MIC 205 EXAM 3 LECTURE QUESTIONS & ANSWERS
1. Sulfanilamide
A. were the first widely used antimicrobial drugs
B. are antimetabolic drugs.
C. indirectly inhibit the synthesis of nucleic acids.
D. Only A, and B are correct.
E. A, B, and C are correct. - Answers -E. A, B, and C are correct.
2. Sulfonamides are structural analogs of
A. MRSA
B. lipid A
C. PABA
D. MIC
E. THF - Answers -C. PABA
3. Semisynthetic drugs represent all of the following
improvements EXCEPT
A. they are broader spectrum in their action.
B. they are more stable in the stomach.
C. they are more readily absorbed in the intestines.
D. they are less susceptible to deactivation by bacterial enzymes.
E. All the above are true statements. - Answers -E. All the above are true statements.
4. Beta-lactamase production is an example of which of
the following types of resistance?
A. alternation of the target
B. removal of the drug via a pump
C overproduction of an enzyme in a key metabolic pathway
D. inactivation of the drug
E. change in the permeability of the drug - Answers -D. inactivation of the drug
5. All of the following are targets of drugs that inhibit
protein synthesis EXCEPT
A. interference with alanine-alanine bridges.
B. the enzymatic site of the 50S ribosomal subunit.
C. movement of the ribosome from one codon to the next.
D. the tRNA docking site.
E. the shape of the 30S ribosomal subunit. - Answers -A. interference with alanine-
alanine bridges.
1. Sulfanilamide
A. were the first widely used antimicrobial drugs
B. are antimetabolic drugs.
C. indirectly inhibit the synthesis of nucleic acids.
D. Only A, and B are correct.
E. A, B, and C are correct. - Answers -E. A, B, and C are correct.
2. Sulfonamides are structural analogs of
A. MRSA
B. lipid A
C. PABA
D. MIC
E. THF - Answers -C. PABA
3. Semisynthetic drugs represent all of the following
improvements EXCEPT
A. they are broader spectrum in their action.
B. they are more stable in the stomach.
C. they are more readily absorbed in the intestines.
D. they are less susceptible to deactivation by bacterial enzymes.
E. All the above are true statements. - Answers -E. All the above are true statements.
4. Beta-lactamase production is an example of which of
the following types of resistance?
A. alternation of the target
B. removal of the drug via a pump
C overproduction of an enzyme in a key metabolic pathway
D. inactivation of the drug
E. change in the permeability of the drug - Answers -D. inactivation of the drug
5. All of the following are targets of drugs that inhibit
protein synthesis EXCEPT
A. interference with alanine-alanine bridges.
B. the enzymatic site of the 50S ribosomal subunit.
C. movement of the ribosome from one codon to the next.
D. the tRNA docking site.
E. the shape of the 30S ribosomal subunit. - Answers -A. interference with alanine-
alanine bridges.
