NURS 660 EXAM 1 ANTIPSYCHOTIC
MEDICATIONS COMPLETE STUDY GUIDE
WITH VERIFIED ANSWERS 2026
⩥ Atypical Antipsychotics. Answer:What class of antipsychotic are these
Second Generation, Serotonin-Dopamine Receptor Antagonists
⩥ Dopamine D2 receptor. Answer:This receptor has the benefit of
reducing positive symptoms.
Possible side effects include: Parkinsonism, akathisia, tardive
dyskinesia, endocrine effects such as prolactin secretion, menstrual
changes and sexual dysfunction.
⩥ Serotonin 5-H2a receptor. Answer:This receptor has the benefit of
reducing EPS
Possible side effects: Sexual dysfunction
⩥ Serotonin 5HT2c receptor. Answer:The benefit of this receptor is
unknown
Side effect is weight gain
⩥ Histamine H-1 receptor. Answer:The benefit of this receptor is
sedation
,Side effects are sedation, increased appetite, weight gain and
hypotension
⩥ Muscarinic cholinergic receptors. Answer:The benefit of the receptor
is that it reduces EPS
Side effects are autonomic changes such as blurry vision, dry mouth,
constipation, urinary retention, tachycardia and memory dysfunction.
⩥ a1-adrenergic receptors. Answer:Benefit of receptor unknown
Side effects are orthostatic hypertension, dizziness and reflex
tachycardia.
⩥ a2-adrenergic receptors. Answer:Benefit of receptor unknown
Side effects are drug interactions
⩥ D2-Agonist actions?. Answer:What makes an antipsychotic
conventional?
⩥ D2 antagonist/First generation antipsychotics/Conventional
antipsychotics/Typical antipsychotics. Answer:These antipsychotics
share the primary pharmacological property of D2 antagonism, which is
responsible not only for their antipsychotic efficacy, but also for many of
their side effects.
, ⩥ Conventional Antipsychotic. Answer:These drugs have
pharmacological properties in addition to D2 antagonism, they block
muscarinic cholinergic receptors, histamine h-1 receptors and/or a1-
adrenergic receptors.
⩥ 60-80%. Answer:Antipsychotic properties happen when how much of
the D2 receptor is blocked?
⩥ 80%. Answer:The degree of binding in the mesolimbic pathway
needed for antipsychotic effects is?
⩥ extrapyramidal side effects. Answer:When greater that 80% of D2
receptors are occupied in the dorsal striatum what happens?
⩥ Pituitary gland. Answer:Which organ is associated with
hyperprolactinemia?
⩥ Aliphatic Phenothiazines (Chlorpromazine, Levomepromazine,
Promazine and Triflupromazine). Answer:These group of Phenothiazine
medications are low/medium potency agents, with high sedation,
medium anti-muscarinic effects, and medium extrapyramidal side
effects.
⩥ Piperidine (Mesoridazine, Pericyazine, Pipotiazine, and Thiordiazine).
Answer:This group of Phenothiazine medications are low-medium
MEDICATIONS COMPLETE STUDY GUIDE
WITH VERIFIED ANSWERS 2026
⩥ Atypical Antipsychotics. Answer:What class of antipsychotic are these
Second Generation, Serotonin-Dopamine Receptor Antagonists
⩥ Dopamine D2 receptor. Answer:This receptor has the benefit of
reducing positive symptoms.
Possible side effects include: Parkinsonism, akathisia, tardive
dyskinesia, endocrine effects such as prolactin secretion, menstrual
changes and sexual dysfunction.
⩥ Serotonin 5-H2a receptor. Answer:This receptor has the benefit of
reducing EPS
Possible side effects: Sexual dysfunction
⩥ Serotonin 5HT2c receptor. Answer:The benefit of this receptor is
unknown
Side effect is weight gain
⩥ Histamine H-1 receptor. Answer:The benefit of this receptor is
sedation
,Side effects are sedation, increased appetite, weight gain and
hypotension
⩥ Muscarinic cholinergic receptors. Answer:The benefit of the receptor
is that it reduces EPS
Side effects are autonomic changes such as blurry vision, dry mouth,
constipation, urinary retention, tachycardia and memory dysfunction.
⩥ a1-adrenergic receptors. Answer:Benefit of receptor unknown
Side effects are orthostatic hypertension, dizziness and reflex
tachycardia.
⩥ a2-adrenergic receptors. Answer:Benefit of receptor unknown
Side effects are drug interactions
⩥ D2-Agonist actions?. Answer:What makes an antipsychotic
conventional?
⩥ D2 antagonist/First generation antipsychotics/Conventional
antipsychotics/Typical antipsychotics. Answer:These antipsychotics
share the primary pharmacological property of D2 antagonism, which is
responsible not only for their antipsychotic efficacy, but also for many of
their side effects.
, ⩥ Conventional Antipsychotic. Answer:These drugs have
pharmacological properties in addition to D2 antagonism, they block
muscarinic cholinergic receptors, histamine h-1 receptors and/or a1-
adrenergic receptors.
⩥ 60-80%. Answer:Antipsychotic properties happen when how much of
the D2 receptor is blocked?
⩥ 80%. Answer:The degree of binding in the mesolimbic pathway
needed for antipsychotic effects is?
⩥ extrapyramidal side effects. Answer:When greater that 80% of D2
receptors are occupied in the dorsal striatum what happens?
⩥ Pituitary gland. Answer:Which organ is associated with
hyperprolactinemia?
⩥ Aliphatic Phenothiazines (Chlorpromazine, Levomepromazine,
Promazine and Triflupromazine). Answer:These group of Phenothiazine
medications are low/medium potency agents, with high sedation,
medium anti-muscarinic effects, and medium extrapyramidal side
effects.
⩥ Piperidine (Mesoridazine, Pericyazine, Pipotiazine, and Thiordiazine).
Answer:This group of Phenothiazine medications are low-medium
