) | Questions & Answers
| Grade A | 100% Correct
Question:
Dermatitis herpetiformis (clusters of pruritic lesions) is associated with what
condition?
Answer:
Celiac disease.
Question:
Patient at 36 weeks gestation has itchiness in palms and soles. Next step?
Answer:
Check bile acid levels.
- Intrahepatic cholestasis of pregnancy (ICP): pruritus of palms/soles with or
without jaundice, elevated serum bile acid. MC in late 2nd and/or 3rd
trimester. Can cause significant risk to the fetus, including fetal death.
Treated aggressively with ursodeoxycholic acid and often early delivery.
,Question:
when to use omalizumab for asthma?
Answer:
Severe type 2 inflammatory asthma poorly controlled with optimal therapy
with long term medication, including high-dose corticosteroids and long
acting B agonist.
- According GINA guidelines, Management of severe asthma includes
determination of the asthma phenotype to assess for type 2 inflammation.
- Type 2 asthma includes allergic and eosinophilic asthma. (Elevated serum
eosinophils, elevated fractional exhaled nitric oxide).
- Non-type 2 asthma is driven by neutrophils and is associated with smoking
and obesity.
Question:
Persistent HTN is defined as ______.
Answer:
HTN despite 3 or more antiHTN rx, including a diuretics
,Question:
Best Evidence based treatment for Frailty syndrome?
A) Protein supplements
B) Vitamin D supplements
C) Hormonal treatment with anabolic steroids
D) Aerobic conditioning training
E) Progressive resistance training
Answer:
E) Progressive resistance training.
- Aerobic conditioning training may be helpful but NOT the strongest
evidence for efficacy.
- Routine use of protein supplements, vit D, or hormonal tx (anabolic
steroids) is NOT recommended.
, Question:
TSH 0.04, fT3 is 3.4, fT4 is 1.4 and RAIU scan shows multiple areas of
increased and suppressed uptake. Dx?
A) Exogenous thyroid hormone use
B) Graves
C) Painless thyroiditis
D) Excess iodine intake
E) Toxic multinodular goiter
Answer:
E) Toxic multinodular goiter.
- Low TSH, normal fT3/4 consistent with subclinical hyperthyroidism.
- RAIU shows multiple areas of INCREASED and SUPPRESSED uptake is
consistent with toxic multinodular goiter.
- Etiology determined by clx sxs, biochemical markers, and diagnostic studies
(RAIU) if indicated. If TSH persistently <0.1, the American Thyroid Assoc has
a strong recommendation with moderate-quality evidence for treating pt 65+
yoa, h/o cardiac risk factors, heart disease, osteoporosis, postmenopausal
women not on estrogen/ bisphosphonate or those with hyperthyroid sxs.
- There is no RAIU uptake with exogenous thyroid hormone ingestion,
painless thyroiditis, or excess iodine intake.
- Graves disease causes DIFFUSE RAIU!!!!!