes
300 mL of blood in the suction canister, heart rate 155 beats/minute, and
blood pressure 78/48 mmHg. Which action should the nurse implement first?
Correct Answer: Increase the infusion rate of Lactated Ringer’s solution.
2.
An adult male who fell 20 feet from the roof of his home has multiple injuries
including a right pneumothorax. Chest tubes were inserted prior to transfer to
the ICU. The nurse observes bubbling in the suction control chamber and
fluctuation in the water seal chamber. Which intervention should the nurse
implement?
Correct Answer: Add sterile water to the suction control chamber.
3.
A client who received hemodialysis yesterday is experiencing blood pressure
of 200/100 mmHg, heart rate 110 beats/minute, respiratory rate 36
breaths/minute, and oxygen saturation of 89% on room air. Which action
should the nurse take first?
Correct Answer: Begin supplemental oxygen.
4.
A client with Addison’s crisis is admitted for treatment with adrenal
corticosteroids. Which findings require immediate nursing action? (Select all
that apply.)
Correct Answer: Irregular heart rate, pallor, tremors, and diaphoresis.
5.
An older client is admitted with dehydration and fluid volume deficit. Which
assessment finding is the best indicator of dehydration?
Correct Answer: Skin tenting when the client’s forearm is pinched.
Page 2 of 22
, HESI PHARMACOLOGY COMPREHENSIVE EXIT RN EXAM 2025-2026
6.
A client with heart failure is prescribed furosemide. Which laboratory value
should the nurse review prior to administering the medication?
Correct Answer: Serum potassium level.
7.
A client receiving warfarin therapy has an INR of 5.2. The client denies
bleeding. Which action should the nurse implement first?
Correct Answer: Hold the next dose of warfarin and notify the healthcare
provider.
8.
A client with type 1 diabetes receives regular insulin at 0800. At what time
should the nurse monitor the client most closely for signs of hypoglycemia?
Correct Answer: 1000.
9.
A client is prescribed digoxin for heart failure. The nurse assesses an apical
pulse of 54 beats per minute before administering the medication. What
should the nurse do?
Correct Answer: Hold the medication and notify the healthcare provider.
10.
A client receiving heparin therapy develops bleeding gums and hematuria.
Which medication should the nurse anticipate administering?
Correct Answer: Protamine sulfate.
11.
A client with hypertension is prescribed lisinopril. Which laboratory value
should the nurse monitor most closely while the client is taking this
medication?
Correct Answer: Serum potassium level.
12.
A client receiving insulin therapy reports symptoms of shakiness,
Page 3 of 22
HESI Pharmacology Comprehensive Exit RN
Exam 2025-2026 | Actual RN Exam With
Verified 170 Questions And Correct Answers
| Already Graded A+
HESI PHARMACOLOGY EXIT RN EXAM 2025–
2026
ACTUAL EXAM 170 QUESTIONS AND CORRECT ANSWERS | ALREADY GRADED
A+ | BRAND NEW!!
Overview
The HESI Pharmacology Exit RN Exam 2025–2026 Study Guide provides a
comprehensive and evidence-based review of essential medication knowledge
required for nursing practice. This exam preparation resource focuses on
pharmacologic principles, safe medication administration, and clinical
decision-making skills necessary for modern nursing care.
Covering critical topics such as drug classifications, therapeutic uses,
mechanisms of action, adverse reactions, dosage calculations, and nursing
interventions, this guide strengthens both theoretical knowledge and practical
application. Structured in a true HESI-style exam format, it supports nursing
students in developing the confidence and competence required to succeed on
the HESI Pharmacology Exit Exam and the Next Generation NCLEX (NGN).
Key Features
✓ 170 Verified HESI Pharmacology Exam Questions with Correct Answers
✓ Aligned with 2025–2026 HESI and NCLEX-RN Testing Standards
✓ A+ Graded and Expert-Reviewed for 100% Accuracy
✓ Realistic Exam Format for Authentic Practice
✓ Comprehensive Coverage of Pharmacology and Medication Safety
Page 1 of 22
,HESI PHARMACOLOGY COMPREHENSIVE EXIT RN EXAM 2025-2026
1.
A male client with stomach cancer returns to the unit following a total
gastrectomy. He has a nasogastric tube to suction and is receiving Lactated
Ringer's solution at 75 mL/hour IV. One hour after admission, the nurse notes
300 mL of blood in the suction canister, heart rate 155 beats/minute, and
blood pressure 78/48 mmHg. Which action should the nurse implement first?
Correct Answer: Increase the infusion rate of Lactated Ringer’s solution.
2.
An adult male who fell 20 feet from the roof of his home has multiple injuries
including a right pneumothorax. Chest tubes were inserted prior to transfer to
the ICU. The nurse observes bubbling in the suction control chamber and
fluctuation in the water seal chamber. Which intervention should the nurse
implement?
Correct Answer: Add sterile water to the suction control chamber.
3.
A client who received hemodialysis yesterday is experiencing blood pressure
of 200/100 mmHg, heart rate 110 beats/minute, respiratory rate 36
breaths/minute, and oxygen saturation of 89% on room air. Which action
should the nurse take first?
Correct Answer: Begin supplemental oxygen.
4.
A client with Addison’s crisis is admitted for treatment with adrenal
corticosteroids. Which findings require immediate nursing action? (Select all
that apply.)
Correct Answer: Irregular heart rate, pallor, tremors, and diaphoresis.
5.
An older client is admitted with dehydration and fluid volume deficit. Which
assessment finding is the best indicator of dehydration?
Correct Answer: Skin tenting when the client’s forearm is pinched.
Page 2 of 22
, HESI PHARMACOLOGY COMPREHENSIVE EXIT RN EXAM 2025-2026
6.
A client with heart failure is prescribed furosemide. Which laboratory value
should the nurse review prior to administering the medication?
Correct Answer: Serum potassium level.
7.
A client receiving warfarin therapy has an INR of 5.2. The client denies
bleeding. Which action should the nurse implement first?
Correct Answer: Hold the next dose of warfarin and notify the healthcare
provider.
8.
A client with type 1 diabetes receives regular insulin at 0800. At what time
should the nurse monitor the client most closely for signs of hypoglycemia?
Correct Answer: 1000.
9.
A client is prescribed digoxin for heart failure. The nurse assesses an apical
pulse of 54 beats per minute before administering the medication. What
should the nurse do?
Correct Answer: Hold the medication and notify the healthcare provider.
10.
A client receiving heparin therapy develops bleeding gums and hematuria.
Which medication should the nurse anticipate administering?
Correct Answer: Protamine sulfate.
11.
A client with hypertension is prescribed lisinopril. Which laboratory value
should the nurse monitor most closely while the client is taking this
medication?
Correct Answer: Serum potassium level.
12.
A client receiving insulin therapy reports symptoms of shakiness,
Page 3 of 22
