MMSC490 UPDATED EVALUATION TEST QUESTIONS AND
SOLUTIONS GUARANTEE A+
✔✔Simple-sequence repeats
a. are present in tandem arrays of thousands of copies.
b. sediment as unique bands in equilibrium density-gradient centrifugation.
c. re-associate more rapidly than non-repeated sequences.
d. All of the above - ✔✔d. all of the above
✔✔Kinetochores are the
a. sites of spindle fiber attachment to chromosomes.
b. same as centromeres.
c. regions where two chromosomes remain attached during mitosis.
d. structures at the base of cilia and flagella. - ✔✔a. sites of spindle fiber attachment to
chromosomes.
✔✔Synthesis of different proteins from the same gene is due to
a. intron shuffling
b. exon shuffling
c. exon splicing
d. alternative splicing - ✔✔d. alternative splicing
✔✔Which of the following statements about exons is false?
a. exons are separated by introns
b. an exon may contain a 5' untranslated region
c. an exon may contain sequences for small nucleolar RNAs
d. an exon may contain a 3' untranslated region - ✔✔c. an exon may contain sequences
for small nucleolar RNAs
✔✔Nuclease digestion of chromatin occurs at sites separated by approximately 200
base pairs because
a. an AT-rich region occurs every 200 base pairs
b. a restriction nuclease site occurs every 200 base pairs
c. nucleosomes are spaced 200 base pairs apart
d. two turns of the DNA around the nucleosome consist of 200 base pairs - ✔✔c.
nucleosomes are spaced 200 base pairs apart
✔✔A gene family is a
a. family of individuals in which each has an identical sequence of the same gene
b. set of related but slightly different genes present in one individual
c. family of individuals with the same gene
d. set of slightly different genes present as one copy each in a set of individuals - ✔✔b.
set of related but slightly different genes present in one individual
,✔✔What is the term used to describe functional protein encoding regions found
completely within an intron?
a. polymorphism
b. alternative splicing
c. nested gene
d. pseudogene - ✔✔c. nested gene
✔✔The transfer of information from parent to progeny that is not based on DNA
sequence is known
a. non-Mendelian genetics
b. sex-linked inheritance
c. epigenetic inheritance
d. Mendelian genetics - ✔✔c. epigenetic inheritance
✔✔The extended length of all the DNA in one human cell is about two
a. inches
b. centimeters
c. meters
d. millimeters - ✔✔c. meters
✔✔The genomes of salamanders contain ten times more DNA than the genomes of
humans because salamanders
a. are more complex than humans
b. need more DNA so they can regenerate new limbs
c. have ten times more genes than humans have
d. have more noncoding DNA than humans have - ✔✔d. have more noncoding DNA
than humans have
✔✔A chromatosome is a complex of eight core
a. histones, two histone H1 molecules, and 166 base pairs of DNA
b. histones, one histone H1 molecule, and 166 base pairs of DNA
c. histone proteins
d. histone proteins and 146 base pairs of DNA - ✔✔b. histones, one histone H1
molecule, and 166 base pairs of DNA
✔✔Most of the euchromatin in interphase nuclei is in the form of .............. chromatin
fibers.
a. 2-nm
b. 30-nm
c. 300-nm
d. 10-nm - ✔✔b. 30-nm
✔✔Histone genes have
a. no introns
, b. larger exons than introns
c. larger introns than exons
d. a single long intron - ✔✔a. no introns
✔✔Retrotransposons and retroviruses share similar mechanisms by encoding which of
the following enzymes?
a. DNA polymerase and integrase
b. Reverse transcriptase and RNA polymerase
c. RNA polymerase and integrase
d. Reverse transcriptase and integrase - ✔✔d. Reverse transcriptase and integrase
✔✔Introns can encode
a. all of the above
b. microRNAs
c. sequences that control RNA processing
d. small nuclear RNAs - ✔✔a. all of the above
✔✔Results of cesium chloride density gradient centrifugation on genomic DNA often
reveal relatively small peaks of DNA that separate from the main genomic DNA peak
and consist of 1,000s of short repetitive sequences referred to as
a. long interspersed elements
b. satellite DNA
c. short interspersed elements
d. transposable elements - ✔✔b. satellite DNA
✔✔Extensive digestion of chromatin with micrococcal nuclease was found to yield
particles called nucleosome core particles that appear as beads when viewed by
electron microscopy. Which of the following is not found in the nucleosome core
particle?
a. Two molecules of H4 protein
b. Two molecules of of H2A protein
c. Two molecules of H3 protein
d. One molecule of H1 protein - ✔✔d. One molecule of H1 protein
✔✔Pseudogenes are
a. nonfunctional gene copies
b. inactive genes
c. genes containing variant sequences
d. genes that code for an RNA but do not code for a protein - ✔✔a. nonfunctional gene
copies
✔✔The human genome contains only 20,000 to 25,000 actual gene sequences, yet the
human genome can produce up to 100,000 gene products. Which of the following
processes accounts for this difference?
a. alternative splicing
SOLUTIONS GUARANTEE A+
✔✔Simple-sequence repeats
a. are present in tandem arrays of thousands of copies.
b. sediment as unique bands in equilibrium density-gradient centrifugation.
c. re-associate more rapidly than non-repeated sequences.
d. All of the above - ✔✔d. all of the above
✔✔Kinetochores are the
a. sites of spindle fiber attachment to chromosomes.
b. same as centromeres.
c. regions where two chromosomes remain attached during mitosis.
d. structures at the base of cilia and flagella. - ✔✔a. sites of spindle fiber attachment to
chromosomes.
