to be diagnosed with MDD, you need one of two symptoms - Answers depressed mood; apathy/loss
of interest
to be diagnosed with MDD, you need 4/7 symptoms - Answers weight/appetite changes; sleep
disturbances; psychomotor; fatigue; worthlessness; executive dysfunction; suicidal ideation
pharmacological management of MDD - Answers SSRI, NDRI, SNRI, TCAs, MAOI
SSRI MOA - Answers selective serotonin reuptake inhibitor; increases serotonin in body
NDRI MOA - Answers norepinephrine dopamine reuptake inhibitor
SSRI use - Answers antidepressant, anxiety (first line)
NRDI use - Answers depression, smoking cessation
NRDI SE - Answers weight loss, reduced appetite, insomnia, elevated BP
SSRI SE - Answers GI upset, n/v, sexual dysfunction
SNRI MOA - Answers Serotonin norepinephrine reuptake inhibitor
SNRI uses - Answers depression; somatic pain; co-occuring pain disorder
SNRI SE - Answers GI upset, n/v, fatigue (take at night), weight loss, sexual dysfunction
Trazodone, Remeron - Answers depression; used when patient has sleep dysfunction (initiating sleep)
Tricyclic (TCAs) MOA - Answers increases all monoamines
TCA SE - Answers weight gain, dry mouth, sedation, cardiac effects
MAOI Example - Answers Nardil
MAOI consideration - Answers tyramine free diet
MAOI major issue - Answers hypertensive crisis
MAOI SE - Answers n/v, muscle twitching/hyperreflexia, headache, hypotension, ALT/AST elevation
(affects liver)
serotonin syndrome SE - Answers restless, agitation, hyper-reflexia, hyperthermia, tremor,
diaphoresis, diarrhea, headache, insomnia
Discontinuation syndrom SE - Answers lethargy, fatigue, myalgia (joint pain), anxiety, emotionally
lability
ECT - Answers induces seizures to treat depression
ECT SE - Answers headache, confusion, ST memory loss
grieving vs major depression - Answers grieving=2 mo; depression is longer
grief - Answers natural response to loss
mourning - Answers cultural/public display of grief
primary loss - Answers person (spouse, child, parent)
secondary - Answers role change that occurs due to losing the person
DSM for bipolar - Answers need both top plus 3 bottom OR 1/2 top and 4 of bottom
DSM bipolar top symptoms - Answers elevated/expansive mood; irritable mood
DSM bipolar bottom symtpoms - Answers inflated self-esteem/grandiosity; increased goal-directed
activity/agitation; risk taking; decreased need for sleep; distractible/concentration; more talkative
pressured speech; flight of ideas/racing thoughts
GABA bipolar - Answers lower level (relaxation)
glutamate bipolar - Answers excitatory (elevated in manie)
Bipolar I - Answers manic/depressive
Bipolar II - Answers mostly depressive, hypomania
cyclothymia - Answers moderate depressive/hypomanic
rapid cycling - Answers 4+ episodes in 12 months
biggest risk during manic episode - Answers safety
lithium treats what - Answers non-rapid cycler bipolar
lithium therapeutic range - Answers 0.6-1.2
effects of lithium toxicity - Answers projectile vomiting, tremors, sweating, diarrhea, ataxia, dizziness
who shouldn't take Lithium - Answers pregnant; ibuprofen use
Lamictal emergency - Answers Steven Johnson Syndrome
anxiety disorder vs anxiety - Answers symptoms impair functioning and occur for at least 6 months
first line treatment for anxiety - Answers antidepressants
biggest considerations for benzo - Answers dependence
non drug treatment for anxiety - Answers cognitive behavior therapy (redirect troubling thoughts)
treatment for phobia - Answers system desensitization, exposure therapy, biofeedback