Test bank for Tietz Fundamentals of Clinical Chemistry
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8th Edition by Nader Rifai, PhD
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Chapters 1 - 49 we we we we
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
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Table of contents:
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I. Principles Of Laboratory Medicine
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Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
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Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
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Chapter 3. Clinical Evaluation of Methods
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Chapter 4. Evidence-Based Laboratory Medicine
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Chapter 5. Establishment and Use of Reference Values
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Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
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Chapter 7. Quality Management
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II. Analytical Techniques And Instrumentation
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Chapter 8. Principles of Basic Techniques and Laboratory Safety
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Chapter 9. Optical Techniques
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Chapter 10. Electrochemistry and Chemical Sensors
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Chapter 11. Electrophoresis
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Chapter 12. Chromatography
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Chapter 13. Mass Spectrometry
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Chapter 14. Enzyme and Rate Analyses
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Chapter 15. Immunochemical Techniques
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Chapter 16 Automation we we
Chapter 17. Point-of-Care Instrumentation
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III. Analytes
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Chapter 18. Amino Acids, Peptides, and Proteins
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Chapter 19. Serum Enzymes
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Chapter 20. Tumor Markers and Cancer Genes
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Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
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Chapter 22. Carbohydrates
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Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
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Chapter 24. Electrolytes and Blood Gases
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Chapter 25. Hormones we we
Chapter 26. Catecholamines and Serotonin
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Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
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Chapter 28. Hemoglobin, Iron, and Bilirubin
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Chapter 29. Porphyrins and Porphyrias
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Chapter 30. Therapeutic Drugs and Their Management
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Chapter 31. Clinical Toxicology
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Chapter 32. Toxic Metals
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IV. Pathophysiology
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Chapter 33. Diabetes we we
,Chapter 34. Cardiovascular Disease
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Chapter 35. Kidney Disease
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Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
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Chapter 37. Liver Disease
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Chapter 38. Gastrointestinal and Pancreatic Diseases
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Chapter 39. Disorders of Bone and Mineral Metabolism
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Chapter 40. Disorders of the Pituitary Gland
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Chapter 41. Disorders of the Adrenal Cortex
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Chapter 42. Thyroid Disorders
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Chapter 43. Reproduction-Related Disorders
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Chapter 44. Pregnancy and Prenatal Testing
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Chapter 45. Newborn Screening and Inborn Errors of Metabolism
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Chapter 46. Pharmacogenetics
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V. Molecular Diagnostics
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Chapter 47. Principles of Molecular Biology
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Chapter 48. Nucleic Acid Techniques and Applications
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Chapter 49. Genomes and Nucleic Acid Alterations
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, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
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TestBank
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MULTIPLE CHOICE we
1. An individual working in a clinical chemistry laboratory is married to a sales
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representative who works for a company that sells chemistry laboratory supplies. When
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the laboratory manager requests a list of needed supplies, cost of supplies, and vendors,
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this individual onlyrecommends the spouse’s company as the vendor. This is considered
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to be a(n):
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a. accounting issue. we
b. possible conflict of interest. we we we
c. maintenance of confidentiality issue. we we we
d. problem with resource allocation. we we we
ANS: B w e
Concern has been raised over the interrelationships between practitioners in the medical
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fieldand commercial suppliers of drugs, devices, equipment, etc., to the medical
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profession.
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Similarly, relationships have been scrutinized between clinical laboratorians and
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manufacturers and providers of diagnostic equipment and supplies. These concerns led the
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National Institutes of Health (NIH) in 1995 to require official institutional review of
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financial disclosure by researchers and management of situations in which disclosure
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indicates potentialconflicts of interest.
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DIF: 1 REF: we we we Page 4-5 we OBJ: 6 | 7 w e we we
2. A patient visits her physician stating that her prescribed painkiller is not working to
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reduce the pain following her recent surgery. A friend of the patient claims that the
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same painkiller“worked wonders” to reduce her pain after the same surgery. The
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physician states that the difference in the effect of the drug might be caused by
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which is studied in pharmacogenetics.
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a. epidemiology
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c. a conflict of interest
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d. a genetic variation in drug-metabolizing enzymes
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ANS: D w e
Pharmacogenetics is the study of the genetic variation of drug metabolism we we we we we we we we we we
betweenindividuals.
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DIF: 1 REF: we we w e Page 3 we OBJ: 1 w e
3. John works in a molecular diagnostics laboratory and receives a blood sample that has
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the name of a close friend printed on the bar-coded label. The genetic test that is
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ordered on thefriend’s sample would provide diagnostic information about a disorder
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that has a poor prognosis, and the test is usually performed by John. He asks a fellow
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employee to analyzethe sample for him and not divulge the results. This ethical issue
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concerns:
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a. confidentiality of patient genetic and medical information. we we we we we we
b. a conflict of interest.
