Mice Rats Hamster Guinea pig Rabbit
Strains - Dwarf mouse Zuckerrat / Dunkin-Hartley Dutch, New-Zealand
dw/dw (C3H/HeJ) Inheritable obesity White
-Obese mouse
ob/ob
-Nude mouse
No thymus
Harderian gland Harderian gland Hip glands Sebaceous glands On chin and around
Glands
in fossa perinealis anus
Postpartum oestrus Yes Yes Yes, but not fertile Yes Yes
Lee-Boot and Whitten Less clear Lee-Boot / / /
Effects
effect, Bruce effect and Whitten effect
Breeding systems Mono, trio, harem Mono, trio, harem Mono, harem (difficult) Mono, harem /
Anogenital distance Anogenital distance Anogenital distance Penis appears with Penis
Sexting
pressure
Copulation plug Yes Yes / / /
Conventional animal facility Semi-barrier A2-animal facility Specified pathogen-free (SPF) facility
- Multifunctional rooms = keeps unwanted MO out = keeps pathogens in = keeps MO out
- Maximum flexibility - Barrier units or Isolators - Everything in one - One corridor barrier or Double
- Large corridor - Ventilated cabinets or sterile zone, even corridor barrier with single or
Filtertop cages or washing and double rooms
Individually ventilated autoclaving units - Metabolic cages
cages (IVC)
- Sterile air, in and out
Nude mutation Scid mutation Beige mutation
Can’t produce T-cells Can’t produce B-cells Can’t produce NK-Cells
Strains - Dwarf mouse Zuckerrat / Dunkin-Hartley Dutch, New-Zealand
dw/dw (C3H/HeJ) Inheritable obesity White
-Obese mouse
ob/ob
-Nude mouse
No thymus
Harderian gland Harderian gland Hip glands Sebaceous glands On chin and around
Glands
in fossa perinealis anus
Postpartum oestrus Yes Yes Yes, but not fertile Yes Yes
Lee-Boot and Whitten Less clear Lee-Boot / / /
Effects
effect, Bruce effect and Whitten effect
Breeding systems Mono, trio, harem Mono, trio, harem Mono, harem (difficult) Mono, harem /
Anogenital distance Anogenital distance Anogenital distance Penis appears with Penis
Sexting
pressure
Copulation plug Yes Yes / / /
Conventional animal facility Semi-barrier A2-animal facility Specified pathogen-free (SPF) facility
- Multifunctional rooms = keeps unwanted MO out = keeps pathogens in = keeps MO out
- Maximum flexibility - Barrier units or Isolators - Everything in one - One corridor barrier or Double
- Large corridor - Ventilated cabinets or sterile zone, even corridor barrier with single or
Filtertop cages or washing and double rooms
Individually ventilated autoclaving units - Metabolic cages
cages (IVC)
- Sterile air, in and out
Nude mutation Scid mutation Beige mutation
Can’t produce T-cells Can’t produce B-cells Can’t produce NK-Cells