✔✔Synthesis of different proteins from the same gene is due to
a. intron shuffling
b. exon shuffling
c. exon splicing
d. alternative splicing - ✔✔d. alternative splicing
✔✔Which of the following statements about exons is false?
a. exons are separated by introns
b. an exon may contain a 5' untranslated region
c. an exon may contain sequences for small nucleolar RNAs
d. an exon may contain a 3' untranslated region - ✔✔c. an exon may contain sequences
for small nucleolar RNAs
✔✔Nuclease digestion of chromatin occurs at sites separated by approximately 200
base pairs because
a. an AT-rich region occurs every 200 base pairs
b. a restriction nuclease site occurs every 200 base pairs
c. nucleosomes are spaced 200 base pairs apart
d. two turns of the DNA around the nucleosome consist of 200 base pairs - ✔✔c.
nucleosomes are spaced 200 base pairs apart
✔✔A gene family is a
a. family of individuals in which each has an identical sequence of the same gene
b. set of related but slightly different genes present in one individual
c. family of individuals with the same gene
d. set of slightly different genes present as one copy each in a set of individuals - ✔✔b.
set of related but slightly different genes present in one individual
,✔✔What is the term used to describe functional protein encoding regions found
completely within an intron?
a. polymorphism
b. alternative splicing
c. nested gene
d. pseudogene - ✔✔c. nested gene
✔✔The transfer of information from parent to progeny that is not based on DNA
sequence is known
a. non-Mendelian genetics
b. sex-linked inheritance
c. epigenetic inheritance
d. Mendelian genetics - ✔✔c. epigenetic inheritance
✔✔The extended length of all the DNA in one human cell is about two
a. inches
b. centimeters
c. meters
d. millimeters - ✔✔c. meters
✔✔The genomes of salamanders contain ten times more DNA than the genomes of
humans because salamanders
a. are more complex than humans
b. need more DNA so they can regenerate new limbs
c. have ten times more genes than humans have
d. have more noncoding DNA than humans have - ✔✔d. have more noncoding DNA
than humans have
✔✔A chromatosome is a complex of eight core
a. histones, two histone H1 molecules, and 166 base pairs of DNA
b. histones, one histone H1 molecule, and 166 base pairs of DNA
c. histone proteins
d. histone proteins and 146 base pairs of DNA - ✔✔b. histones, one histone H1
molecule, and 166 base pairs of DNA
✔✔Most of the euchromatin in interphase nuclei is in the form of .............. chromatin
fibers.
a. 2-nm
b. 30-nm
c. 300-nm
d. 10-nm - ✔✔b. 30-nm
✔✔Histone genes have
a. no introns
, b. larger exons than introns
c. larger introns than exons
d. a single long intron - ✔✔a. no introns
✔✔Retrotransposons and retroviruses share similar mechanisms by encoding which of
the following enzymes?
a. DNA polymerase and integrase
b. Reverse transcriptase and RNA polymerase
c. RNA polymerase and integrase
d. Reverse transcriptase and integrase - ✔✔d. Reverse transcriptase and integrase
✔✔Introns can encode
a. all of the above
b. microRNAs
c. sequences that control RNA processing
d. small nuclear RNAs - ✔✔a. all of the above
✔✔Results of cesium chloride density gradient centrifugation on genomic DNA often
reveal relatively small peaks of DNA that separate from the main genomic DNA peak
and consist of 1,000s of short repetitive sequences referred to as
a. long interspersed elements
b. satellite DNA
c. short interspersed elements
d. transposable elements - ✔✔b. satellite DNA
✔✔Extensive digestion of chromatin with micrococcal nuclease was found to yield
particles called nucleosome core particles that appear as beads when viewed by
electron microscopy. Which of the following is not found in the nucleosome core
particle?
a. Two molecules of H4 protein
b. Two molecules of of H2A protein
c. Two molecules of H3 protein
d. One molecule of H1 protein - ✔✔d. One molecule of H1 protein
✔✔Pseudogenes are
a. nonfunctional gene copies
b. inactive genes
c. genes containing variant sequences
d. genes that code for an RNA but do not code for a protein - ✔✔a. nonfunctional gene
copies
✔✔The human genome contains only 20,000 to 25,000 actual gene sequences, yet the
human genome can produce up to 100,000 gene products. Which of the following
processes accounts for this difference?
a. alternative splicing