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c. resource allocation. we
d. diagnostic accuracy. we
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we and Molecular Diagnostics,
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8th Edition by Nader Rifai, PhD
we we we we we we
Chapters 1 - 49 we we we we
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
we we we we we we we we
we
we we
Table of contents:
we we
I. Principles Of Laboratory Medicine
we we we we
Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
we we we we we we we we
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
we we we we we we we we we we we
Chapter 3. Clinical Evaluation of Methods
we we we we we
Chapter 4. Evidence-Based Laboratory Medicine
we we we we
Chapter 5. Establishment and Use of Reference Values
we we we we we we we
Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
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Chapter 7. Quality Management
we we we
II. Analytical Techniques And Instrumentation
we we we we
Chapter 8. Principles of Basic Techniques and Laboratory Safety
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Chapter 9. Optical Techniques
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Chapter 10. Electrochemistry and Chemical Sensors
we we we we we
Chapter 11. Electrophoresis
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Chapter 12. Chromatography
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Chapter 13. Mass Spectrometry
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Chapter 14. Enzyme and Rate Analyses
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Chapter 15. Immunochemical Techniques
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Chapter 16 Automation we we
Chapter 17. Point-of-Care Instrumentation
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III. Analytes
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Chapter 18. Amino Acids, Peptides, and Proteins
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Chapter 19. Serum Enzymes
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Chapter 20. Tumor Markers and Cancer Genes
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Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
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Chapter 22. Carbohydrates
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Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
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Chapter 24. Electrolytes and Blood Gases
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Chapter 25. Hormones we we
Chapter 26. Catecholamines and Serotonin
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Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
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Chapter 28. Hemoglobin, Iron, and Bilirubin
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Chapter 29. Porphyrins and Porphyrias
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Chapter 30. Therapeutic Drugs and Their Management
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Chapter 31. Clinical Toxicology
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Chapter 32. Toxic Metals
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IV. Pathophysiology
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Chapter 33. Diabetes we we
,Chapter 34. Cardiovascular Disease
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Chapter 35. Kidney Disease
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Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
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Chapter 37. Liver Disease
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Chapter 38. Gastrointestinal and Pancreatic Diseases
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Chapter 39. Disorders of Bone and Mineral Metabolism
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Chapter 40. Disorders of the Pituitary Gland
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Chapter 41. Disorders of the Adrenal Cortex
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Chapter 42. Thyroid Disorders
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Chapter 43. Reproduction-Related Disorders
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Chapter 44. Pregnancy and Prenatal Testing
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Chapter 45. Newborn Screening and Inborn Errors of Metabolism
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Chapter 46. Pharmacogenetics
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V. Molecular Diagnostics
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Chapter 47. Principles of Molecular Biology
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Chapter 48. Nucleic Acid Techniques and Applications
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Chapter 49. Genomes and Nucleic Acid Alterations
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, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
we we we we we we we we
TestBank
we ew
MULTIPLE CHOICE we
1. An individual working in a clinical chemistry laboratory is married to a sales
we we we we we we we we we we we we
representative who works for a company that sells chemistry laboratory supplies. When
we we we we we we we we we we we we
the laboratory manager requests a list of needed supplies, cost of supplies, and vendors,
we we we we we we we we we we we we we we
this individual onlyrecommends the spouse’s company as the vendor. This is considered
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to be a(n):
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a. accounting issue. we
b. possible conflict of interest. we we we
c. maintenance of confidentiality issue. we we we
d. problem with resource allocation. we we we
ANS: B w e
Concern has been raised over the interrelationships between practitioners in the medical
we we we we we we we we we we we
fieldand commercial suppliers of drugs, devices, equipment, etc., to the medical
we ew we we we we we we we we we we
profession.
we
Similarly, relationships have been scrutinized between clinical laboratorians and
we we we we we we we we
manufacturers and providers of diagnostic equipment and supplies. These concerns led the
we we we we we we we we we we we we
National Institutes of Health (NIH) in 1995 to require official institutional review of
we we we we we we we we we we we we we
financial disclosure by researchers and management of situations in which disclosure
we we we we we we we we we we we
indicates potentialconflicts of interest.
we we ew we we
DIF: 1 REF: we we we Page 4-5 we OBJ: 6 | 7 w e we we
2. A patient visits her physician stating that her prescribed painkiller is not working to
we we we we we we we we we we we we we
reduce the pain following her recent surgery. A friend of the patient claims that the
we we we we we we we we we we we we we we we
same painkiller“worked wonders” to reduce her pain after the same surgery. The
we we ew we we we we we we we we we we
physician states that the difference in the effect of the drug might be caused by
we we , we we we we we we we we we we we we we
which is studied in pharmacogenetics.
we we we we we
a. epidemiology
b. an inherited disease we we
c. a conflict of interest
we we we
d. a genetic variation in drug-metabolizing enzymes
we we we we we
ANS: D w e
Pharmacogenetics is the study of the genetic variation of drug metabolism we we we we we we we we we we
betweenindividuals.
we ew
DIF: 1 REF: we we w e Page 3 we OBJ: 1 w e
3. John works in a molecular diagnostics laboratory and receives a blood sample that has
we we we we we we we we we we we we we
the name of a close friend printed on the bar-coded label. The genetic test that is
we we we we we we we we we we we we we we we we
ordered on thefriend’s sample would provide diagnostic information about a disorder
we we we ew we we we we we we we we
that has a poor prognosis, and the test is usually performed by John. He asks a fellow
we we we we we we we we we we we we we we we we we
employee to analyzethe sample for him and not divulge the results. This ethical issue
we we we ew we we we we we we we we we we we
concerns:
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a. confidentiality of patient genetic and medical information. we we we we we we
b. a conflict of interest.
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c. resource allocation. we
d. diagnostic accuracy. we