2025 AQA GCSE COMBINED SCIENCE: TRILOGY 8464/B/1H
Higher Tier Biology Paper 1H
Question Paper with Marking Scheme Attached
Please write clearly in block capitals.
Centre number Candidate number
Surname
Forename(s)
Candidate signature
I declare this is my own work.
GCSE
COMBINED SCIENCE: TRILOGY
Higher Tier
H
Biology Paper 1H
Tuesday 13 May 2025 Afternoon Time allowed: 1 hour 15 minutes
Materials For Examiner’s Use
For this paper you must have:
• a ruler Question Mark
• a scientific calculator. 1
2
Instructions
3
• Use black ink or black ball-point pen.
• Pencil should only be used for drawing. 4
• Fill in the boxes at the top of this page. 5
• Answer all questions in the spaces provided.
6
• If you need extra space for your answer(s), use the lined pages at the end of
this book. Write the question number against your answer(s). TOTAL
• Do all rough work in this book. Cross through any work you do not want to be
marked.
• In all calculations, show clearly how you work out your answer.
Information
• The maximum mark for this paper is 70.
• The marks for questions are shown in brackets.
• You are expected to use a calculator where appropriate.
• You are reminded of the need for good English and clear presentation in your answers.
, 2
Do not write
outside the
0 1 The heart is an organ that pumps blood around the body. box
Figure 1 is a model of the heart and shows the direction of blood flow.
Figure 1
0 1 . 1 Draw one line from each blood vessel shown in Figure 1 to the name of the
blood vessel.
[2 marks]
IB/M/Jun25/8464/B/1H
, 3
Do not write
outside the
0 1 . 2 Heart rate is controlled by a group of cells. box
The group of cells acts as a pacemaker.
Where would the pacemaker be located in Figure 1?
[1 mark]
Tick (✓) one box.
C D E F
0 1 . 3 Heart muscle cells contain many mitochondria.
Explain why heart muscle cells contain many mitochondria.
[3 marks]
Question 1 continues on the next page
Turn over ►
IB/M/Jun25/8464/B/1H
, 4
Do not write
outside the
A small number of people are born with a ‘hole in the heart’. box
Figure 2 shows the position of a hole in the heart.
Figure 2
0 1 . 4 The hole allows some blood from the right side of the heart to mix with blood in the left
side of the heart.
Suggest two symptoms of having a hole in the heart.
[2 marks]
1
2
IB/M/Jun25/8464/B/1H
Higher Tier Biology Paper 1H
Question Paper with Marking Scheme Attached
Please write clearly in block capitals.
Centre number Candidate number
Surname
Forename(s)
Candidate signature
I declare this is my own work.
GCSE
COMBINED SCIENCE: TRILOGY
Higher Tier
H
Biology Paper 1H
Tuesday 13 May 2025 Afternoon Time allowed: 1 hour 15 minutes
Materials For Examiner’s Use
For this paper you must have:
• a ruler Question Mark
• a scientific calculator. 1
2
Instructions
3
• Use black ink or black ball-point pen.
• Pencil should only be used for drawing. 4
• Fill in the boxes at the top of this page. 5
• Answer all questions in the spaces provided.
6
• If you need extra space for your answer(s), use the lined pages at the end of
this book. Write the question number against your answer(s). TOTAL
• Do all rough work in this book. Cross through any work you do not want to be
marked.
• In all calculations, show clearly how you work out your answer.
Information
• The maximum mark for this paper is 70.
• The marks for questions are shown in brackets.
• You are expected to use a calculator where appropriate.
• You are reminded of the need for good English and clear presentation in your answers.
, 2
Do not write
outside the
0 1 The heart is an organ that pumps blood around the body. box
Figure 1 is a model of the heart and shows the direction of blood flow.
Figure 1
0 1 . 1 Draw one line from each blood vessel shown in Figure 1 to the name of the
blood vessel.
[2 marks]
IB/M/Jun25/8464/B/1H
, 3
Do not write
outside the
0 1 . 2 Heart rate is controlled by a group of cells. box
The group of cells acts as a pacemaker.
Where would the pacemaker be located in Figure 1?
[1 mark]
Tick (✓) one box.
C D E F
0 1 . 3 Heart muscle cells contain many mitochondria.
Explain why heart muscle cells contain many mitochondria.
[3 marks]
Question 1 continues on the next page
Turn over ►
IB/M/Jun25/8464/B/1H
, 4
Do not write
outside the
A small number of people are born with a ‘hole in the heart’. box
Figure 2 shows the position of a hole in the heart.
Figure 2
0 1 . 4 The hole allows some blood from the right side of the heart to mix with blood in the left
side of the heart.
Suggest two symptoms of having a hole in the heart.
[2 marks]
1
2
IB/M/Jun25/8464/B/1H
